Search Results - sanjay+malhotra

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Combination therapy for the treatment of triple negative breast cancer
Summary Researchers at OHSU have discovered a novel combination therapy for triple negative breast cancer, which increases immune responses, causes tumor regression and improves survival in animal models. Technology Overview Triple negative breast cancer (TNBC) represents one of the most aggressive forms of all breast cancer subtypes with a very...
Published: 9/17/2024   |   Inventor(s): Sanjay Malhotra, Lisa Coussens, Dhanir Tailor, Sushil Kumar, Arpit Dheeraj
Keywords(s): Therapeutics, Therapeutics - Cancer
Category(s): Therapeutics
Treatment of Prostate Cancer Using Anti-androgen Small Molecules
Abstract: Castrate-resistant prostate cancer (CRPC) is characterized by androgen-independent cancer cells that have adapted to the depletion of hormones and continue to grow. Abnormal androgen receptor signaling is known to drive advanced castrate-resistant prostate cancer. The small molecule compounds of this invention are antiandrogens that target...
Published: 4/8/2024   |   Inventor(s): Jane Trepel Neckers, Yeong Kim, Sunmin Lee, Vineet Kumar, Sanjay Malhotra
Keywords(s): Antiandrogen, castrate resistant, CRPC, PROSTATE CANCER, small molecule, steroid hormone receptor.
Category(s): Application > Therapeutics, Collaboration Sought > Licensing, TherapeuticArea > Oncology