Search Results - long+bone%2fjoint+repair

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Osteoanabolism by 14-3-3zeta
Project ID: D2021-48 Background Bone loss is one of the common symptoms associated with normal aging and pathologies. An increased bone mass loss and mineral density are the primary reason for osteoporosis, arthritis, fractures, etc. Together it affects millions of individuals in the US alone. While several drugs targeting the prevention of bone...
Published: 6/18/2024   |   Inventor(s): Ritu Chakravarti, Saurabh Chattopadhyay
Keywords(s): 14-3-3z, 14-3-3 zeta, Arthritis, Autoimmune, Osteoarthritis, Rheumatoid Arthritis
Category(s): Inflammation & Immunity, Long Bone/Joint Repair
Thermoresponsive Injectable Microparticles-Gel Composites with Low Dose of Recombinant BMP-9 and VEGF for Bone Repair
Project ID: D2019-30 Background: With an estimated 6.3 million bone related injuries in the US, the cost for treating has skyrocketed. While autograft methods are associated with morbidity and pain along with high resorption rate, allograft methods are prone to a high risk of disease transmission and immunogenic rejection. Thus, there is an increasing...
Published: 5/9/2024   |   Inventor(s): Ambalangodage Champa Jayasuriya, Bipin Gaihre
Keywords(s): Allograft, Autograft, Biomaterials, BMP-9, Bone Regeneration, Bone Repair, Microparticle Gel, Orthopedic, VEGF
Category(s): Long Bone/Joint Repair, Spine, Medical Device
Fixation and Reconstruction System for Ankle Fractures
Project ID: D2018-27Background Syndesmotic Ankle fractures are common, and sometimes challenging to treat clinically. These fractures are a common source of substantial patient morbidity. It is estimated that about 290,000 people suffer syndesmotic ankle injuries every year in the United States. Devices that are currently used to treat these ankle...
Published: 6/18/2024   |   Inventor(s): Jiayong Liu, Josh Vander Maten
Keywords(s): Ankle, Diastasis, Fixation, Fracture, Orthopedic, Reconstruction, Syndesmosis
Category(s): Long Bone/Joint Repair, Medical Device
External Locking Fixation for Tibia Fractures
Project ID: D2018-25Background Extra-articular tibia fractures which include proximal tibia, diaphysis and distal tibia fractures are often associated with many serious complications and result in disability. Current treatment methods include the use of an intramedullary rod, an internal locking/unlocking plate, and an external fixator. However, these...
Published: 6/18/2024   |   Inventor(s): Jiayong Liu, Matthew Mazur, Stephen Snider
Keywords(s): Diaphysis, Extra-articular , Fracture, Orthopedic, Tibia
Category(s): Long Bone/Joint Repair, Medical Device