Search Results - m+denton

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Unmet Need: Accidental Deaths due to Benzodiazepines, Opiates, and Combined Benzodiazepine/Opiate Overdoses are Epidemic The use of opiates combined with benzodiazepines is ever-increasing. A study evaluating the prescription patterns between 2002 and 2014 reported that the annual number of patients receiving benzodiazepines increased 31 percent...

Published: 4/28/2023 | Inventor(s): John White, Travis Denton

Keywords(s):

Category(s): Technologies > Health & Well-being > Addiction, Technologies > Health & Well-being > Global Human and Animal Health, Technologies > Health & Well-being > Pharmaceutical

Silver-Silver Sulfide Reference Electrode

This invention is a new reference electrode that was prepared by anodizing (electrochemically oxidizing) silver metal in a sodium sulfide solution (SSSE). This results in a silver metal wire coated with silver sulfide. The electrode is extremely stable. The measured potentials for SSSE versus SSCE during two experiments in 1 molar KCl in air were 0.883...

Published: 8/1/2024 | Inventor(s): Dominic Gervasio, Kalin Denton, Gil-Pyo Kim, Vlad Sasaran, Alexis Gray

Keywords(s):

Category(s): Technology Classifications > Sensors & Controls > Chemical & Gas

SAHMI: Microbiome-based screening method for cancer and other diseases

Screening methodology and principle data identifying differences in microbiome diversity from disease state in pancreatic cancer Invention Summary: The microbiome plays an essential role in the prognosis and progression of disease and health, as seen in cancers like pancreatic cancer. Pancreatic cancer is rising in majority of cancer...

Published: 8/8/2022 | Inventor(s): Subhajyoti De, Bassel Ghaddar

Keywords(s): Anti-cancer, Bioinformatics, Biomarkers, Cancer biomarkers

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Cancer

Novel Compounds in Treating Autophagy-Related Pathologies

Project IDs: D2015-09 and D2016-81 Background: Autophagy is a self-degradation process of cellular organelles that helps defend against metabolic stress, maintain metabolic equilibrium, arbitrate cell fate decisions, and safeguard genomic stability. Deficient autophagy has been associated with over 100 diseases, and experimental enhancement of autophagy...

Published: 5/9/2024 | Inventor(s): Kenneth Hensley, Travis Denton

Keywords(s): ALS, Alzheimer's, Autophagy, Lanthionine Ketimine, Parkinson's

Category(s): Neuroscience

Novel agents for smoking and tobacco cessation

AbstractNicotine is the molecule responsible for the psychopharmacological effects and the addictive properties of tobacco use and cigarette smoking. Researchers at Washington State University have developed an orally-available nicotine derivative that can be prescribed for the cessation of cigarette smoking and tobacco use. It specifically inhibits...

Published: 5/25/2023 | Inventor(s): Philip Lazarus, Travis Denton, Gang Chen, Pramod Srivastava, Alec Wynd, Zuping Xia, Christy Watson

Keywords(s):

Category(s): Technologies > Health & Well-being > Biotechnology, Technologies > Health & Well-being > Chemistry, Technologies > Health & Well-being > Pharmaceutical, Technologies > Health & Well-being > Global Human and Animal Health

Efficient & Broadband Even-Order Harmonic Multiplication in Standard CMOS

A novel technique to realize highly-efficient passive multipliers in a standard CMOS process is demonstrated to efficiently generate even-order harmonics while simultaneously suppressing odd-order harmonics over broad-bandwidths. This is achieved by improving the cutoff frequency (fT) well beyond a THz. The higher fT combined with proposed nonlinearity...

Published: 4/26/2019 | Inventor(s): Kenneth O, Zeshan Ahmad

Keywords(s): Devices, Electronics, Engineering & Physical Sciences, Imaging, Optics & Photonics, Semiconductor, MEMS & Nanotechnology, Signal Processing, Wireless

Category(s): Communications

Design and Synthesis of a New Class of G-Quadruplex Binding Ligands for the Treatment of Cancer

This technology identifies new chemical entities (NCEs) that, according to FRET assay, target the G-quadruplex secondary DNA structure. The disclosed NCEs possess structural features with side chains that may improve potency with specificity over previously reported c-Myc suppressors. The Hurley lab previously discovered that stabilization of a specific...

Published: 11/16/2023 | Inventor(s): Laurence Hurley, Biswanath De, Venkateshwar Chappeta, Tracy Brooks, Vijay Gokhale, Cristina Beman, Heather Perry

Keywords(s):

Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics

Compounds Targeting on ABC Transporter-mediated Multidrug Resistance from TCM

Invention Reference: 11/MED/424 The ability of cancer cells to acquire resistance to multiple drugs, termed multidrug resistance (MDR), is often mediated by overexpression of ATP-binding cassette (ABC) transporters that remove substrates out of the cell against a concentration gradient. Among 48 human ABC transporters discovered, three, namely P-glycoprotein...

Published: 12/7/2020 | Inventor(s): Ge Lin, Kin Wah Kenneth To, Stella Chai, Yang Ye, Liang Ma, Chun Ping Tang

Keywords(s):

Category(s): Therapeutics

Discovery of a Recurrent Transforming Fusion Gene in Nasopharyngeal Carcioma (NPC)

Non-confidential abstract Nasopharyngeal carcinoma (NPC) is a distinct type of head and neck cancer which is prevalent in Southern China, Southeast Asia and North Africa. The development and stepwise progression of NPC involve accumulation of multiple gross genetic changes during the clonal expansion of EBV-infected nasopharyngeal epithelial cell population....

Published: 7/19/2021 | Inventor(s): Kwok Wai Lo, Ka Fai To, Tin Yun Grace Chung, Wai Ming Lung

Keywords(s):

Category(s): Therapeutics

Micro Faraday-Element Array Detector for Ion Mobility Spectroscopy

The novel ion mobility spectrometry (IMS) includes a drift tube having a collecting surface covering a collecting area at one end of the tube. The surface comprises a plurality of closely spaced conductive elements on a non-conductive substrate, each conductive element being electrically insulated from each other element. A plurality of capacitive transimpedance...

Published: 3/12/2024 | Inventor(s): M Denton, Roger Sperline, Christopher Gresham, Phillip Rodacy

Keywords(s):

Category(s): Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry

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