Search Results - berzofsky

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3-o-sulfo-galactosylceramide Analogs for Targeting Lung Metastases
Summary: Lung metastases represent a major clinical challenge in advanced cancer, with poor survival rates and no effective therapies to prevent their development. Researchers at the National Cancer Institute (NCI) have developed C24:2, a first-in-class synthetic 3-O-sulfo-galactosylceramide analog. After lysosomal processing by dendritic cells, C24:2...
Published: 9/15/2025   |   Inventor(s): Lise Pasquet, Jay Berzofsky, Amy Howell, Masaki Terabe, Kaddy Camara
Keywords(s): 3-o-sulfo-galactosylceramide Analogs, Berzofsky, C24:2, Immunotherapy, lung cancer, Metastasis, Natural Killer cells, NKT cells, Sulfatide Analogs, T Cells
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Immunology
Biomarker Analysis Software for High-Throughput Diagnostic Multiplex Data
Abstract: Extracellular vesicles (EVs) are lipid bilayer-enclosed particles that are released from cells. EVs may contain proteins derived from their cells of origin with the potential as diagnostic biomarkers indicating the state of the cells when released. However, due to their small size (50-1000nm), the methods currently used to phenotype EVs have...
Published: 4/22/2025   |   Inventor(s): Joshua Welsh, Jennifer Jones, Jay Berzofsky
Keywords(s): Berzofsky, Biomarker, EV, Extracellular Vesicles, High-throughput, Jones, Lipid Bilayer-Enclosed Particles, software
Category(s): Application > Software / Apps, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing