Search Results - shiming+zhang

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A tool and method for precise, high-throughput spatial mapping of proteins across whole tissue samples. Background: Spatial proteomics enables delineation of spatial localization of proteins within cells and tissues. This ability to identify and study the relative location and quantification of one or more proteins, whether ones that are endogenously...

Published: 8/21/2024 | Inventor(s): Jun Qu, Ming Zhang, Min Ma

Keywords(s): Featured, Technologies

Category(s): Campus > University at Buffalo, Technology Classifications > Bioinformatics

Method for 3D Nonlinear Structured Illumination Super-resolution Imaging

Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...

Published: 4/3/2023 | Inventor(s): Leilei Peng, Yu Li, Han Zhang

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

Helical Sulfono-γ-AApeptide Antagonize β-Catenin Signaling

Competitive Advantages Potent, specific, and cell permeable to target intracellular PPIs High stability against enzymatic degradation More effective than other peptides at antagonizing Wnt/β-catenin signaling Summary Protein-protein interactions (PPIs) are vital to the survival of cancer cells and are therefore a good target for anti-cancer...

Published: 7/17/2023 | Inventor(s): Jianfeng Cai, Peng Sang, Yan Shi, Haitao Ji, Min Zhang

Keywords(s): Cancer, Cancer Treatment Leukemias, Cancer Treatment Lymphomas, Peptides, Therapeutics

Category(s): Technology Classifications > Cancer

2021-046 SOFT BIOSENSORS BASED ON BIODEGRADABLE GELATIN METHACRYLOYL (GELMA)

UCLA researchers in the department of Bioengineering have developed a soft biodegradable hydrogel that is capable of functioning in biocompatible biosensors.BACKGROUNDBiosensors are physical devices that combine a physiochemical detector with a biological component. The use of biosensors has revolutionized a number of industries including the medical...

Published: 9/5/2023 | Inventor(s): Ali Khademhosseini, Shiming Zhang, Zhikang Li

Keywords(s): Biosensor

Category(s): Medical Devices

2021-100 HIGH-THROUGHPUT DISEASE BIOMARKER SCREENING WITH HIGH-TRANSCONDUCTANCE ORGANIC ELECTROCHEMICAL TRANSISTOR ARRAYS

Researchers in UCLA’s Department of Bioengineering have developed a transistor-based biosensor for high-throughput disease biomarker screening applications: this minimally invasive sensor features high sensitivity and robustness to competing biomarkers, potentially enabling a next-generation mobile point of care (POC) device.BACKGROUNDMolecular...

Published: 7/19/2023 | Inventor(s): Shiming Zhang, Ali Khademhosseini

Keywords(s): Biomarker

Category(s): Medical Devices

Automated Glomerular Segmentation Pipeline for 3D MRI

Recent studies conclude that a strong correlation exists between the numbers of glomerular in the kidney and renal diseases. These findings generate great interest in accurately counting glomeruli. Traditionally, the glomerulus is counted using histological sections, which have several limitations. First, histology based counting relies on techniques...

Published: 2/23/2023 | Inventor(s): Teresa Wu, Min Zhang

Keywords(s): Algorithm Development, Imaging, Materials and Electronics, Mechanical and Manufacturing, Medical Devices and Imaging, Modeling, Nephrology, Networks, IT, Software and Communication

Category(s): Computing & Information Technology

Fiber-Optic Interferometric Sensors

Executive SummaryFiber-optic sensors using optical interferometers have application for sensing a variety of parameters such as acoustic waves, strain, temperature, and refractive index. The technology is a demodulation method that does not require laser wavelength tuning. The technology provides adaptive ultrasound detection with improved accuracy...

Published: 2/17/2023 | Inventor(s): Ming Han

Keywords(s):

Category(s): Analytical Instruments, Devices, Test and Measurement

A System For Visual Presentation Of Concepts From Ontology And Text Documents

PAGE TITLEOverviewPAGE SUMMARYA system lets a user click on a location of a brain model to explore neuroscience ontology terms related to the location. The user can further explore the related terms and related documents through a visualization interface and learn new concept or document relationships derived from the ontology and annotated document...

Published: 7/24/2024 | Inventor(s): Yuan An, Xia Lin, Mi Zhang, Yue Shang

Keywords(s):

Category(s): Computing, Software, Analytics & Information Technology, Computing, Software, Analytics & Information Technology > Computing: Algorithms, Computing, Software, Analytics & Information Technology > Computing: Contextual Analytics, Computing, Software, Analytics & Information Technology > Computing: Data Mining, Computing, Software, Analytics & Information Technology > Computing: Databases

Nest DNN, a Pruning-and-Recovery Paradigm for Deep Neural Networks

Executive SummaryNeural networks are employed ubiquitously in our lives today. Found in applications such as video games, face identification, autonomous vehicles navigation, and medical diagnostic tools, these algorithms require a hefty amount of computer resources. In instances where resource demand is greater than availability, accuracy and computational...

Published: 8/20/2022 | Inventor(s): Mi Zhang, Biyi Fang, Xiao Zeng

Keywords(s):

Category(s): Computer Software, Data Processing/Analysis, Informatics

Mobile Phone App for Real Time Pill Recognition

Executive SummaryThe ability to quickly and reliably be able to identify both prescription and non-prescription medications is not only important for a patient and his caretaker, but also important for pharmacists, nurses, and law enforcement agents. Despite unique FDA-approved identifiers for each pill, distinguishing the differences can be difficult...

Published: 8/20/2022 | Inventor(s): Mi Zhang, Kai Cao, Xiao Zeng

Keywords(s):

Category(s): Medical, Computer Software, Pharmaceutical

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