Search Results - k.+christopher+garcia

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Orthogonal Cytokine Enhanced CAR T Cells Generated Through Gene Editing
Brief Description: The present disclosure provides methods of producing a modified immune cell responsive to orthogonal cytokine signaling and a modified immune cell produced by said method. The present disclosure further provides a modified immune cell responsive to orthogonal cytokine signaling and methods for treating cancer comprising the modified...
Published: 8/21/2025   |   Inventor(s): K. Christopher Garcia, Michael Milone, Qian Zhang
Keywords(s): Cell Therapy, Immunology, Immunoncology, Immunotherapy, Oncology, Platform Technology
Category(s): Technology Classifications > Therapeutics
HIGH-THROUGHPUT FORCE-DEPENDENT CELLULAR RESPONSE ASSAY USING SPECTRALLY ENCODED SMART BEADS
­HIGH-THROUGHPUT FORCE-DEPENDENT CELLULAR RESPONSE ASSAY USING SPECTRALLY ENCODED SMART BEADS Researchers at Stanford have developed a technology that uses biomechanical force to initiate T-cell triggering in a high throughput method, facilitating the exploration of the force- and sequence-dependent landscape of T-cell responses. Adaptive immunity...
Published: 3/17/2023   |   Inventor(s): Xiang Zhao, Adam White, Polly Fordyce, Yinnian Feng, K Garcia
Keywords(s): Catch Bond, High-Throughput Mechanobiology, Ligand Discrimination, Mechanotransduction, Single-Cell Microfluidics, Spectrally Encoded Beads, T-Cell Activation, T-Cell Biophysics, T-Cell Receptor
Category(s): Technology Classifications > Biology