Search Results - nk+cells

2 Results Sort By:
Oleate-Mediated Enhancement of Human Natural Killer Cell Function (UCLA Case No. 2024-180)
UCLA researchers in the Department of Microbiology, Immunology and Molecular Genetics have discovered a novel approach to boost natural killer cell function through fatty acid supplementation. BACKGROUND: Natural killer (NK) cells are part of the body’s defense system that hunts down and kills cells that are infected by viruses or have become...
Published: 10/7/2024   |   Inventor(s): Timothy O'Sullivan
Keywords(s): fatty acids, immune defense, immune disorders, Immunology, natural killer cells, nk cells
Category(s): Therapeutics > Immunology And Immunotherapy
Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7
A highly efficient method to genetically modify natural killer (NK) cells to induce expression of high affinity CD16 (HA-CD16) through mRNA electroporation, to potentiate NK cell-mediated antibody-dependent cellular cytotoxicity (ADCC). ADCC is mediated by CD16+ NK cells following adoptive NK cell transfer, but most humans express CD16 which has a relatively...
Published: 10/28/2024   |   Inventor(s): Mattias Carlsten, Richard Childs
Keywords(s): ADCC, antibodies, ANTIBODY, CBXXXX, CD16, ex vivo, Listed LPM Vathyam as of 4/15/2015, monoclonal, NK, NK Cells, Patent Category - Biotechnology, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, TRANSFECTION, TUMORS, VCXXXX, WJXXXX, XEXXXX, YAXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology