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Search Results - kenneth+o
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Integrated nano-cavity plasmon laser light-sources
Modern integrated circuits often need on-chip light sources for optical interconnects, but traditional off-chip lasers suffer from drawbacks such as large footprint, high energy consumption, slower modulation speeds, and inefficient coupling losses to on-chip waveguides. Existing approaches rely on III-V semiconductor lasers that are either separately...
Published: 7/28/2025
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Inventor(s):
Volker Sorger
,
Ke Liu
,
Devendra Sadana
Keywords(s):
Category(s):
Technology Classifications > Computers Electronics & Software > Processing Chips
,
Technology Classifications > Computers Electronics & Software > Computing Architecture
Water Immersion Multi-Slit Portable In Vivo Confocal Ophthalmoscope
This technology is a low-cost, portable, scan-less in vivo confocal ophthalmoscope (PICO) that uses a water-immersion objective lens in combination with a multi-slit illumination and detection system. It enables high-resolution, non-invasive imaging of the anterior segment and external structures of the eye at the cellular and subcellular level. The...
Published: 7/22/2025
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Inventor(s):
Dongkyun Kang
,
Kenneth Marcelino
,
Momoka Sugimura
,
Jaya Chidambaram
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Displays
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Technology Classifications > Imaging & Optics > Lens & System Design
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Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
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Technology Classifications > Imaging & Optics > Sensors and Detection
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Technology Classifications > Imaging & Optics > Ophthalmology
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Technology Classifications > Healthcare Portfolios > Ophthalmology
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Technology Classifications > Medical Devices > Diagnostic
P2Y14 Receptor Antagonists for the Treatment of Inflammatory Diseases, Including Pulmonary and Renal Conditions and Chronic Pain
This technology includes the development of selective P2Y14R antagonists for the treatment of asthma, sterile inflammation of the kidney, diabetes, and neurodegeneration. The P2Y14 receptor (P2Y14R) is a target for the treatment of inflammatory diseases, including pulmonary and renal conditions. Selective P2Y14R antagonists have demonstrated efficacy...
Published: 6/11/2025
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Inventor(s):
Young-Hwan Jung
,
Zhiwei Wen
,
Kenneth Jacobson
Keywords(s):
Category(s):
Application > Therapeutics
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Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Endocrinology
,
TherapeuticArea > Metabolic Disease
,
TherapeuticArea > Neurology
,
TherapeuticArea > Pulmonology
,
TherapeuticArea > Respiratory
Novel Antibiotic Inhibiting Elongation Factor Complex in Gram-Positive Bacteria
Invention Summary: Antibiotic resistance remains a global health challenge with millions of related deaths each year. Gram-positive bacterial infections, like those caused by Staphylococcus aureus, are likely to acquire and develop resistance to clinically available antibiotics. Therefore, it is crucial to identify and develop novel antibiotics...
Published: 6/5/2025
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Inventor(s):
Wlodek Mandecki
,
Emanuel Goldman
,
Maxim Chudaev
,
Mark Henderson
,
Juan Marugan
,
Wenjuan Ye
,
Kenneth Wilson
,
Dane Parker
Keywords(s):
Antibacterial
,
Small molecules
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Infectious Disease
,
Technology Classifications > Therapeutics
Predictive Neural Network Screening for Post-Operative Urinary Retention
Uses a Dual-Model Machine Learning Model to Predict Urinary Retention Following Spinal Surgery This stacked machine learning algorithm accurately predicts post-operative urinary retention (POUR) following lumbar spine surgery by analyzing patient medical history and surgical details. In the United States, more than 1.62 million spine surgeries occur...
