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Search Results - therapeutics+%3e+psychiatry+and+mental+health
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Mental Health Functional Movement Scale (MH-FMS) (Case No. 2025-021)
Summary: UCLA researchers in the Department of Psychiatry and Behavioral Sciences have created a novel assessment platform that objectively measures how the brain, body, and autonomic nervous system respond to stress and regulate emotion during real-time movement. By integrating a shear-stress–based neurovascular framework with a polyvagal-informed...
Published: 12/17/2025
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Inventor(s):
Naser Ahmadi
,
Mike Ramirez
,
Julien Pineau
Keywords(s):
blood flow management
,
Cardiovascular
,
cellular
,
clinical care methodology
,
clinical decision support
,
Clinical decision support system
,
clinical mental health
,
Clinical tool
,
exercise physiology
,
Hemodynamics
,
Mental health
,
neurobehavioral impairment
,
Neurocognitive
,
Neurocognitive Scientific Method
,
neurodevelopment
,
neurological disorders
,
Neuropsychological Test
,
neuroscience
,
Neurostimulation
,
Psychiatry / Mental Health
Category(s):
Diagnostic Markers
,
Life Science Research Tools
,
Medical Devices
,
Medical Devices > Hospital Systems
,
Therapeutics
,
Therapeutics > Psychiatry And Mental Health
Compounds for Reversing the Adverse Effects of Early Life Adversity During Childhood (UCLA Case No. 2021-078)
Compositions and methods for diagnosing patients with a history of early-life adversity (ELA), and for preventing, treating, or reducing psychological distress in patients with a history of ELA. Contact UCLA Technology Development Group for more information.
Published: 11/25/2025
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Inventor(s):
Arpana Church
Keywords(s):
Category(s):
Therapeutics > Psychiatry And Mental Health
Therapeutic Targets from Subproteomes of Astrocytes and Neurons (UCLA Case No. 2024-162)
UCLA researchers in the Department of Physiology have identified specific endogenous receptors that activate an astrocyte signaling pathway, which is beneficial for restoring astrocyte morphology and ameliorating phenotypes associated with obsessive-compulsive disorder and other brain disorders. BACKGROUND: Obsessive-compulsive disorder (OCD) is a...
Published: 10/30/2025
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Inventor(s):
Baljit Khakh
Keywords(s):
Category(s):
Therapeutics > CNS and Neurology
,
Therapeutics > Psychiatry And Mental Health
A Microbial Metabolite That Promotes Stress/Anxiety (UCLA Case No. 2026-007)
Contact UCLA Technology Development Group to learn more.
Published: 9/19/2025
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Inventor(s):
Elaine Hsiao
Keywords(s):
Category(s):
Therapeutics > Psychiatry And Mental Health
,
Therapeutics > Metabolism And Endocrinology
Non-invasive Pain Measurement of Infants and Toddlers Using Acoustic Features of Cries (Copyright; Case No. 2018-327)
Summary: Researchers in the UCLA Semel Institute for Neuroscience and Human Behavior have developed a novel, non-invasive pain measurement tool for neonates. Background: Pain management in neonatal care remains a critical unmet need. Approximately 90% of premature infants undergo painful procedures, yet pain is only reported in 45% of cases. Current...
Published: 4/21/2025
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Inventor(s):
Ariana Anderson
Keywords(s):
acoustics
,
artificial intelligence/machine learning models
,
Digital Signal Processing
,
Machine Learning Pain Management
,
Monitoring (Medicine)
,
non-invasive monitoring
,
Pain Treatment
,
pediatrics
Category(s):
Diagnostic Markers > Pediatrics
,
Medical Devices > Monitoring And Recording Systems
,
Platforms > Diagnostic Platform Technologies
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Software & Algorithms > AI Algorithms
,
Software & Algorithms > Data Analytics
,
Software & Algorithms > Digital Health
,
Therapeutics > Critical Care
,
Therapeutics > Psychiatry And Mental Health
Microbial Metabolites for Promoting Brain Health (UCLA Case No. 2024-196)
UCLA researchers in the Department of Integrative Biology and Physiology have developed a maternal supplementation with microbiome-dependent metabolites to promote growth and neurobehavioral health in children impacted by maternal protein undernutrition. BACKGROUND: Protein undernutrition poses a significant risk of childhood stunting, accompanying...
