Search Results - samuel+hasson

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Cotranslational Protein Expression System for High-throughput Screening
Reporter gene-based assays are used extensively in high-throughput screening (HTS) to identify chemical modulators of cellular pathways for drug discovery and development. However, such screening frequently results in a large number of false “hits” due to interactions of screened compounds with reporter proteins, producing confounding results. Thus,...
Published: 10/28/2024   |   Inventor(s): Chih-Chien (Ken) Cheng, Samuel Hasson, James Inglese
Keywords(s): AC4XXX, ACXXXX, AXXXXX, Coincidence, drug discovery, Drug Screening, High-throughput, High-throughput screen, HTS, REPORTER, reporter gene
Category(s): Collaboration Sought > Collaboration
2009-221 Small Molecule Modulators of Mitochondrial Protein Import (MitoBloCK1)
Small Molecule Modulators Of Mitochondrial Protein ImportSUMMARYUCLA researchers in the Department of Chemistry & Biochemistry have discovered a set of small molecules that modulate the protein translocation across the mitochondrial membranes, which in turn controls the assembly and function of the mitochondria.BACKGROUNDMitochondria are rod-shaped...
Published: 7/19/2023   |   Inventor(s): Carla Koehler, Samuel Hasson
Keywords(s): Oncology (Small Molecules, Peptides and Antibodies), Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Oncology > Oncology (Small Molecules)