Search Results - shanshan+(melissa)+he

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Benzofuranoindoline-Containing Fungal RiPP-Derived Anticancer Compounds

Benzofuranoindoline-containing fungal RiPP-derived compounds and analogs, plus pharmaceutical compositions, and administration methods for treating cancers, including leukemia. Problem: The disclosure targets diseases and disorders where new therapeutic compounds are needed, including cancers such as leukemia. Fungal ribosomally synthesized and post-translationally...

Published: 4/16/2026 | Updated: 4/16/2026 | Inventor(s): Xue Sherry Gao, Hans Renata, Qiuyue Nie

Keywords(s): Oncology, Small Molecule

Category(s): Technology Classifications > Therapeutics

Architecture and Level 2 Variable Power Control Scheme (Case No. 2013-146)

Summary: UCLA researchers in the Department of Mechanical & Aerospace Engineering have developed a smart EV charging architecture that dynamically optimizes EV charging loads based on real-time grid capacity and limitations. Background: The rapid increase in electric vehicle (EV) adoption creates a critical need for robust and accessible charging...

Published: 4/7/2026 | Updated: 4/7/2026 | Inventor(s): Rajit Gadh, Ching Yen Chung, Chi Cheng Chu, Li Qiu

Keywords(s): Charge Carrier, charge collection, charge collection efficiency, charge extraction, charge sharing, charge summing, charged particle beams, charge-transfer, Electric Current, Electric Vehicle, electric vehicle charging, Electrical, Electrical Impedance, Electrical Load, Energy Harvesting Evaporation, EV battery cooling, grid efficiency, grid energy, Power distribution & grids, Rechargeable Battery, Rechargeable Battery Thermal Conductivity, Smart Grid, supercharger, Surface Charge, vehicle charging

Category(s): Electrical, Energy & Environment, Energy & Environment > Energy Efficiency, Energy & Environment > Energy Generation, Energy & Environment > Energy Storage, Energy & Environment > Energy Transmission

Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels

This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...

Published: 3/23/2026 | Updated: 3/23/2026 | Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays

Electrotherapy for dental implants

In Situ electrochemical repassivation therapy of titanium dental implants can restore corrosion resistance and enhance cellular biocompatibility. Invention Summary: Peri-implantitis affects up to 25% of dental implant patients and is a leading cause of implant failure, representing a global market burden exceeding $1B annually. Current treatments...

Published: 3/10/2026 | Updated: 2/20/2026 | Inventor(s): Georgios Kotsakis, Li Xie

Keywords(s):

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Dental

Impact energy assessment through data fusion

Reference #: 1733 The University of South Carolina is offering licensing opportunities for Impact energy assessment through data fusion. Background: When a material is subjected to external forces or internal stress, its internal structure gradually accumulates energy. In composite materials, for example, this process can result in fiber breakage...

Published: 4/24/2026 | Updated: 2/17/2026 | Inventor(s): Li Ai, Paul Ziehl

Keywords(s):

Category(s): Engineering and Physical Sciences

Assessment of impact localization and energy

Reference #: 1711 The University of South Carolina is offering licensing opportunities for Assessment of impact localization and energy. Background: When a material is subjected to external forces or internal stress, its internal structure gradually accumulates energy. In composite materials, for example, this process can result in fiber breakage...

Published: 3/25/2026 | Updated: 2/17/2026 | Inventor(s): Paul Ziehl, Li Ai

Keywords(s):

Category(s): Software and Computing

Regulating urea in infant nutrition to support early-life microbiome development and health

Synchronizing infant nutrition with early-life biology. Rutgers researchers propose replacing static infant nutrition with formulations inspired by human breast milk. Regulated urea delivery aligned with infant developmental needs and microbiome sustenance enables next-generation nutrition for infants. Invention Summary: Current infant nutritional...

Published: 3/10/2026 | Updated: 2/12/2026 | Inventor(s): Martin Blaser, Liisa Veerus, Maria Dominguez Bello, Melissa Woortman

Keywords(s):

Category(s): Technology Classifications > Food, Nutrition and Nutraceuticals

Dark Eye Harvester

This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...

Published: 2/9/2026 | Updated: 2/9/2026 | Inventor(s): A Departmental Work, Michael Brown

Keywords(s):

Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools

Method to Determine Quality of Mitochondrial Cargo in Extracellular Vesicles

A novel method that measures mitochondrial membrane potential in extracellular vesicles, providing a direct readout of mitochondrial quality and utility. Background: Studies have shown that EV-mediated intercellular communication is influenced, at least in part, by the mitochondrial cargo contained within EVs. This highlights the importance of rigorous...

Published: 4/16/2026 | Updated: 1/6/2026 | Inventor(s): Barbara Alevriadou, Zahid Manzar, Hans Minderman

Keywords(s): Biotechnology, Diagnostic, Healthcare, Pharmaceutical, Research Tool, Technologies, Therapeutic and Vaccines

Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays

Transgenic Mouse Model for Marfan Syndrome Research

Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...

Published: 12/23/2025 | Updated: 12/23/2025 | Inventor(s): Li Li, Shichao Wu, Jiawei Zhao

Keywords(s):

Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic

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