Search Results - wenlin+zhang

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Transgenic Mouse Model for Marfan Syndrome Research

Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...

Published: 12/23/2025 | Inventor(s): Li Li, Shichao Wu, Jiawei Zhao

Keywords(s):

Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic

Low-Cost High-Performance 3D LiDAR Imaging System

Description: This innovative 3D imaging system uses time-of-flight measurement of photons with a conventional global shutter CMOS camera to generate accurate distance data converted into brightness levels. It includes a laser source, camera, delay generator, master trigger, and electronic control unit (ECU) which together capture and average multiple...

Published: 12/16/2025 | Inventor(s): Wen Li, Suk Kyoung Lee, Blessed Oguh, Sulaiman Abubakar

Keywords(s):

Category(s): Technology Category > Automotive & Transportation, Technology Category > Physical Sciences, Technology Category > Image Analysis (Cameras & Software), Technology Category > Revolutionizing Mobility

Ultrafast Thin-Film Vapor Deposition Technique

Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...

Published: 11/18/2025 | Inventor(s): Feng Yan, Lin Li

Keywords(s):

Category(s): Semiconductors, Materials & Processes, Microelectronics, Physical Science, Semiconductor Devices, Manufacturing/Construction/Mechanical

Bioplatform to Identify and Characterize Pathogens and Therapies against Tuberculosis and Other Granulomatous Diseases.

Treatment for human tuberculosis (TB) and other granulomatous diseases would benefit from high- throughput screening (HTS)-compatible platform replicating physiological conditions in hallmark granuloma lesions. However, currently available screening platforms and 2-D and 3-D cell culture systems lack throughput and key features, and relevant microenvironments...

Published: 5/9/2025 | Inventor(s): Suraj Sable, James Posey, Wen Li, Allison Kline

Keywords(s):

Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

CHST6 Mini Gene - CHST6 Expression Construct With Native Promoter (UCLA Case No. 2023-301)

UCLA researchers from the Department of Human Genetics and Department of Ophthalmology have developed a mini gene encoding a protein which is mutated in macular corneal dystrophy, leading to a potential gene therapy for this disorder. BACKGROUND: Macular corneal dystrophy (MCD) is a rare genetic disease caused by mutations in the CHST6 gene, which...

Published: 7/17/2025 | Inventor(s): Wenlin Zhang, Anthony Aldave

Keywords(s): AAV, Adeno-associated viruses (AAV), Gene Editing Systems, Gene Therapy, genetics, keratinocytes, macular corneal dystrophy, mini gene, mutation, native promoter, Ophthalmology

Category(s): Therapeutics > Ophthalmology, Therapeutics > Gene Therapy And Editing

Heavy Metal Sensing

VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...

Published: 10/21/2025 | Inventor(s): Wen Li, Hasan Banna, James Siegenthaler, Mohammad Kafi Kangi, Tumi Olason

Keywords(s):

Category(s): Agriculture, Analytical Instruments, Environment, Test and Measurement

Electronic Fringe Scanning for the Improvement of Medical Imaging Technology

This technology includes an electronic method for fringe scanning in grating-based phase-contrast imaging, which enhances x-ray phase-contrast imaging. Traditional methods use high-density gratings and require fine grating fringes, finer than the detector's resolution, necessitating fringe scanning to obtain phase-contrast information. This process...

Published: 8/12/2024 | Inventor(s): Han Wen

Keywords(s):

Category(s): Application > Medical Devices, Collaboration Sought > Licensing, ResearchProducts > Research Equipment

Hybrid Computer Tomography Scanning System

The invention relates to a combination hybrid computer tomography (CT) system that is particularly suited for elucidating stages in pulmonary diseases, notably cystic fibrosis and lung cancer. Improved visualization of lung parenchyma and the margins of lung cysts (non-invasive “virtual biopsy”) may provide sufficient detail to distinguish the types...

Published: 8/13/2025 | Inventor(s): Han Wen

Keywords(s): AA3B6X, AA3CXX, CT, HYBRID, lung cancer, Lung Disease, Lung-Targeted, Pulmonary, PULMONARY FIBROSIS, WBXXXX, XFXXXX, X-RAY, YAXXXX

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Medical Devices, Application > Non-Medical Devices, Application > Software / Apps

A Novel X-ray Grating to Enhance Phase Contrast Imaging

The present invention relates to improving x-ray phase contrast imaging. The invention discloses a novel grating interferometer for phase contrast imaging with hard x-rays that overcomes limitations in the level of sensitivity by utilizing the advantages of far-field interferometers. The novel design and fabrication process can easily acquire absolute...

Published: 10/28/2024 | Inventor(s): Han Wen

Keywords(s): AA3XXX, Balanced, GRATING, INTERFEROMETER, Two-arm, VCXXXX, VDXXXX, WBXXXX, WIXXXX, XDXXXX, XFXXXX, X-RAY, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, Application > Software / Apps, Application > Medical Devices, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Oncology

A Novel Demodulation System in X-ray Imaging

In various x-ray imaging methods, including scattering correction and phase contrast imaging, intensity modulation in space is introduced into the projection images by the use of masks, gratings, or apertures. The present invention relates to a process to demodulate the modulation. The current demodulation processes are either to remove the modulation...

Published: 10/28/2024 | Inventor(s): Houxun Miao, Han Wen

Keywords(s): AA3XXX, Demodulation, IMAGING, INTENSITY, Modulation, VCXXXX, VDXXXX, VEXXXX, VPXXXX, WBXXXX, WIXXXX, XDXXXX, XFXXXX, X-RAY, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Ophthalmology, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Software / Apps, TherapeuticArea > Neurology, Application > Research Materials, Application > Diagnostics, Application > Medical Devices

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