Search Results - ulcerative+colitis

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Muramyl Dipeptide as a Therapeutic Agent for Inflammation
The nucleotide-binding oligomerization domain 2 (NOD2) protein plays a key role in innate immunity as a sensor of muramyl dipeptide (MDP), a breakdown product of bacterial peptidoglycan. Bacterial peptidoglycan promotes the innate immune response through the activation of Toll-like receptor 2 (TLR2), which ultimately provokes inflammation. Activation...
Published: 10/28/2024   |   Inventor(s): Warren Strober
Keywords(s): Autoimmune, AUTOIMMUNE DISEASE, Autoimmune disorder, Autoimmunity, BBXXXX, BCXXXX, BOWEL, Crohn disease; Inflammatory bowel disease 1, Crohn's disease, Dipeptide, IB3XXX, IBD, IBXXXX, IL-12, Inflammation, INFLAMMATORY, inflammatory bowel disease, Inflammatory bowel disease 1, inflammatory disease, INTERLEUKIN, INTERLEUKIN-12, IRF4, IXXXXX, MDP, Muramyl, NOD2, peptidoglycan, TLR, TLR2, Toll-like, Toll-like receptors, Ulcerative Colitis
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics
Prodrugs of Short-Chain Fatty Acids for Treatment of Intestinal Disorders and Colon Cancer
Current State of the Art: Colon cancer, IBS, Crohn’s disease and colitis present as some of the most difficult diseases to treat with the medications available currently. Treatment can be as drastic as surgery, chemotherapy, medications, such as cortisone, which can have sometimes serious and debilitating side effects. Colon cancer is treated with...
Published: 4/28/2020   |   Inventor(s): Vadivel Ganapathy, Puttur Prasad, Robert Martindale
Keywords(s): Colon Cancer, Inflammatory Bowel Disease, Ulcerative Colitis
Category(s): Therapeutics