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Search Results - high-throughput+screen
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Cotranslational Protein Expression System for
High-throughput Screen
ing
Reporter gene-based assays are used extensively in
high-throughput screen
ing (HTS) to identify chemical modulators of cellular pathways for drug discovery and development. However, such screening frequently results in a large number of false “hits” due to interactions of screened compounds with reporter proteins, producing confounding results. Thus,...
Published: 10/28/2024
|
Inventor(s):
Chih-Chien (Ken) Cheng
,
Samuel Hasson
,
James Inglese
Keywords(s):
AC4XXX
,
ACXXXX
,
AXXXXX
,
Coincidence
,
drug discovery
,
Drug Screening
,
High-throughput
,
High-throughput screen
,
HTS
,
REPORTER
,
reporter gene
Category(s):
Collaboration Sought > Collaboration
Inhibitors of Glucose Kinases: Update 2-27-2019
Reference #: 01401 The University of South Carolina is offering licensing opportunities for Monosaccharide Amine and 3-Nitro-2-Phenyl-2H-Chromene Based Inhibitors of Glucose Kinases Background: When a kissing bug bites a human, they can be infected with a Kinetoplastid parasite such as Trypanosoma cruzi (T. cruzi). A need exists for new drugs that...
Published: 9/4/2022
|
Inventor(s):
Edward D'antonio
Keywords(s):
African Sleeping Sickness
,
Chagas' Disease
,
drug discovery
,
Glucokinase
,
Glucose Kinases
,
Glycolysis
,
Hexokinase
,
High-Throughput Screen
,
HTS
,
inhibitor
,
Inhibitor constant (Ki)
,
Leishmanisis
,
Parasite
,
Parasitic Infections
,
Pentose Phosphate Pathway
,
Trypanosoma brucei
,
Trypanosoma cruzi
,
Trypanosome
Category(s):
Chemistry and Biochemistry
,
Biomedical and Life Sciences