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Chemical Modifications of Substrates Using Zwitterionic-Functionalized Dendrimers
Novel platform for biomaterials development with advanced physiological properties BACKGROUND: The need for improved biomaterials is a continuous challenge in the clinical field. Extended physiological circulation times, reduced immune responses, and lowered cytotoxicity are a few parameters crucial for therapeutic and diagnostic biomaterials. ...
Published: 3/24/2026   |   Updated: 3/23/2026   |   Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
Functionalized Dendrimers with Regioselective Reactivity
Novel compositions of zwitterionic dendrimers and derived polymers BACKGROUND: There is a strong need for new classes of reactive reagents for the generation of novel materials with pre-defined characteristics. Here, new compounds can be generated employing properties associated with zwitterions, dendrimers, or combination materials. TECHNOLOGY...
Published: 3/24/2026   |   Updated: 3/23/2026   |   Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics
Liquid Biopsy Detection of TF-Ag-α-Positive Cancer-Associated Exosomes
A liquid biopsy assay detecting TF-Ag-α–positive tumor-derived exosomes for cancer screening, early detection and treatment monitoring. Background: Cancer diagnostics are rapidly evolving as early detection and treatment monitoring are critical to improving patient outcomes. Traditional methods such as imaging and tissue biopsies are...
Published: 3/23/2026   |   Updated: 3/23/2026   |   Inventor(s): Grace Dy, Yun Wu, Kate Rittenhouse-Olson
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Engineering, Technology Classifications > Medical Devices, Technology Classifications > Sensors
Improving the sensitivity and range of detection with ligation of DNA nanoswitches
This technology uses enzymatic ligation in DNA nanoswitches to detect very short or rare DNA and RNA sequences with high sensitivity, amplifying signals by recycling targets so even single molecules can be identified for diagnostics and research. Background: Nucleic acid detection is a cornerstone of modern molecular biology, diagnostics, and biotechnology,...
Published: 3/11/2026   |   Updated: 3/11/2026   |   Inventor(s): Kenneth Halvorsen, Jibin Punnoose, Vinod Morya
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
A 3D printable mini-gel electrophoresis system and methods for use
This technology is a low-cost, 3D printable mini-gel electrophoresis system with built-in electrodes, enabling rapid, portable DNA analysis using battery power—ideal for education, fieldwork, and labs with limited resources. Background: Gel electrophoresis is a cornerstone technique in molecular biology, widely used for the separation and analysis...
Published: 3/9/2026   |   Updated: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Andrew Hayden, Vinod Morya
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics
Expanding DNA nanoswitch utility with detection by aptamers
This technology integrates aptamers into DNA nanoswitches, enabling sensitive detection of a wide range of biomolecules—including proteins and small molecules—for use in diagnostics, research, and biosensing applications. Background: Molecular detection technologies are foundational in fields such as diagnostics, biomedical research,...
Published: 3/9/2026   |   Updated: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
Methods for detecting RNA modifications with DNA nanoswitches
This technology uses DNA nanoswitches to directly and specifically detect RNA modifications, allowing simultaneous identification of multiple modifications in their natural sequence context for research, diagnostics, and drug discovery applications. Background: RNA modifications, such as methylation, play critical roles in gene regulation, cellular...
Published: 3/9/2026   |   Updated: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Iranna Todkari, Andrew Hayden
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Design and Synthesis
Analysis of Immune Repertoire with Fluorogenic Probes
­ ​Rapid analysis of T cells for the diagnosis of diseases in which the T cell repertoire is altered. Cells are distributed in aqueous droplets and their T cell receptor mRNAs are amplified in presence of “sloppy” molecular beacons. The melt profiles of molecular beacons in thousands of droplets reveals the T cell repertoire of...
Published: 3/16/2026   |   Updated: 2/9/2026   |   Inventor(s): Sanjay Tyagi, Fred Kramer, Salvatore Marras, Ryan Dikdan, Stan Kwang
Keywords(s):  
Category(s): Technology Classifications > Diagnostics
DEVICE FOR ORAL FLUID COLLECTION CONSISTING OF ABSORBANT MATERIAL AND NESTED TUBES REQUIRING CENTRIFUGATION
This is a simple, low-cost device using absorbent material and nested tubes to collect clean, mucous-free oral fluid samples by centrifugation, making sample collection easier, more hygienic, and affordable for labs and research. Background: Oral fluid collection is an essential process in various fields, including clinical diagnostics, biomedical...
Published: 2/13/2026   |   Updated: 2/6/2026   |   Inventor(s): Aaron Glass
Keywords(s): saliva, Salivary biomarkers, specimen collection, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Medical Devices, Technology Classifications > Diagnostics
Instant, Calibration-Free Blood-Flow Measurement With A Single Optical Snapshot
A single-frame, multi-exposure time optical method enabling accurate extraction of absolute speckle decorrelation time and optimized for recovery of absolute deep-tissue blood flow. Problem: Accurately recovering absolute speckle decorrelation time without the use of calibration or complex instrumentation is challenging. For the use case of monitoring...
Published: 1/8/2026   |   Updated: 1/8/2026   |   Inventor(s): Arjun Yodh, Wesley Baker, Joseph Majeski, Rodrigo Menezes Forti
Keywords(s): Bioengineering, Cardiovascular, Electronic Materials, Gastroenterology, Internet of Things, Nephrology and Urology, Neurology, Oncology, Ophthalmology, Optics & Photonics , Platform Technology, Surgery
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Diagnostics, Technology Classifications > Digital Health, Technology Classifications > Hardware & Components, Technology Classifications > Imaging, Technology Classifications > Research Tools & Reagents, Technology Classifications > Medical Devices, Technology Classifications > Testing & Measurement
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