Published: 7/17/2025
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Inventor(s):
Elaine Hsiao
Keywords(s):
Brain
,
brain health
,
growth defects
,
malnutrition
,
maternal supplementation
,
microbial metabolites
,
microbiome
,
neurobehavioral impairment
,
neurodevelopment
,
nutrition
,
protein undernutrition
,
stunting
Category(s):
Therapeutics > CNS and Neurology
,
Therapeutics > Gastroenterology
,
Therapeutics > Psychiatry And Mental Health
Creation of a Specified Probiotic Blend to Help with Weight Loss and Associated Metabolic Disease (UCLA Case No. 2023-258)
UCLA researchers in the Department of Medicine, Vatche and Tamar Manoukin Division of Digestive Diseases have developed a novel probiotic blend composed of two gut bacteria strains. This blend has the potential to be a safe supplement for treating food addiction, obesity, cognition, and other associated metabolic diseases in humans. BACKGROUND: Obesity...
Published: 7/17/2025
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Inventor(s):
Arpana Church
Keywords(s):
bacterial strain
,
brain reward system
,
brain-gut microbiome
,
food addiction
,
food metabolism
,
gut-brain axis
,
Mental health
,
Metabolic Diseases
,
Nutraceuticals / Probiotics
,
nutritional supplement
,
obesity
Category(s):
Therapeutics > Metabolism And Endocrinology
,
Therapeutics > Gastroenterology
,
Therapeutics > Psychiatry And Mental Health
Compounds for Improved Psychological and Resilience Measures Associated with Physical Activity (UCLA Case No. 2022-272)
UCLA researchers from the Department of Medicine have identified microbiome and metabolic markers associated with high physical activity in an obese population, leading to possible therapies that may provide the positive effects of physical activity. BACKGROUND: It is known that physical activity has a multitude of beneficial effects on health. On...
Published: 7/17/2025
|
Inventor(s):
Arpana Church
Keywords(s):
Bacteria
,
Exercise
,
Gastroenterology & Digestive Disease
,
gut-brain axis
,
Human Gastrointestinal Tract
,
metabolomics
,
microbiome
,
MRI
,
Nutraceuticals / Probiotics
,
obesity
,
physical activity
,
prebiotics
,
Psychology
Category(s):
Therapeutics > Gastroenterology
,
Therapeutics > Psychiatry And Mental Health
,
Therapeutics > Metabolism And Endocrinology
2019-265: Engineered Mammalian Animal and Cell Models to Enable the Identification of Molecules That Target Microglia and Myeloid Cell Function
SUMMARY UCLA researchers in the Department of Psychiatry have developed novel methods to use human genomic DNA context to drive the expression of microglial-expressing Alzheimer’s disease genes in mammalian cells or mammalian animal models. BACKGROUND Microglia are resident innate immune cells in the brain derived from myeloid precursors....
Published: 7/17/2025
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Inventor(s):
X. William Yang
Keywords(s):
Category(s):
Life Science Research Tools > Research Methods
,
Therapeutics > Psychiatry And Mental Health
2021-241: Enhancers of Brain Gamma Oscillations for Treatment of Neurological Disorders
SUMMARY: UCLA researchers in the Department of Neurology have developed a novel small molecule to improve native gamma oscillations as a treatment for cognitive decline in various neurological disorders. BACKGROUND: Neural circuits are facilitated by brain oscillations or rhythmic electric activity at distinct frequencies. These frequency variations...
Published: 7/17/2025
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Inventor(s):
Varghese John
,
Istvan Mody
,
Jesus Campagna
,
Barbara Jagodzinska
,
Xiaofei Wei
Keywords(s):
Category(s):
Therapeutics > CNS and Neurology
,
Therapeutics > Psychiatry And Mental Health
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