Search Results - osteogenesis

2 Results Sort By:
WNT1-Induced Secreted Protein-1 Knockout Mouse Model
WNT1-induced secreted protein-1 (WISP1) is expressed at high levels in osteoblasts and their precursors. WIPS1 plays an important role in various aspects of bone formation. Scientists at the NIH generated Wisp1-deficient (Wisp1-/-) mice. Deletion of Wisp1 resulted in a decrease in bone mineral density, total bone volume, bone thickness, and biomechanical...
Published: 12/26/2024   |   Inventor(s): Azusa Maeda, Mitsuaki Ono, Marian Young
Keywords(s): DEFICIENT, Generation, Mice, OSTEOGENESIS, VAXXXX, VPXXXX, WISP1, WIXXXX, XCXXXX, XEXXXX, YCXXXX
Category(s): TherapeuticArea > Ophthalmology, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, TherapeuticArea > Immunology, Application > Research Materials, TherapeuticArea > Geriatrics, Application > Diagnostics
Novel agents and methods for treating metabolic bone disorders and other conditions
Project ID: D2014-15IP Status: Provisional patent #62/115,786Invention Description: Methods of generating and administering digestion products of FDA-approved low acyl gellan gum (LA-GAGR) to produce mega-GAGR, midi-GAGR, and mini-GAGR and administration thereof. Applications: Compositions comprising midi- and/or mini-GAGR have been shown to be useful...
Published: 8/3/2022   |   Inventor(s): Dong Shik Kim, Joshua Park
Keywords(s): Bone Cell Formation, Metabolic Bone Diseases, Osteogenesis, Osteoporosis
Category(s):