Search Results - life+science+(all+ls+techs)

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SDS-PAGE is a ubiquitous analytical technique for separating proteins based on molecular weight. Existing loading buffers used in SDS-PAGE and other protein analyses techniques have difficulty in effectively solubilizing and stabilizing hydrophobic or lipidated proteins, particularly membrane proteins. These proteins tend to aggregate or precipitate...

Published: 6/28/2025 | Inventor(s): Debra Hansen, Petra Fromme, Jeyatharshika Antonyrajah

Keywords(s):

Category(s): Imaging, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools

Photoacoustic Nanosensor Probes for Imaging Neurotransmitter Dynamics

The ability to monitor spatiotemporal dynamics of neurotransmitter release is crucial for understanding the basis of brain function. The precise cognitive operations supported by the changes in cortical neuromodulatory activity have not been fully recognized, largely due to the limitations of current methods which have trade-offs between spatial, temporal,...

Published: 6/28/2025 | Inventor(s): Heather Clark

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Biological Nanotechnology, Life Science (All LS Techs), Imaging, Medical Devices, Medical Imaging

Plasmonic Cell Force Microscopy

Cellular force is important in activities including migration, proliferation and differentiation, which are mediated by interactions between the cell and the ECM. Monitoring these interactions helps to understand how and when mechanical cues play a role in cellular events and underlying mechanisms. However, there are limitations in spatial and temporal...

Published: 6/24/2025 | Inventor(s): Shaopeng Wang, Xinyu Zhou, Ryan Porter

Keywords(s):

Category(s): Imaging, Life Science (All LS Techs), Medical Imaging

Nucleic Acid-Triggered Gated Pore Formation for Sensing and Signal Amplification

Cells have developed various means for transporting molecules across membranes as well as cellular compartments separated by membranes. Channels and pores can be formed with different protein assemblies to enable the regulated passage of molecules in and out of cells, which has led to them being exploited as molecular sensors for characterizing biomolecules...

Published: 6/23/2025 | Inventor(s): Rizal Hariadi, Ranjan Sasmal

Keywords(s):

Category(s): Biological Nanotechnology, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices

Skin-on-a-Chip Microfluidic Device

Dermatology and beauty product research and development and testing has been limited to animal testing, which in some countries has been banned. Because of increasing controversial issues surrounding animal testing of these dermatology or beauty products, there has been increasing interest in developing in-vivo like in-vitro models for skin research. ...

Published: 6/11/2025 | Inventor(s): Mehdi Nikkhah, Shaun Wootten, Ronin-Mae Komarnisky

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Life Science (All LS Techs), Biomaterials, Medical Devices

Pneumatically Controlled RF Coils for MRI & Spectroscopy

Radio Frequency (RF) coils transmit and receive RF signals in magnetic resonance imaging (MRI). Designing FR coils is a challenge because they often have to operate at multiple frequencies and it is difficult to enable them to resonate at multiple frequencies or switch their resonating frequencies. Positive-intrinsic-negative (PIN) diodes are commonly...

Published: 6/10/2025 | Inventor(s): Sung-Min Sohn, Chavalchart Herabut

Keywords(s):

Category(s): Imaging, Life Science (All LS Techs), Medical Devices, Medical Imaging

One-Step Label-Free Molecular Interaction Kinetic Measurement

Molecular interactions are integral to virtually all biological processes including cell signaling, enzyme activity, protein functionality, and disease development. Understanding the kinetics of these interactions is crucial for providing detailed quantitative and mechanistic insights, at the molecular level, which are essential for advancements in...

Published: 6/10/2025 | Inventor(s): Shaopeng Wang, Xiaoyan Zhou

Keywords(s):

Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Imaging, Life Science (All LS Techs)

Dynamic-based Computational Drug Design Strategy for WW Domains

Understanding the relationship between protein sequence-structure and binding dynamics is not well understood. Of particular interest is the ability to relate foldability and function of a protein and the ability to characterize how foldability and binding change based on mutations in the protein sequence. WW domains are one of the most abundant independently...

Published: 6/3/2025 | Inventor(s): Jin Lu, Ismail Can Kazan, Sefika Banu Ozkan

Keywords(s):

Category(s): Artificial Intelligence/Machine Learning, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools

DGR-MIL: Diverse Global Representation in Multiple Instance Learning

Histological whole slide image (WSI) processing techniques are critical for identifying and classifying tissues, particularly cancerous tissues. AI-aided methods for analyzing these WSIs have become increasingly important to enhance diagnostic precision and high throughput processing. However, WSIs have gigapixel resolution, leading to computational...

Published: 5/28/2025 | Inventor(s): Wenhui Zhu, Xiwen Chen, Peijie Qiu, Yalin Wang, Aristeidis Sotiras, Abolfazl Razi

Keywords(s):

Category(s): Artificial Intelligence/Machine Learning, Computing & Information Technology, Imaging, Life Science (All LS Techs)

Microbial Air Quality Monitoring System (MAQMS)

Air quality monitoring is critical for environmental health and public safety. Traditional monitoring methods rely on passive and active air sampling techniques, which, while effective, are cumbersome, expensive and limited with respect to real-time data and comprehensive analyses. In high-risk environments, such as hospital or care settings, and food...

Published: 5/19/2025 | Inventor(s): Amir Elyaderani

Keywords(s): CO2 sensor, Early Detection, Environmental, Informatics, PS-Bioengineering, Medical, Sensors, PS-Environmental, Public Health Technology, Real-Time System, Viral, Virus

Category(s): Artificial Intelligence/Machine Learning, COVID-19, Life Science (All LS Techs), Intelligence & Security, Environmental

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