Search Results - kenneth+o

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Improving the sensitivity and range of detection with ligation of DNA nanoswitches
This technology uses enzymatic ligation in DNA nanoswitches to detect very short or rare DNA and RNA sequences with high sensitivity, amplifying signals by recycling targets so even single molecules can be identified for diagnostics and research. Background: Nucleic acid detection is a cornerstone of modern molecular biology, diagnostics, and biotechnology,...
Published: 3/11/2026   |   Inventor(s): Kenneth Halvorsen, Jibin Punnoose, Vinod Morya
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
A 3D printable mini-gel electrophoresis system and methods for use
This technology is a low-cost, 3D printable mini-gel electrophoresis system with built-in electrodes, enabling rapid, portable DNA analysis using battery power—ideal for education, fieldwork, and labs with limited resources. Background: Gel electrophoresis is a cornerstone technique in molecular biology, widely used for the separation and analysis...
Published: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Andrew Hayden, Vinod Morya
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics
Expanding DNA nanoswitch utility with detection by aptamers
This technology integrates aptamers into DNA nanoswitches, enabling sensitive detection of a wide range of biomolecules—including proteins and small molecules—for use in diagnostics, research, and biosensing applications. Background: Molecular detection technologies are foundational in fields such as diagnostics, biomedical research,...
Published: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
Methods for detecting RNA modifications with DNA nanoswitches
This technology uses DNA nanoswitches to directly and specifically detect RNA modifications, allowing simultaneous identification of multiple modifications in their natural sequence context for research, diagnostics, and drug discovery applications. Background: RNA modifications, such as methylation, play critical roles in gene regulation, cellular...
Published: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Iranna Todkari, Andrew Hayden
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Design and Synthesis
Mechanically Tunable Engineered Heart Tissue Platform
Next-generation engineered heart tissue platform that enables precise tuning of mechanical properties of microenvironment to study the structure, development, and function of cultured cells or human-derived cardiac tissues. Problem: Engineering heart tissue (EHT) platforms have the potential to study heart physiology, disease pathology, and therapeutic...
Published: 1/30/2026   |   Inventor(s): Kenneth Margulies, Benjamin Lee, Nesrine Bouhrira
Keywords(s): Bioengineering, Cardiovascular, Drug Target, Platform Technology
Category(s): Technology Classifications > Hardware & Components, Technology Classifications > Research Tools & Reagents, Technology Classifications > Testing & Measurement
A smartphone-based machine learning system for non-invasive detection and assessment of fetal movements
This technology uses a smartphone app and microphone placed on a pregnant woman’s abdomen to record and analyze fetal movement sounds with AI, providing at-home, non-invasive monitoring and alerts for both patients and clinicians to improve prenatal care. Background Fetal movement monitoring is a critical aspect of prenatal care, as changes...
Published: 1/13/2026   |   Inventor(s): Kenneth Moise, Kelly Gaither
Keywords(s):  
Category(s): Life sciences > Medical technology, Life sciences > Medical technology > TechBio (software innovation in healthcare)
Precision Metathesis Polymerization for Chemically Recycling Plastics
Precisely Inserts In-Chain Functional Groups in Polymer Backbone, Rendering Polyethylene Recyclable This method of precise metathesis polymerization chemically recycles polyethylene by incorporating precisely placed functional groups into the polymer backbone. Plastic waste disposal poses a challenge globally, generating thousands of tons of waste...
Published: 2/4/2026   |   Inventor(s): Kenneth Wagener, Austin Evans
Keywords(s):  
Category(s): Technology Classifications > Engineering > Chemical
Portable Assay for COVID-19 Diagnostic
A low-cost, rapid, and more accurate gel electrophoresis-based assay using DNA nanoswitches for detecting COVID-19 and other viruses. Background: Viral diagnostics are of prime importance for testing infection rates and for timely treatment, especially in the case of a pandemic such as the current COVID-19 outbreak caused by the SARS-CoV-2 corona...
Published: 2/10/2026   |   Inventor(s): Kenneth Halvorsen, Lifeng Zhou
Keywords(s): DNA, RNA, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
Ribonuclease-responsive DNA Nanoswitches
A DNA nanoswitch that provides a simple mix-and-read methodology to detect RNases (ribonucleases) in a biological sample. Background: RNases are involved in many biological processes including neurotoxicity, genome replication and maintenance, immune-suppression, and antitumor activity. RNase inhibitors are also potential drug candidates and biomarkers...
Published: 1/30/2026   |   Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): DNA, RNA, RNA-switch
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Technology Classifications > Diagnostics
Compounds that Disaggregate Alzheimer's Disease-Associated Fibrils of Tau Protein (UCLA Case No. 2022-145, 2025-329)
UCLA researchers in the Department of Biological Chemistry, Chemistry and Biochemistry developed a new tau-inhibiting seven residue peptide and conjugated it to magnetic nanoparticles for the treatment of Alzheimer’s disease. These compounds disaggregate pathogenic tau amyloid fibrils at atomic resolution, restore normal neuronal function, and...
Published: 11/19/2025   |   Inventor(s): David Eisenberg, Ke Hou
Keywords(s):  
Category(s): Therapeutics > CNS and Neurology
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