Search Results - jianming+wang

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p300 KO HEK293T Cell Line for Multiple Research Applications
This technology includes p300 KO HEK293T cells using crispr/cas9 mediated gene editing technology to be used for various research applications. We showed that p300 deficient cells have impaired glycolysis and are hypersensitive to glucose depletion-induced cell death. p300 is one of major transcriptional co-activators that regulates gene transcription...
Published: 8/12/2024   |   Inventor(s): Ming Ji, Xiaoling Li
Keywords(s):  
Category(s): Application > Research Materials, ResearchProducts > Human Cell Lines, TherapeuticArea > Neurology
Leukemia inhibitory factor- Protective role for radiation/chemo-induced gut syndrome and GVHD
Invention Summary: Currently there is no effective therapy for prevention or treatment of radiation therapy-induced gastrointestinal (GI) tract injury This is also true for Graft-versus-host disease (GVHD) which remains a major complication after allogeneic hematopoietic stem cell transplantation, a widely-used therapy for hematologic malignancies...
Published: 10/4/2022   |   Inventor(s): Wenwei Hu, Zhaohui Feng, Jianming Wang, Huaying Wang
Keywords(s): Anti-cancer, Gastrointestinal disease, Peptides
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Cancer, Technology Classifications > Therapeutics
2020-945 Epitaxy-Enabled Substrate Transfer
SUMMARYUCLA researchers in the Department of Materials Science and Engineering have developed a cost-effective and damage-free method to transfer a selective-area doping structure from one substrate to another via epitaxy.BACKGROUNDDoping is ubiquitous throughout consumer electronics. Doped GaN (Gallium Nitride) is particularly useful owing to the ultra-high...
Published: 7/19/2023   |   Inventor(s): Ya-Hong Xie, Jia Wang, Hiroshi Amano
Keywords(s):  
Category(s): Materials > Functional Materials, Materials > Semiconducting Materials, Materials > Nanotechnology, Electrical > Electronics & Semiconductors, Electrical > Sensors
2017-380 DEVICE AND METHOD FOR MICROSCALE CHEMICAL REACTIONS
Device and Method for Microscale Chemical ReactionsTech ID: 30291 / UC Case 2017-380-0SUMMARYUCLA researchers in the Departments of Bioengineering and Molecular and Medical Pharmacology have developed a passive microfluidic reactor chip with a simplified design that is less costly than existing microfluidic chips.BACKGROUNDAlthough positron emission...
Published: 7/19/2023   |   Inventor(s): R. Michael Van Dam, Jia Wang
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Medical Imaging, PET
Category(s): Diagnostic Markers, Medical Devices > Medical Imaging, Platforms > Diagnostic Platform Technologies, Medical Devices > Medical Imaging > PET
Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...
Published: 3/23/2023   |   Inventor(s): Chung-Jen (James) Chou, Ying Mei, Jia Jia
Keywords(s):  
Category(s): BioPharma
Advanced Engineered Formulations of TMP/Ligustrazine and Microparticle/Nanoparticle Formulations for Inhalation Drug Delivery for Lung Vascular, Interstitial and Airway Diseases
This invention formulates Tetramethylpyrazine (TMP) in a readily deliverable aerosol to treat pulmonary hypertension and other lung diseases. Background: Pulmonary hypertension (PH) is a condition that involves high blood pressure in the arteries of the lungs. Veins stiffen and narrow, making blood flow more difficult and thus, increased pressure...
Published: 11/16/2023   |   Inventor(s): Heidi Mansour, Jason Yuan, Jian Wang, Alexan Gomez, Priyadarshini Muralidharan, Yali Gu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics
Sweat Biomarkers as an Indication of Physiological Conditions
Inventors at the University of Arizona have devised a means by which cortisol isomer ratios in human sweat can be measured and used to evaluate the physiological or psychological state of the patient. Certain cortisol isomer ratios are associated with particular conditions or disorders (high blood pressure, sleep disruption, and others). Other ratios...
Published: 11/16/2023   |   Inventor(s): Esther Sternberg, Min Jia
Keywords(s):  
Category(s): Technology Classifications > Research Tools, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Sensors & Controls > Biologic, Technology Classifications > Medical Devices > Diagnostic
NANOCOMPLEXES FOR DELIVERY OF SAPORIN
Novel protein formulations for cancer therapy using an intracellular delivery formulation.Download a .pdf version of this technology hereIntellectual PropertyUS Publication 2016-0082126
Published: 6/5/2020   |   Inventor(s): Qiaobing Xu, Ming Wang
Keywords(s):  
Category(s): Diseases, Healthcare, Materials
Chemical modification of proteins and peptides for therapy
A series of stimulus-responsive protein modifications to enhance intracellular protein drug delivery.Download a .pdf version of this invention hereIntellectual PropertyUS Publication 2016-0129120
Published: 4/16/2021   |   Inventor(s): Qiaobing Xu, Ming Wang
Keywords(s):  
Category(s): Healthcare, Materials, Nanotechnology, Therapeutic