Search Results - life+science+(all+ls+techs)

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Computational Method to Identify Protein Hotspots and Allosteric Sites
Invention Description Protein allostery is important in many biological processes and drug development. Understanding the mechanisms involved would be highly beneficial for therapeutic interventions. Existing techniques focus primarily on equilibrium dynamics and network analysis for allosteric interaction mapping. Unfortunately, these are limited...
Published: 1/12/2026   |   Inventor(s): Paul Campitelli, Tushar Modi, Sefika Banu Ozkan
Keywords(s):  
Category(s): Vaccines/Antimicrobials, Proteomic Assays/Reagents/Tools, Life Science (All LS Techs), Computing & Information Technology, Artificial Intelligence/Machine Learning
Computational Method to Identify Mutational Epistasis in Proteins
Invention Description Viral evolution, particularly rapid viral evolution, can lead to the emergence of variants of concern. In order to develop effective antiviral strategies, it is essential to understand the molecular mechanisms driving these adaptations. Some research has focused on identifying adaptive mutations and how they impact protein structure...
Published: 1/12/2026   |   Inventor(s): Paul Campitelli, Nicholas Ose, Tushar Modi, Ismail Can Kazan, Sefika Banu Ozkan
Keywords(s):  
Category(s): Vaccines/Antimicrobials, Life Science (All LS Techs), Computing & Information Technology, Artificial Intelligence/Machine Learning, COVID-19, SARS-CoV-2, Coronavirus
User-Actuated Valve Actuator for Microfluidic Devices
Invention Description Lab-on-a-chip technology and microfluidic diagnostic devices often rely on complex mechanical or electrical systems to manipulate fluid, making them costly and bulky. These components may limit portability, decrease operational lifetime, and prevent widespread use by untrained personnel or patients at the point of care or at home....
Published: 1/12/2026   |   Inventor(s): Clifford Anderson, Vi Nguyen, Jennifer Blain Christen
Keywords(s): Analytical Devices, Bioassay, Biosensor, Fluid, Micro-Fluidics
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Point of Care
Integrated Microfluid Cartridge for POC Biofluid Diagnostics
Invention Description Rapid and reliable nucleic acid assays are critical for diagnosing infectious diseases at the point of need, yet most systems rely on complex, expensive instrumentation and trained personnel. These requirements limit access to timely diagnostics in low-resource, remote, or decentralized settings. Many platforms typically require...
Published: 1/6/2026   |   Inventor(s): Vi Nguyen, Clifford Anderson, Jennifer Blain Christen
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Coronavirus, COVID-19, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care, SARS-CoV-2
DNA Nanotechnology Platform for 3D Nanoscale Manufacturing
Invention Description One of the main challenges in nanoscale manufacturing is achieving precise three-dimensional (3D) positioning and organization of materials. DNA nanotechnology, such as DNA origami, offers a solution to this problem by leveraging the predictable base-pairing properties of DNA to design and construct nanoscale structures with molecular...
Published: 1/5/2026   |   Inventor(s): Petr Sulc, Hao Liu, Thong Diep, Matthew Sample, Michael Matthies, Joshua Evans
Keywords(s):  
Category(s): Life Science (All LS Techs), Nucleic Acid/Peptide/Protein Therapies, Vectors/Constructs/Plasmids, Biological Nanotechnology
Fluorescently Labeled INtracellular Genomics (FLING) and Fluorescent In Situ Amplified (FISA)
Invention Description Accurately identifying and sequencing rare genotypes within complex cell populations remains a major challenge across biological research. Conventional sequencing approaches often require large amounts of high-quality DNA, struggle with heterogeneous or degraded samples, and fail to retain the spatial or cellular context necessary...
Published: 12/11/2025   |   Inventor(s): Kerry Geiler-Samerotte, Leandra Brettner, Parker Crossland, Kara Schmidlin
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Imaging
GLIMMER: Advanced Blood Glucose Prediction Model for Type 1 Diabetes
Invention Description Type 1 diabetes (T1D) is an autoimmune disease where the body attacks and destroys insulin-producing beta cells in the pancreas and affects nearly 10 million people globally. Because glucose needs to be continuously monitored for precise insulin dosing, managing T1D is challenging. While automated insulin delivery (AID) systems...
Published: 11/18/2025   |   Inventor(s): Hassan Zadeh, Saman Khamesian
Keywords(s):  
Category(s): Artificial Intelligence/Machine Learning, Computing & Information Technology, Life Science (All LS Techs), Medical Devices, Educational
Multiomic Approaches to Pediatric Inflammatory Bowel Disease
Invention Description Pediatric Inflammatory Bowel Disease (IBD), encompassing Crohn’s Disease and Ulcerative Colitis, presents significant clinical challenges due to its complex and heterogeneous nature, often leading to lifelong health complications. Current diagnostic and therapeutic strategies are limited by an incomplete understanding of...
Published: 1/17/2026   |   Inventor(s): Todd Sandrin, Peter Jurutka, Haiwei Gu, Brad Pasternak
Keywords(s):  
Category(s): Applied Technologies, Diagnostic Assays/Devices, Life Science (All LS Techs), Pharmaceuticals, Proteomic Assays/Reagents/Tools, Artificial Intelligence/Machine Learning
Unified Model of Alzheimer’s Disease Pathobiology
Invention Description Understanding of the pathobiology of Alzheimer’s disease (AD) has long been fragmented, with much research centered around biological mechanisms including amyloid β or tau proteins, inflammation, cell death pathways, glia, mitochondria and more. While these all deal with real facets in the biology of AD, they are limited...
Published: 1/6/2026   |   Inventor(s): Carol Huseby, Elaine Delvaux, Paul Coleman
Keywords(s):  
Category(s): Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Neurodegenerative Disease Technologies, Pharmaceuticals
Brassiere for the Treatment of Mastalgia and Breast Asymmetry
Invention Description Breast pain (mastalgia) can be attributed to many things, including hormones, diseases, breast asymmetry and improper breast support. Mastalgia is very common, affecting up to 70% of women across the globe at some point in their lives. Current remedies, including anti-inflammatories and hormonal treatments address symptoms but...
Published: 11/24/2025   |   Inventor(s): Rajpal Tiger, Vikram Kodibagkar, Grant Lindstrom, Brode Fendley, Nicholas Jimenez, William Hack, Cullanete Bloom
Keywords(s):  
Category(s): Life Science (All LS Techs), Medical Devices
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