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Search Results - kenneth+o
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Human Skin-on-a-Chip for Modeling Pressure-Induced Injury and Quantitative Immune Responses for Pre-Clinical Safety
This invention is a full-thickness, immune-responsive human skin-on-a-chip platform designed to model pressure-induced injury and quantitatively assess inflammatory toxicity, barrier dysfunction, and immunogenic response. The platform will function as a next-generation New Approach Method (NAM) supporting pre-clinical safety decision-making and reducing...
Published: 5/18/2026
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Updated: 5/18/2026
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Inventor(s):
Carlos Zgheib
,
Kenneth Liechty
,
Melisa Kafali
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation
,
Technology Classifications > Life Sciences
,
Technology Classifications > Medical Devices
,
Technology Classifications > Research Tools > Simulators and Modeling Tools
Gene Therapy for Optic Neuropathy
Problem: Optic neuritis is a condition commonly observed in MS patients that leads to temporary or permanent visual decline following demyelination of the optic nerve and loss of retinal ganglion cells. Current therapies for MS and ON include immunosuppressive agents that mitigate the inflammatory component of disease. Unfortunately, these treatments...
Published: 5/14/2026
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Updated: 5/14/2026
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Inventor(s):
Kenneth Shindler
,
Devin McDougald
,
Junwei Sun
,
Jean Bennett
Keywords(s):
Category(s):
Technology Classifications > Therapeutics
ERG-7 Inhibitors: Targeting the Sterol Biosynthetic Pathway
This invention relates to small molecule anti-fungal compounds, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of fungal diseases in human and veterinary subjects. In particular aspects, the invention provides inhibitors that modulate fungal sterol biosynthesis, including inhibitors of lanosterol synthase...
Published: 5/6/2026
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Updated: 5/6/2026
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Inventor(s):
Rui Xiong
,
Hongmin Li
,
Malla Reddy Gannarapu
,
Divakar Indukuri
,
Anil Tharappel
,
Ke Chen
,
Mengjiao Ma
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Infectious Diseases
,
Technology Classifications > Healthcare Portfolios > Neurology
,
Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
,
Technology Classifications > Life Sciences > Small Molecules
,
Technology Classifications > Life Sciences > Therapeutics
Fast, Background-free Detection of Nucleic Acid Sequences Using DNA Nanoswitches
This technology introduces DNA-based "nanoswitches"—innovative nanostructures that enable precise and efficient detection of target analytes through conformational changes. Background: Accurate detection of specific molecules, such as DNA sequences or other analytes, is fundamental in medical diagnostics, environmental monitoring,...
Published: 5/6/2026
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Updated: 5/5/2026
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Inventor(s):
Kenneth Halvorsen
,
Wesley Wong
,
Arun Richard Chandrasekaran
Keywords(s):
Category(s):
Campus > University at Albany
,
Technology Classifications > Biomedical Science and Engineering
nsP2 Inhibitors: Targeting the Alphavirus nsP2 Protease
This invention relates to antiviral compounds targeting the alphavirus nsP2 protease, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of the Chikungunya virus. This compound selectively interferes with the essential proteolytic processing activity of nsP2, a critical step in the viral life cycle. By blocking...
Published: 4/29/2026
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Updated: 4/29/2026
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Inventor(s):
Hongmin Li
,
Rui Xiong
,
Subodh Samrat
,
Malla Reddy Gannarapu
,
Ran Zhang
,
Ke Chen
,
Mengjiao Ma
,
Omar Alejandro Lozano Ramos
,
Divakar Indukuri
,
Renu Bhardwaj
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Infectious Diseases
,
Technology Classifications > Life Sciences > Therapeutics
,
Technology Classifications > Life Sciences > Small Molecules
DNA Methylation-Based Cancer Diagnostics for Accurate Tumor Classification
Summary: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a collection of T-cell receptors (TCRs) that specifically target the mutated KRAS antigen. This technology encompasses a DNA methylation–based diagnostic platform designed to improve the accuracy and consistency of cancer classification,...
Published: 4/23/2026
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Updated: 4/10/2026
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Inventor(s):
Kenneth Aldape
,
Ziedulla Abdullaev
,
Rustamzhon Turakulov
,
Stefania Pittaluga
,
Mark Raffeld
,
Elaine Jaffe
,
Omkar Singh
,
Antonios Papanicolau-Sengos
Keywords(s):
Category(s):
Application > Diagnostics
,
TherapeuticArea > Oncology
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
Nano-Fern Structured Silver-Copper Electrodes for Electrochemical Reductive Technologies
Invention Description Over the last century, human activity has profoundly disrupted the natural nitrogen cycle, driven largely by the widespread use of ammonia (NH3) produced via the Haber–Bosch (HB) process. While this method is crucial for sustaining the global population, it is highly energy-intensive, requiring extreme temperatures and pressures,...
Published: 3/31/2026
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Updated: 3/31/2026
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Inventor(s):
Sergio Garcia-Segura
,
Kenneth Flores
Keywords(s):
Category(s):
Advanced Materials/Nanotechnology
,
Environmental Remediation/Wastewater Treatment
,
Environmental
,
Physical Science
Improving the sensitivity and range of detection with ligation of DNA nanoswitches
This technology uses enzymatic ligation in DNA nanoswitches to detect very short or rare DNA and RNA sequences with high sensitivity, amplifying signals by recycling targets so even single molecules can be identified for diagnostics and research. Background: Nucleic acid detection is a cornerstone of modern molecular biology, diagnostics, and biotechnology,...
Published: 6/9/2026
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Updated: 3/11/2026
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Inventor(s):
Kenneth Halvorsen
,
Jibin Punnoose
,
Vinod Morya
Keywords(s):
DNA nanoswitches
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Diagnostics
,
Technology Classifications > Biomedical Science and Engineering
A 3D printable mini-gel electrophoresis system and methods for use
This technology is a low-cost, 3D printable mini-gel electrophoresis system with built-in electrodes, enabling rapid, portable DNA analysis using battery power—ideal for education, fieldwork, and labs with limited resources. Background: Gel electrophoresis is a cornerstone technique in molecular biology, widely used for the separation and analysis...
Published: 6/9/2026
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Updated: 3/9/2026
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Inventor(s):
Kenneth Halvorsen
,
Andrew Hayden
,
Vinod Morya
Keywords(s):
3D printing
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Diagnostics
Expanding DNA nanoswitch utility with detection by aptamers
This technology integrates aptamers into DNA nanoswitches, enabling sensitive detection of a wide range of biomolecules—including proteins and small molecules—for use in diagnostics, research, and biosensing applications. Background: Molecular detection technologies are foundational in fields such as diagnostics, biomedical research,...
Published: 6/9/2026
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Updated: 3/9/2026
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Inventor(s):
Kenneth Halvorsen
,
Arun Richard Chandrasekaran
Keywords(s):
aptamers
,
DNA nanoswitches
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Diagnostics
,
Technology Classifications > Biomedical Science and Engineering
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