Search Results - natural+killer+cells

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Oleate-Mediated Enhancement of Human Natural Killer Cell Function (UCLA Case No. 2024-180)
UCLA researchers in the Department of Microbiology, Immunology and Molecular Genetics have discovered a novel approach to boost natural killer cell function through fatty acid supplementation. BACKGROUND: Natural killer (NK) cells are part of the body’s defense system that hunts down and kills cells that are infected by viruses or have become...
Published: 11/15/2024   |   Inventor(s): Timothy O'Sullivan
Keywords(s): fatty acids, immune defense, immune disorders, Immunology, natural killer cells, nk cells
Category(s): Therapeutics > Immunology And Immunotherapy
3-o-sulfo-galactosylceramide Analogs as Activators of Type II Natural Killer T (NKT) Cells to Reduce Cancer Metastasis to the Lung
Abstract: Lung metastases are a sign of widespread cancer with poor survival rate. Lung malignancies can originate from almost any cancer type spread via the blood stream. Most common lung metastases are from melanoma, breast cancer, bladder cancer, colon cancer, prostate cancer, neuroblastoma, and sarcoma. Living more than 5 years with lung metastases...
Published: 8/5/2024   |   Inventor(s): Lise Pasquet, Jay Berzofsky, Amy Howell, Masaki Terabe, Kaddy Camara
Keywords(s): 3-o-sulfo-galactosylceramide Analogs, Berzofsky, C24:2, Immunotherapy, lung cancer, Metastasis, Natural Killer cells, NKT cells, Sulfatide Analogs, T Cells
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Immunology
Therapeutic Nanoparticles for Non-Viral Drug Delivery to Natural Killer Cells
Transfects Natural Killer Cells Without the Use of VirusesThese nanoparticles enable the delivery of nucleic acids or drugs to immunosuppressed natural killer (NK) cells to restore their cytotoxic functions in tumor microenvironments. Globally, cancer causes one of every six deaths, with the number of new cases expected to rise to 23.6 million per year...
Published: 6/27/2021   |   Inventor(s): Blanka Sharma, Isaac Adjei
Keywords(s): Drug Delivery, Immunotherapy, MNO2, Nanoparticle, Natural Killer Cells, nucleic acid delivery
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Drug Delivery