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Search Results - life+science+(all+ls+techs)
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Method for Repurposing FDA-approved Therapeutics & Composition for Treating Mesothelioma
The amount of time and money that goes into getting a drug from initial discovery to FDA approval is substantial, typically involving at least 10 years and hundreds of millions of dollars. Because of this, there has been a growing interest in repurposing drugs which have previously been approved for human use, particularly since their MOA as well as...
Published: 1/7/2025
|
Inventor(s):
Chris Plaisier
,
Sierra Wilferd
,
Choung Hoang
Keywords(s):
Cancer
,
Drug
,
Drug Discovery
Category(s):
Pharmaceuticals
,
Cancer
,
Cancer Therapeutics
,
Artificial Intelligence/Machine Learning
,
Computing & Information Technology
,
Life Science (All LS Techs)
Precision Medicine for Psychedelic Therapies
Stress related psychiatric disorders (SRPDs) such as post-traumatic stress disorder (PTSD), major depressive disorder (MDD), mood disorders, psychotic disorders, anxiety disorders, substance use disorders (SUDs) and more, are a leading disease burden worldwide with increasing diagnoses among adolescents as well as adults. They are influenced by both...
Published: 12/11/2024
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Inventor(s):
Candace Lewis
Keywords(s):
Category(s):
Life Science (All LS Techs)
,
Non-Cancer Therapeutics
,
Pharmaceuticals
,
Computing & Information Technology
,
Artificial Intelligence/Machine Learning
Biofeedback Device for Speech Modulation
Neurodegenerative diseases, such as Parkinson’s Disease (PD), affect many of the body’s functions such as balance and movement. They can also have a profound effect on communication abilities, with the majority of patients suffering from some form of vocal impairment, usually a difficulty in modulating vocal intensity. These speech difficulties...
Published: 12/12/2024
|
Inventor(s):
Nithish Kumar Saravanan
,
Kirthik Roshan Nagaraj
,
Ezhilan Veluchami
,
Ramprakash Sridharan
,
Tyler Hulson
,
Zane Reynolds
,
Tara Chay
,
Maura Rhodes
Keywords(s):
Category(s):
Life Science (All LS Techs)
,
Manufacturing/Construction/Mechanical
,
Medical Devices
,
Neurodegenerative Disease Technologies
,
Artificial Intelligence/Machine Learning
Novel Human C3 Derivatives for Therapeutic Complement Depletion
The complement system is part of the immune system and is important in both innate and adaptive immunity. However, the complement system can also be a pathogenetic factor in many diseases including, rheumatoid arthritis, reperfusion injury, myasthenia gravis, and more. Complement has also been shown to be important for the development of antibodies...
Published: 11/11/2024
|
Inventor(s):
Carl-Wilhelm Vogel
,
Paul Finnegan
,
Julie Rayes
,
Sebastien Lacroix-Desmazes
Keywords(s):
Category(s):
Cancer Therapeutics
,
Life Science (All LS Techs)
,
Non-Cancer Therapeutics
,
Pharmaceuticals
Formulations to Prevent Neurological Diseases and Disorders, including TBI
Traumatic brain injury (TBI) is a major source of death and long-term physical, cognitive and mental disability worldwide, with roughly 27 million new cases each year. In the U.S. alone, this results in almost 70,000 deaths, annually. Although TBIs can affect people of all ages, the risk of getting a TBI is greatest in adolescents, young adults and...
Published: 11/4/2024
|
Inventor(s):
Abhinav Acharya
,
Sarah Stabenfeldt
Keywords(s):
Category(s):
Vaccines/Antimicrobials
,
Pharmaceuticals
,
Non-Cancer Therapeutics
,
Neurodegenerative Disease Technologies
,
Life Science (All LS Techs)
Ultrasonic System for Material Characterization & Flaw Detection
The utilization of ultrasound imaging is common for material characterization and detection of flaws in small-scale biological tissues and soft materials because it provides quantitative and relevant information. However, this imaging modality relies on the probe coming into direct contact with the soft material in order to minimize excess attenuation...
Published: 10/18/2024
|
Inventor(s):
Erik Maas
,
Leila Jannesari Ladani
Keywords(s):
Category(s):
Imaging
,
Life Science (All LS Techs)
,
Manufacturing/Construction/Mechanical
,
Medical Devices
,
Medical Imaging
Facilitating Growth of Photosynthetic Microbes with CO2 Nanobubbles
Photosynthetic microbes are promising contributors to the bioeconomy. With light and CO2, they can create biomass, biofuels, green chemicals, food ingredients and more. Typically, CO2 is delivered by sparging; however, CO2 macrobubbles quickly rise to the surface and are lost to the atmosphere. This gas transfer inefficiency not only increases operational...
Published: 10/9/2024
|
Inventor(s):
Aldis Darzins
,
Willem Vermaas
,
Shuqin Li
Keywords(s):
Category(s):
Advanced Materials/Nanotechnology
,
Alternative Energy/Biofuels/Bioplastics/Algae
,
Life Science (All LS Techs)
,
Photosynthetic Organisms & Culture Systems
RNA Sensor Platform for Targeting Cancer Fusion Genes and Transcripts
Many cancers have recurrent chromosomal translocations leading to the fusion of two genes. Often, said cancers are aggressive, have a poor prognosis with metastasis or recurrence, and do not have effective and targeted treatment. The challenge of many fusion-positive cancers is the lack of established targets downstream of the gene fusion despite years...
Published: 10/8/2024
|
Inventor(s):
Albert Cheng
,
Ching Lau
,
Nathaniel Jilette
,
Jacqueline Jufen Zhu
Keywords(s):
Category(s):
Cancer
,
Cancer Therapeutics
,
Chemical/Biological Sensors
,
Genomic Assays/Reagents/Tools
,
Life Science (All LS Techs)
Stimulation Device to treat Hand Weakness from Stroke or Spinal Injury
A growing number of people experience hand weakness due to stroke or spinal cord injuries. Electrical stimulation (e-stim) devices are commonly used to assist in hand weakness therapy. However, they are bulky, expensive, uncomfortable (may be ill-fitting, cause skin irritation or unpleasant sensation), and non-portable, eliminating the potential for...
Published: 9/24/2024
|
Inventor(s):
Atharva Wani
,
Niteesh Nigam
,
Onkar Chavan
,
Yash Bellap
,
Joelly Lobato
,
Ishan Swanand Vyas
,
Suhrud Parag Joglekar
Keywords(s):
Category(s):
Life Science (All LS Techs)
,
Medical Devices
,
Manufacturing/Construction/Mechanical
Vital Signs Monitoring using Depth Cameras
Cardiovascular disease is responsible for an estimated 17.9 million deaths each year, making it the leading cause of death worldwide. Continuous heart health monitoring way is the best preventative for heart failure. However, standard monitoring devices, including ECG and PPG, require direct physical contact, which can be difficult for certain patient...
Published: 10/22/2024
|
Inventor(s):
Yu Rong
,
Daniel Bliss
Keywords(s):
Category(s):
Computing & Information Technology
,
Medical Devices
,
Life Science (All LS Techs)
,
Medical Diagnostics/Sensors
,
Medical Imaging
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