Search Results - jinghe+huang

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Controlled Tunnel Gap Device for Sequencing Polymers

To reduce costs and increase the availability of personalized genomics new approaches to DNA sequencing are required. Nanopore sequencing is one proposed technique. In nanopore sequencing, DNA molecules are forced through a tiny aperture by electrophoresis. As the individual bases transit the nanopore, their identity can be determined, in theory, by...

Published: 10/17/2024 | Inventor(s): Stuart Lindsay, Shuai Chang, Jin He, Peiming Zhang, Shuo Huang

Keywords(s): Bio-Technology

Category(s): Life Science (All LS Techs)

DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules

The US Government’s pursuit of the “Thousand Dollar Genome” and the “X Prize” goal of even lower cost DNA sequencing are striking examples of the importance being assigned to advances in methods for the DNA sequencing of the human genome. The first technology that finally allows for truly routine genome sequencing will...

Published: 10/17/2024 | Inventor(s): Stuart Lindsay, Colin Nuckolls, Jinyao Tang, Jin He, Peiming Zhang, Kevin Reinhart

Keywords(s):

Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Proteomic Assays/Reagents/Tools

DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules

The US Government's pursuit of the "Thousand Dollar Genome" and the "X Prize" goal of even lower cost DNA sequencing are striking examples of the importance being assigned to advances in methods for the DNA sequencing of the human genome. The first technology that finally allows for truly routine genome sequencing will open a new...

Published: 10/17/2024 | Inventor(s): Stuart Lindsay, Jin He, Peiming Zhang, Kevin Reinhart

Keywords(s):

Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools

N6, A Novel, Broad, Highly Potent HIV-specific Antibody

This is a new antibody coming out of NIAID’s intramural program. N6 has evolved a unique mode of binding that depends less on a variable area of the HIV envelope known as the V5 region and focuses more on conserved regions, which change relatively little among HIV strains. This allows N6 to tolerate changes in the HIV envelope, including the attachment...

Published: 10/28/2024 | Inventor(s): Jinghe Huang, Byong Kang, John Mascola, Elise Ishida, Tongqing Zhou, Anqi Zheng, Peter Kwong, Mark Connors

Keywords(s): ANTIBODY, bNAb, Broad, Highly, HIV-soecific, HIV-Specific, Listed LPM Thalhammer-Reyero as of 4/15/2015, N6, Novel, Ootent, Post LPM Assignment Set 20150420, POTENT, Pre LPM working set 20150418

Category(s): Collaboration Sought > Collaboration

Broadly Neutralizing Human Anti-HIV Monoclonal Antibody 10E8 and Related Antibodies Capable of Neutralizing Most HIV-1 Strains

The uses for human anti-HIV monoclonal antibody 10E8 and its variants include passive immunization, therapeutic vaccination, and the development of vaccine immunogens. 10E8 is one of the most potent HIV-neutralizing antibodies isolated and it neutralizes up to 98% of diverse HIV-1 strains. 10E8 is specific to the membrane-proximal external region (MPER)...

Published: 10/28/2024 | Inventor(s): John Mascola, Leo Laub, Jinghe Huang, Peter Kwong, Gilad Ofek, Jiang Zhu, Gary Nabel, Ivelin Georgiev, Yongping Yang, Rebecca Rudicell, Mark Connors

Keywords(s): antibodies, ANTIBODY, ANTI-HIV, Anti-HIV-1, Anti-HIV-l, Broadly Neutralizing Antibody, DB4AXX, DB4XXX, DBXXXX, DC5AXX, DC5XXX, DCXXXX, DXXXXX, gp41, Human, ISOLATING, Knowledge, mabs, Membrane-Proximal, Method, monoclonal, Neutralizing, prior, Producing, Specificity, VLXXXX, WITHOUT, WJXXXX, XAXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, TherapeuticArea > Immunology, ResearchProducts > Antibodies, Application > Therapeutics, Application > Vaccines

Plush Toys with Arrays of Textile-based Sensors for Interaction Detection

PRODUCT OPPORTUNITIES • Smart plush toys for interaction detection ADVANTAGES • Capable of capturing a range of complex interactions between the plush toy and its end-user • Built-in flexible and light weight non-rigid sensors • Effective and low power-consumption machine learning algorithm...

Published: 11/15/2023 | Inventor(s): Ali Kiaghadi, Jin Huang, Seyedeh Zohreh Homayounfar, Deepak Ganesan, Trisha Andrew

Keywords(s):

Category(s): Physical Science, Software & information technology, Engineering, Devices & sensors

Processing Technique for Ceramic- based Energy Conversion and Storage Devices

Due to rising carbon emissions, extreme weather events and other environmental threats, the demand for alternative energy sources is greater than ever. Therefore, businesses and communities are asking for three things: more affordable electricity, more resilient power, and cleaner energy. Fuel cells, electrolysis cells, membrane reactors, and solid-state...

Published: 10/8/2024 | Inventor(s): Hai Xiao, Jianhua Tong, Fei Peng, Kyle Brinkman, Jincheng Lei, Yuzhe Hong, Hua Huang, Shenglong Mu, Rajendra Bordia

Keywords(s):

Category(s): Manufacturing

Automated Pain Detection in Pediatric Care

uot;Times New Roman",serif; font-size:12pt">Unmet Need: Continuous pain assessment in infants Continuing advances in intensive care have made it possible for premature infants to survive outside the uterus in Neonatal Intensive Care Unit (NICU) even at very early stages of development. Infants in the NICU may receive an estimated 10-14 painful...

Published: 10/8/2024 | Inventor(s): Subhanshu Gupta, Huan Hu, Martin Schiavenato

Keywords(s):

Category(s): Technologies > Health & Well-being > Health-IT, Technologies > Health & Well-being > Medical Devices, Technologies > Energy & Environment > Computer Hardware/Software, Technologies > Energy & Environment > Electrical/Electronics

Layer-by-layer Assembled Nanoparticles for Oral Drug Delivery

Application Layered, casein coated magnetic nanoparticles for oral delivery of drugs protected from acid degradation. Key Benefits Enables oral delivery of hydrophobic drugs that are sensitive to acid degradation in stomach condition. Replaces injections and infusions, reducing side effects and improving patient’s quality of life. Allows...

Published: 11/20/2024 | Inventor(s): Hui Mao, Jing Huang

Keywords(s): Drug Delivery, Imaging

Category(s): TechPub Algolia > Micro and Nanotechnology