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Device For Rapid, Tunable, And Scalable Generation Of Lipid Nanoparticle Formulations
Microfluidic device for generation of large, precisely-defined, diverse lipid nanoparticle libraries for screening LNP formulations. Problem: Lipid nanoparticles (LNPs) have broad applications such as delivery agents for gene editing cargo, immunotherapies, and many clinical applications. The structures of the lipid components of an LNP, their relative...
Published: 4/17/2026   |   Updated: 4/17/2026   |   Inventor(s): Michael Mitchell, David Issadore, Andrew Hanna
Keywords(s): Bioengineering, Drug Delivery, Gene Editing, Gene Therapy, Immunology, Immunotherapy, Microfluidics, Nanotechnology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Hardware & Components, Technology Classifications > Robotics
An Accessible and Automated Device to Diagnose Nerve and Muscle Disorders
A device consisting of electrode patches, a control box, and software for automated nerve conduction studies. Problem: Nerve conduction studies are essential tools in the diagnosis and management of nerve and muscle disorders. However, current diagnostic tools rely heavily on trained physicians, manual testing protocols, and the precise placement of...
Published: 4/8/2026   |   Updated: 4/8/2026   |   Inventor(s): Josh Baxter, Flavia Vitale, Margaret (Maggie) Wagner, Quinn Tate
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Bioengineering, Neurodegenerative Diseases, Neurology, Orthopedics, Software
Category(s): Technology Classifications > Hardware & Components, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Testing & Measurement
Reflective Polymer Coating For Microscale Electronic Communication
A polymer coating which allows a device’s electrical activity to be optically transmitted based on its transparency. Problem: Existing wireless microscale communication platforms, such as radio-frequency antennas and micro-LEDs, are limited in their large footprint requirements relative to the chip size, have challenging integration pathways...
Published: 3/16/2026   |   Updated: 3/16/2026   |   Inventor(s): Marc Miskin, Matthew Campbell
Keywords(s): Electronic Materials, Nanotechnology, Platform Technology
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components, Technology Classifications > Materials
Tiny “Light-Twisting” Lasers For Faster, More Secure Encryption Keys
Quantum on-chip device that powers future ultra-secure, high-speed digital communication by encoding more information into single particles of light. Problem: Quantum key distribution (QKD) is a new way to create secure communication systems; however, it is limited to sending only a small amount of information at a time. Most current systems use qubits,...
Published: 2/8/2026   |   Updated: 2/8/2026   |   Inventor(s): Liang Feng, Yichi Zhang
Keywords(s): Electronic Materials
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components
Mechanically Tunable Engineered Heart Tissue Platform
Next-generation engineered heart tissue platform that enables precise tuning of mechanical properties of microenvironment to study the structure, development, and function of cultured cells or human-derived cardiac tissues. Problem: Engineering heart tissue (EHT) platforms have the potential to study heart physiology, disease pathology, and therapeutic...
Published: 1/30/2026   |   Updated: 1/30/2026   |   Inventor(s): Kenneth Margulies, Benjamin Lee, Nesrine Bouhrira
Keywords(s): Bioengineering, Cardiovascular, Drug Target, Platform Technology
Category(s): Technology Classifications > Hardware & Components, Technology Classifications > Research Tools & Reagents, Technology Classifications > Testing & Measurement
Instant, Calibration-Free Blood-Flow Measurement With A Single Optical Snapshot
A single-frame, multi-exposure time optical method enabling accurate extraction of absolute speckle decorrelation time and optimized for recovery of absolute deep-tissue blood flow. Problem: Accurately recovering absolute speckle decorrelation time without the use of calibration or complex instrumentation is challenging. For the use case of monitoring...
Published: 1/8/2026   |   Updated: 1/8/2026   |   Inventor(s): Arjun Yodh, Wesley Baker, Joseph Majeski, Rodrigo Menezes Forti
Keywords(s): Bioengineering, Cardiovascular, Electronic Materials, Gastroenterology, Internet of Things, Nephrology and Urology, Neurology, Oncology, Ophthalmology, Optics & Photonics , Platform Technology, Surgery
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Diagnostics, Technology Classifications > Digital Health, Technology Classifications > Hardware & Components, Technology Classifications > Imaging, Technology Classifications > Research Tools & Reagents, Technology Classifications > Medical Devices, Technology Classifications > Testing & Measurement
Commercially Scalable Quantum Internet Architecture
A hybrid photonic system that enables quantum networking to scale across existing fiber infrastructure. Problem: Developing a commercially scalable quantum internet—one that can substantially reduce deployment costs by using existing fiber networks—is challenged by the fact that current quantum systems remain isolated laboratory platforms...
Published: 1/13/2026   |   Updated: 12/15/2025   |   Inventor(s): Liang Feng, Yichi Zhang, Robert Broberg, Jonathan Smith
Keywords(s): Electronic Materials, Optical/Photonic Architecture, Optics & Photonics 
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components, Technology Classifications > Materials
Electronic-Photonic Quadrature Delay-Locked Oscillator (DLO) For Efficient High-Speed Clock Generation And Distribution
A Quadrature Delay-Locked Oscillator that caters to increasing multi-GHz and multi-phase clock demands in systems such as time-interleaved architectures. Problem: The unrelenting growth of artificial intelligence (AI) requires advancements in high-performance hardware capable of delivering high-speed clock generation and distribution. These improvements...
Published: 10/29/2025   |   Updated: 10/29/2025   |   Inventor(s): Firooz Aflatouni, Henry Love
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Electronic Materials, Optics & Photonics 
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components
Programmable, All-Optical, Photonic Architecture for Nonlinear Operations With Field Programmable Chips
A field programmable photonic architecture that enables nonlinear computation making it suitable to use the advantages of photonics in the field of AI. Problem: Reconfigurable computing with field-programmable devices offers the flexibility to adapt hardware to changing workloads, and integrating photonics into these systems enables fast, energy-efficient...
Published: 1/13/2026   |   Updated: 8/4/2025   |   Inventor(s): Liang Feng, Tianwei Wu
Keywords(s): Electronic Materials, Optical/Photonic Architecture, Optics & Photonics 
Category(s): Technology Classifications > Hardware & Components, Technology Classifications > Materials
Physical Neural Network for Fast, Scalable, and Power-Efficient Machine Learning Computation
A physical embodiment of a locally-learning neural network, which learns faster than current CPU-based nets. Problem: Machine learning is a ubiquitous tool that has found uses in engineering, science, and medicine. Neural networks are some of the most powerful machine learning algorithms, but they train very slowly when they become large. This hampers...
Published: 9/26/2025   |   Updated: 10/24/2024   |   Inventor(s): Samuel Dillavou, Douglas Durian, Andrea Liu, Menachem (Nachi) Stern, Marc Miskin
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Data Science, Electronic Materials, Internet of Things, Nanotechnology, Software
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components
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