Published: 7/14/2025
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Inventor(s):
Ken Porche
Keywords(s):
Category(s):
Technology Classifications > Software > Healthcare IT
First in class Small Molecule Agonists of the mammalian Relaxin family receptor 1 (RXFP1) and use in treatment of cancer, fibrotic, and vascular disorders (HHS Ref No. E-145-2024-0-US-02)
It is well documented in literature that activation of RXFP1 by relaxin induces: 1) up-regulation of the endothelin system which leads to vasodilation; 2) extracellular matrix remodeling through regulation of collagen deposition, cell invasiveness, proliferation, and overall tissue homeostasis; 3) a moderation of inflammation by reducing levels of inflammatory...
Published: 5/30/2025
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Inventor(s):
Juan Marugan
,
Mark Henderson
,
Kenneth Wilson
,
Wenwei Huang
,
Wenjuan Ye
,
Noel Southall
,
Jiankang Jiang
,
Khalida Shamim
,
Bing Li
,
Alexander Agoulnik
,
Abhijeet Kapoor
,
Joshua Hutcheson
,
Ana Cabrera
,
Irina Agoulnik
Keywords(s):
Category(s):
Application > Therapeutics
,
Application > Research Materials
,
TherapeuticArea > Oncology
,
TherapeuticArea > Cardiology
,
TherapeuticArea > Pulmonology
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TherapeuticArea > Dermatology
,
TherapeuticArea > Reproductive Health
,
TherapeuticArea > Geriatrics
Visualization of Individual Coagulation Profiles
Undetected variations in an individual’s global hemostasis are risk factors for cardiovascular and neurovascular disease both in therapeutic treatment and in “normal” situations such as pregnancy and aging. Professor Brummel-Ziedins and her team have developed algorithms to support clinical visualization of individual patient hemostatic...
Published: 5/21/2025
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Inventor(s):
Kathleen Brummel-Ziedins
,
Christopher Danforth
,
Kenneth Mann
,
Thomas Orfeo
,
Stephen Everse
Keywords(s):
Category(s):
Technology Classifications > Biomedical
Next-Generation 5-HT-2B Serotonin-Receptor Antagonists for Anti-Fibrotic & Cardiopulmonary Therapy
This technology includes a family of small-molecule antagonists that selectively block the 5-HT2B serotonin receptor—an upstream driver of tissue-remodeling—to address fibrotic, cardiopulmonary and related disorders. Built on a conformationally-locked “(N)-methanocarba” nucleoside scaffold, the compounds show nanomolar potency,...
Published: 5/14/2025
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Inventor(s):
Kenneth Jacobson
,
Dilip Tosh
Keywords(s):
Category(s):
Application > Research Materials
,
Application > Therapeutics
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Cardiology
,
TherapeuticArea > Dermatology
,
TherapeuticArea > Immunology
,
TherapeuticArea > Metabolic Disease
,
TherapeuticArea > Oncology
,
TherapeuticArea > Pulmonology
,
TherapeuticArea > Respiratory
RNA Purification with DNA Nanoswitches
Novel, user-centric technology for detecting and analyzing RNA that accelerates the pace of discovery in RNA research. Background: RNA purification is an important part of biomedical research, and very few tools exist for pulling specific RNAs out of a complex solution. Further, understanding of RNA and its complex roles in biology is constantly evolving....
Published: 5/13/2025
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Inventor(s):
Kenneth Halvorsen
,
Lifeng Zhou
Keywords(s):
Category(s):
Campus > University at Albany
,
Technology Classifications > Diagnostics
,
Technology Classifications > Research Tools and Reagents
Portable Assay for COVID-19 Diagnostic
A low-cost, rapid, and more accurate gel electrophoresis-based assay using DNA nanoswitches for detecting COVID-19 and other viruses. Background: Viral diagnostics are of prime importance for testing infection rates and for timely treatment, especially in the case of a pandemic such as the current COVID-19 outbreak caused by the SARS-CoV-2 corona...
Published: 5/13/2025
|
Inventor(s):
Kenneth Halvorsen
,
Lifeng Zhou
Keywords(s):
DNA
,
RNA
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Diagnostics
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