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Design and Use of Multi-targeting DNA Nanoswitches for Increased Sensitivity Detection of Long RNAs

This technology provides a novel method for detecting COVID-19 and potentially other virus-based diseases. Background: The COVID-19 pandemic created an unprecedented need for large scale diagnostic testing. Unfortunately, the pandemic also created a number of challenges for traditional in vitro diagnostic techniques. These challenges include reagent...

Published: 4/14/2025 | Inventor(s): Kenneth Halvorsen

Keywords(s): detection, DNA nanoswitches, Sensitivity, Technologies

Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > COVID-19, Technology Classifications > Diagnostics, Technology Classifications > Research Tools and Reagents

Ophthalmoscopic Device and Method for Capturing Images using the Same

The invention is a low-cost, portable in-vivo confocal ophthalmoscope (PICO) designed to capture microscopic images of the anterior segment of the eye and external eye structures without direct contact. The device is compact, lightweight, and capable of providing high-resolution imaging for real-time diagnostics. This ophthalmoscope can attach to standard...

Published: 4/14/2025 | Inventor(s): Dongkyun Kang, Kenneth Marcelino, Momoka Sugimura, Jaya Chidambaram

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Imaging & Optics > Ophthalmology, Technology Classifications > Healthcare Portfolios > Ophthalmology

Ribonuclease-responsive DNA Nanoswitches

A DNA nanoswitch that provides a simple mix-and-read methodology to detect RNases (ribonucleases) in a biological sample. Background: RNases are involved in many biological processes including neurotoxicity, genome replication and maintenance, immune-suppression, and antitumor activity. RNase inhibitors are also potential drug candidates and biomarkers...

Published: 4/1/2025 | Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran

Keywords(s): DNA, RNA, RNA-switch

Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Technology Classifications > Diagnostics

Flexible heat exchange system for maintaining patient core body temperature during medical procedures

A flexible, self-regulating heat exchange pad maintains patients’ body temperature during medical procedures. Adhesive, conforming pads with built-in heaters ensure even heat distribution, prevent overheating, and avoid pressure sores without mechanical restraints. Background Maintaining patients’ core body temperature during medical...

Published: 3/3/2025 | Inventor(s): Kenneth Diller, Sepideh Khoshnevis, Brian Patrick, Patrick Brown

Keywords(s):

Category(s): Life sciences > Medical technology

COLD SINTERED MXENE CERAMICS

PAGE SUMMARY This technology introduces a novel method for integrating 2D materials into ceramics without high-temperature degradation, enhancing their electrical and mechanical properties. It was jointly developed by leading researchers Yury Gogotsi at Drexel University and Clive Randall at Penn State University and is available for licensing. Nanocomposites...

Published: 2/20/2025 | Inventor(s): Yury Gogotsi, Babak Anasori, Benjamin Legum, Pavel Lelyukh, Jing Guo, Ke Wang, Clive Randall

Keywords(s):

Category(s): Advanced Materials & Chemicals, MXenes

Enhanced VR Battery Life through Perception-Guided Color Encoding

Innovative VR display power reduction using color perception technology, which enhances battery life without sacrificing visual quality Institute Reference: 1-24019 Background The rapid advancement of Virtual Reality (VR) and Augmented Reality (AR) technologies has resulted in a growing demand for higher resolution, faster refresh rates, and improved...

Published: 10/22/2024 | Inventor(s): Yuhao Zhu, Abhishek Tyagi, Jiayi He, Budmonde Duinkharjav, Kenneth Chen, Qi Sun, Nisarg Ujjainkar

Keywords(s):

Category(s): Optics, Computer Software, Devices

Exploiting Human Color Discrimination for Memory- and Energy-Efficient Image Encoding in Virtual Reality

A VR image compression algorithm reducing DRAM traffic by 66.9% with minimal perceptual quality loss Institute Reference: 1-24027 Background Virtual Reality (VR) is emerging as a ubiquitous computing platform, with applications spanning healthcare, education, communication, training, and design. Efficient computing substrates are critical to VR’s...

Published: 10/22/2024 | Inventor(s): Yuhao Zhu, Nisarg Ujjainkar, Ethan Shahan, Kenneth Chen, Qi Sun, Budmonde Duinkharjav

Keywords(s):

Category(s): Optics, Computer Software, Devices

Modified CRISPR-Cas9 system for enhanced gene editing

This invention enhances the CRISPR-Cas9 gene-editing system by modifying the Cas9 protein’s Rec3 clamp region, improving its fidelity, specificity, and speed, reducing off-target effects, and increasing precision for therapeutic and research applications. Background Genome engineering is a rapidly advancing field that involves the precise modification...

Published: 10/21/2024 | Inventor(s): David Taylor, Kenneth Johnson, Jack Bravo, Tyler Dangerfield

Keywords(s):

Category(s): Life sciences > Research tools > Reagent

Blood pressure regulation via thermal control during sleep

This technology uses a stimulating device and blood pressure monitor to regulate blood flow and lower blood pressure during sleep through targeted thermal stimulation, promoting cardiovascular health by integrating into a climate-controlled bed. Background High blood pressure, or hypertension, is a significant health concern linked to various cardiovascular...

Published: 10/4/2024 | Inventor(s): Kenneth Diller, Sepideh Khoshnevis, Laura Hemmen Namisnak

Keywords(s):

Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Diagnostic

Flexible heat exchange pad for enhanced thermal therapy and skin temperature control

The heat exchange pad is a flexible, 3D-printed device designed to control skin temperature by circulating fluid through microchannels that mimic the vascular network of glabrous skin, enhancing heat transfer efficiency and conforming to patient anatomy. Background Managing body temperature effectively is crucial in various medical scenarios, such...

Published: 10/4/2024 | Inventor(s): Gary McGregor, Kenneth Diller

Keywords(s):

Category(s): Life sciences > Medical technology > Medical devices

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