Search Results - xinyuan+chong

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Novel Zinc Metallochaperone (ZMC) Complexes for Treatment of p53-Mutated Cancers
A) Novel mechanism of action: a short exposure to ZMCs increases zinc levels in tumors enough to restore normal structure/function to mutant p53 which leads to p53 mediated cancer cell death. B) Novel formulation: Synthesizing ZMCs as a zinc-loaded complex (Zn-1) improves survival in a pancreatic cancer mouse model compared to the ZMC compound alone....
Published: 12/4/2024   |   Inventor(s): Darren Carpizo, David Augeri, Spencer Kimball, Xin Yu
Keywords(s): Anti-cancer, Small molecules
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
ComprehENotes: Assessing patients' comprehension of their medical conditions and treatment
Many medical patients are now able to directly access their electronic health records (EHR). Providing such direct access has been shown to lead to improved healthcare outcomes through the patient’s enhanced understanding of their medical conditions and treatment. However, EHR contain medical jargon that challenge populations with lower health...
Published: 6/26/2023   |   Inventor(s): John Lalor, Hao Wu, Li Chen, Kathleen Mazor, Hong Yu
Keywords(s):  
Category(s): Healthcare, Research tools
A System For Visual Presentation Of Concepts From Ontology And Text Documents
PAGE TITLEOverviewPAGE SUMMARYA system lets a user click on a location of a brain model to explore neuroscience ontology terms related to the location. The user can further explore the related terms and related documents through a visualization interface and learn new concept or document relationships derived from the ontology and annotated document...
Published: 7/24/2024   |   Inventor(s): Yuan An, Xia Lin, Mi Zhang, Yue Shang
Keywords(s):  
Category(s): Computing, Software, Analytics & Information Technology, Computing, Software, Analytics & Information Technology > Computing: Algorithms, Computing, Software, Analytics & Information Technology > Computing: Contextual Analytics, Computing, Software, Analytics & Information Technology > Computing: Data Mining, Computing, Software, Analytics & Information Technology > Computing: Databases
Conductive Metalorganic Framework Chemical Sensors
Technology Description This technology is a gas sensing device made of a highly oriented metal-organic framework (MOF) material on an oxide substrate. The MOF is also made conductive by the addition of a redox active molecule. The conductive MOF is made without using a gold substrate, and the method of assembling the MOF layers incorporating the redox...
Published: 12/23/2021   |   Inventor(s): Chih-Hung Chang, Ki-Joong Kim, Alan Wang, Yujing Zhang, Xinyuan Chong
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Chemicals / Chemical Engineering, Sensors
Category(s): Chemical, Device, Engineering, Materials Science, Nanoscience & Microtechnologies, Physical Science
Chance-Constrained Optimization for Treatment of Prostate and Other Cancers in Intensity-Modulated Proton Therapy
The quality of IMPT treatment plans may be drastically diminished by uncertainties such as proton range and patient setup errors. If these uncertainties are not figured into treatment planning, the dose distribution that the patient receives may not be the same as the planned dose distribution. New treatment plans, which include optimized software/programming,...
Published: 12/18/2024   |   Inventor(s): Jianming Liang, Yu An, Wei Liu
Keywords(s):  
Category(s): Computing & Information Technology, Life Science (All LS Techs), Medical Imaging
Fiber Optic Infrared Absorption Gas Sensors with Metal-Organic Framework Materials
Technology Description The fiber-optic chemical sensing platform couples light guides with a metal-organic framework (MOF) and plasmonic nanomaterial sensing components to provide increased near-infared (NIR) detection sensitivity. The MOF thin films rapidly absorb and sense gases by leveraging a network of plasmonic nanocrystals that act at the NIR...
Published: 12/23/2021   |   Inventor(s): Alan Wang, Chih-Hung Chang, Paul Ohodnicki, Ki-Joong Kim, Xinyuan Chong
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), fiber optics, Sensors
Category(s): Engineering
Making Dihydroxyacetone (DHA) from Glycerol
IntroductionDihydroxyacetone (DHA) is used as an ingredient in sunless tanning products and in the food preparation industry. DHA’s skin coloring effect has also been examined to determine if it may benefit vitiligo patients (an uneven pigmentation of the skin); several DHA-containing products for this condition are now on the market. In recent...
Published: 2/17/2023   |   Inventor(s): Dennis Miller, Xi Hong, Carl Lira, Omar Mcgiveron
Keywords(s): DHA, Dihydroxyacetone, Glycerol Fermentation
Category(s): Chemicals