Search Results - jian+yao

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From Muscle to Mind: Harnessing the Muscle–Brain Axis with Scalable, Muscle-Derived Extracellular Vesicles to Treat Alzheimer’s Disease
Advantages Harnesses the muscle-brain axis, turning human muscle progenitor cells into a renewable source of brain-targeting therapeutic vesicles. Enables scalable, high-yield vesicle production in a compact bioreactor system. Uses a fully xeno-free process for safer, clinically ready, biocompatible manufacturing. Crosses the blood-brain barrier...
Published: 7/15/2026   |   Updated: 7/15/2026   |   Inventor(s): Wanling Xuan, Yao Yao
Keywords(s): Alzheimer's Disease
Category(s): Technology Classifications > Medical > Neuroscience
Novel Laminin Reporter Mouse Line for in vivo Imaging and Laminin Biology Research (Laminin-mCherry/eGFP+/-) Pre-Cre
Advantages First-ever dual-color laminin reporter mouse line. Enables visualization of laminin-γ1 expression in vivo with high fidelity. mCherry signal replicates endogenous laminin distribution without Cre activation. No background eGFP signal ensures clean baseline imaging. Targets the widely expressed γ1 subunit, enhancing...
Published: 7/1/2026   |   Updated: 10/9/2025   |   Inventor(s): Yao Yao
Keywords(s): Animal Models, Neuroscience, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models
Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...
Published: 3/23/2023   |   Updated: 9/6/2018   |   Inventor(s): Chung-Jen (James) Chou, Ying Mei, Jia Jia
Keywords(s):  
Category(s): BioPharma
Novel Coronatine-Based Herbicide Treatment Platform with Increased Pathogen Resistance for Crop Plants
Executive SummaryDespite best efforts and current technology to enhance agricultural productivity, it’s estimated that insect pests and disease reduce the value of several major world crops, including rice, wheat, and corn by 20-37% annually. Considering more and more pests are becoming resistant to common agrochemical treatments, a crop plant...
Published: 8/20/2022   |   Updated: 8/29/2018   |   Inventor(s): Sheng-Yang He, Li Zhang, Jian Yao, Rahul Banerjee, John Withers
Keywords(s):  
Category(s): Agriculture, Biotechnology