Search Results - jason+so

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Circular Biological Experiment Platforms for Simulated Microgravity Experiments
Advantages Prevents air bubble formation, improving experimental reliability and reproducibility Integrated accelerometer enables real-time validation of simulated microgravity conditions Modular, interchangeable design supports multi-sample and higher-throughput testing Secure, leak-resistant mounting system compatible with standard 3D clinostats Summary Simulated...
Published: 3/9/2026   |   Inventor(s): Begum Mathyk, Stephanie Carey, Matthew Anderson, John Templeton, Jason Caouette
Keywords(s): 3D Printing, Laboratory Devices, Space and Exploration
Category(s): Technology Classifications > Engineering > Additive Manufacturing, Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications > Medical > Medical Devices, Technology Classifications > Engineering > Mechanical Engineering, Technology Classifications > Electronics > Electronics Sensors
APMBR (Anaerobic-Phototrophic Membrane Bioreactor)
Advantages High carbon removal efficiency (up to ~95% TOC and ~98% COD under nominal operation) Integrated biological and membrane filtration system with automated controls Produces nutrient-rich permeate suitable for hydroponic plant growth Compact, small-footprint design with low consumable requirements Demonstrated stable operation with resilience...
Published: 3/2/2026   |   Inventor(s): Daniel Yeh, Luke Roberson, Daniella Saetta, Jason Fischer, Lawrence Koss
Keywords(s): Water / Waste Treatment
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Energy & Environment > Energy Engineering, Technology Classifications > Energy & Environment
Fermentation Membrane Bioreactor for Biomanufacturing
Advantages Enables continuous, high-yield biomanufacturing beyond batch limitations Delivers real-time product extraction without interrupting fermentation Lowers operating costs by using waste-derived and alternative feedstocks Scales easily with automated control, ensuring consistent product quality Summary Traditional fermentation systems...
Published: 2/19/2026   |   Inventor(s): Daniel Yeh, Luke Roberson, Jason Fischer, Daniella Saetta, Alexandra Smith
Keywords(s): Biotechnology, Chemistry and Chemical Engineering, Energy Engineering, Renewable Energy
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Engineering > Chemical Engineering, Technology Classifications > Engineering > Manufacturing, Technology Classifications > Energy & Environment
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026   |   Inventor(s): A Departmental Work, Michael Brown
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
Engineered prefusion-stabilized RSV fusion proteins and nucleic acids for enhanced vaccines and diagnostics
This technology uses engineered RSV prefusion proteins with specific mutations to boost stability, expression, and shelf life, enabling more effective and affordable RSV vaccines, treatments, and diagnostics in both protein and nucleic acid (e.g., mRNA) formats. Background Respiratory Syncytial Virus (RSV) is a leading cause of severe respiratory...
Published: 1/27/2026   |   Inventor(s): Jason McLellan, Ajit Ramamohan, Jimmy Gollihar, Raghav Shroff, Thomas Segall-Shapiro, Shaunak Kar, Daniel Boutz, Andrew Horton, Nasim Abdi, Daniel Diaz
Keywords(s):  
Category(s): Life sciences > Therapeutics > Vaccines
Anticancer IgG Against Multiple Epitopes on Live Tumors Upon Disruption of ‘Self’ Signaling by CD47
A method to combine two or three monoclonal antibodies (mABs) into one treatment to successfully bind to multiple cancer cell surface epitopes and promote targeted degradation by phagocytosis. Problem: Phagocytosis of ‘self’ cells is generally inhibited by a key macrophage checkpoint interaction between SIRPα on the macrophage and...
Published: 12/15/2025   |   Inventor(s): Dennis Discher, Jason Andrechak, Lawrence Dooling
Keywords(s): Antibody, Bioengineering, Cell Therapy, Drug Target, Immunology, Immunoncology, Immunotherapy, Oncology, Platform Technology
Category(s): Technology Classifications > Therapeutics
THE APNEA ALARM: Biomarkers and a Device to Alarm when Risk of Death from Obstructive Apnea is Immediate
Analyzes electrocardiogram (ECG) data and sounds an alarm when two critical biomarkers exceed thresholds, enabling lifesaving intervention. Background: Epileptic seizures can cause laryngospasm sufficiently severe to produce complete airway obstruction. Once occluded, attempts to inhale against a closed airway get progressively stronger until attempts...
Published: 1/30/2026   |   Inventor(s): Mark Stewart, