Search Results - vegf

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Engineered T Cells Capable of Simultaneous Tumor Targeting and Alteration of Tumor Microenvironment Through Vasculature Normalization (UCLA Case No. 2023-264)
UCLA researchers in the Department of Microbiology, Immunology and Molecular Genetics have built a series of chimeric antigen receptor (CAR)-T cells that target different antigens and secrete different anti-angiogenic proteins. Additionally, researchers also constructed bispecific CARs that respond to tumor antigen and pro-angiogenic molecules. BACKGROUND:...
Published: 7/31/2025   |   Updated: 6/27/2024   |   Inventor(s): Yvonne Chen
Keywords(s): Cancer, Cancer Immunotherapy, CAR-T cell therapy, immunosuppression, Immunosuppressive Drug, Immunotherapy, solid tumors, Tumor microenvironment, tumor vasculature, VEGF
Category(s): Therapeutics > Oncology
Thermoresponsive Injectable Microparticles-Gel Composites with Low Dose of Recombinant BMP-9 and VEGF for Bone Repair
Bone repair remains a major clinical need because autograft and allograft approaches can be limited by donor-site morbidity, pain, resorption, disease-transmission risk, and immune rejection. Tissue-engineered alternatives seek to combine osteoconductive scaffolds, osteoinductive factors, and regenerative cells, but many scaffold systems require invasive...
Published: 5/13/2026   |   Updated: 8/19/2019   |   Inventor(s): Ambalangodage Jayasuriya, Bipin Gaihre
Keywords(s): Allograft, Autograft, Biomaterials, BMP-9, Bone Regeneration, Bone Repair, Microparticle Gel, Orthopedic, VEGF
Category(s): Long Bone/Joint Repair, Spine, Medical Device