Search Results - jonathan+dordick

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Enhanced Stability of Proteins Immobilized on Carbon Nanotubes
RPI ID: 2005-030-201 Innovation Summary: This invention leverages the curvature of nanoparticles, such as carbon nanotubes, to enhance the stability and activity of proteins immobilized on their surfaces. Proteins bound to nanoscale curved surfaces retain biological activity even under harsh conditions, such as high temperature, organic...
Published: 3/10/2026   |   Inventor(s): Prashanth Asuri, Jonathan Dordick, Ravindra Kane, Sandeep Karajanagi, Alexey Vertegel, Richard Siegel
Keywords(s):  
Category(s): Biotechnology and the Life Sciences
Heparin and Heparin Analogs with Exceptional Binding Affinity to SARS-CoV-2 Spike Protein as Potential Therapeutics
RPI ID: 2020-082-401 / 2020-082-601 / 2020-082-602 Innovation Summary: Compositions containing sulfated polysaccharides such as pentosan polysulfate and mucopolysaccharide polysulfate are designed to inhibit SARS-CoV-2 by blocking viral entry and replication. These formulations are intended for mucosal delivery via nasal spray or aerosol, enabling...
Published: 3/10/2026   |   Inventor(s): So Young Kim, Weihua Jin, Jonathan Dordick, Fuming Zhang, Seok-Joon Kwon, Paul Kwon, Keith Fraser, Robert Linhardt
Keywords(s): Heparin, Non-Anticoagulant Heparin, SARS-CoV-2 Spike Protein, TriS HS
Category(s): Biotechnology and the Life Sciences
ImmunoMag-CRISPR lateral flow assay
RPI ID: 2024-015-301 Innovation Summary: This technology introduces a point-of-care diagnostic system for urinary biomarkers using ultrasensitive ImmunoMag-CRISPR lateral flow assays. It combines magnetic bead-based sample preparation with CRISPR-based detection for enhanced sensitivity and specificity. The system is portable and designed for rapid,...
Published: 3/10/2026   |   Inventor(s): Inseon Lee, Peter Heeger, Jonathan Dordick, Seok-Joon Kwon
Keywords(s): Cas12a, CRISPR, Immunoassay, Kidney transplant rejection, lateral flow assay, Urinary biomarkers
Category(s): Biotechnology and the Life Sciences
MPS and PPS and other sulfated GAG analogs to treat/prevent Monkeypox
RPI ID: 2023-007-601 Innovation Summary: This technology describes therapeutic systems and methods using sulfated glycosaminoglycans (GAGs) and GAG analogs to treat or prevent monkeypox virus (Mpox) infections. The compounds interfere with viral attachment and entry mechanisms, reducing infectivity. The approach is designed for topical or systemic...
Published: 3/10/2026   |   Inventor(s): Robert Linhardt, Jonathan Dordick, Deling Shi, Fuming Zhang
Keywords(s): A29, Chondroitin sulfate, Dermatan sulfate, Heparin, Monkeypox virus
Category(s): Biotechnology and the Life Sciences