Search Results - shanshan+(melissa)+he

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Method to Determine Quality of Mitochondrial Cargo in Extracellular Vesicles

A novel method that measures mitochondrial membrane potential in extracellular vesicles, providing a direct readout of mitochondrial quality and utility. Background: Studies have shown that EV-mediated intercellular communication is influenced, at least in part, by the mitochondrial cargo contained within EVs. This highlights the importance of rigorous...

Published: 1/21/2026 | Inventor(s): Barbara Alevriadou, Zahid Manzar, Hans Minderman

Keywords(s): Biotechnology, Diagnostic, Healthcare, Pharmaceutical, Research Tool, Technologies, Therapeutic and Vaccines

Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays

Transgenic Mouse Model for Marfan Syndrome Research

Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...

Published: 12/23/2025 | Inventor(s): Li Li, Shichao Wu, Jiawei Zhao

Keywords(s):

Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic

Small Molecules That Expose HIV Env Sites To Trigger Targeted Immune Killing

This technology uses small molecules to bind HIV Env on infected cells, expose hidden sites, and trigger ADCC, enabling the immune system to kill cells that current therapies cannot reach. By improving antibody recognition and reducing infectious virus production, it provides a complementary approach that directly targets infected cells rather than...

Published: 12/1/2025 | Inventor(s): Amos Smith, Melissa Grenier-Davies, Andres Finzi, Jean-Philippe Chapleau, Shilei Ding

Keywords(s): HIV/AIDS

Category(s): Technology Classifications > Therapeutics, Technology Classifications > Vaccines

B Cell-Based Assay to Expand Antigen-Specific T Cells (UCLA Case No. 2025-288)

UCLA researchers from the Department of Medicine have developed a novel B cell-based assay to expand antigen-specific T cells, allowing for an efficient, patient-specific platform to generate tumor antigen-specific T cells. BACKGROUND: Adoptive T cell therapies have emerged as a promising strategy for cancer immunotherapy, enabling the expansion of...

Published: 11/6/2025 | Inventor(s): Yuanyuan Tong, Willy Hugo, Maureen Su, Melissa Lechner, Robert Prins

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

Self-restructuring platinum ternary nanoalloys for durable low temperature exhaust oxidation

This invention introduces self-restructuring platinum-based ternary nanoalloy catalysts that maintain high oxidation activity after hydrothermal aging. By alloying Pt with two transition metals, the catalyst delivers durable low-temperature exhaust oxidation with reduced precious metal use, supporting efficient CO, hydrocarbon, and NO oxidation for...

Published: 11/12/2025 | Inventor(s): Chuan Jian Zhong, Shiyao Shan, Shan Wang

Keywords(s): Technologies

Category(s): Campus > Binghamton University

Room-Temperature Silver-Copper Nanoalloy Inks for Low-Cost Flexible Electronics

This invention introduces silver-copper (AgCu) nanoalloy inks and pastes that sinter at room temperature, enabling low-cost, flexible, and energy-efficient printed electronics. The formulation maintains high conductivity, resists oxidation, and can be printed on heat-sensitive substrates like paper, polymers, and textiles without external heating, supporting...

Published: 11/12/2025 | Inventor(s): Chuan Jian Zhong, Richard Robinson, Shan Wang, Shan Yan, Guojun Shang

Keywords(s): Technologies

Category(s): Campus > Binghamton University

Room-Temperature Silver-Copper Nanoalloy Inks for Low-Cost Flexible Electronics

Published: 11/12/2025 | Inventor(s): Chuan Jian Zhong, Richard Robinson, Shan Wang, Shan Yan, Guojun Shang

Keywords(s): Technologies

Category(s): Campus > Binghamton University

An Edge-Native Trusted Intelligent Predictive Condition Monitoring System for Distributed Wind Systems

Overview of Technology An innovative edge-native trusted intelligent predictive condition monitoring system designed for distributed wind systems, enhancing operational efficiency, reducing maintenance costs, and improving cybersecurity. Background The distributed wind industry faces challenges such as remote turbine locations, inconsistent monitoring,...

Published: 1/27/2026 | Inventor(s): Eli Herrington, Gang Li, Sara Mouafik, William Mayfield, Doha Bounaim, Zachary Barbre

Keywords(s):

Category(s): Energy & Environmental

Lipid-Based Diagnostic for Minimally-Invasive Screening and Early Detection of Gynecologic Cancer

This invention is a non-invasive diagnostic for the screening and early detection of gynecologic cancers, including endometrial, cervical, and ovarian cancer, based on a lipid panel. It analyzes cervicovaginal lavages for key biomarkers that could ultimately be used a screening technology as a part of a well-woman exam to assess the risk of gynecologic...

Published: 9/22/2025 | Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics

Breakthrough Silver-Based Catalyst Delivers Platinum-Level Performance for Hydrogen Generation - Without the Platinum Price Tag

Title: Breakthrough Silver-Based Catalyst Delivers Platinum-Level Performance for Hydrogen Generation – Without the Platinum Price Tag This invention introduces a cost-effective, nano-engineered silver catalyst that achieves platinum-level hydrogen evolution performance in acidic media, with ~40× lower material cost and scalable synthesis....

Published: 11/12/2025 | Inventor(s): Chuan Jian Zhong, Shan Wang

Keywords(s): Technologies

Category(s): Campus > Binghamton University

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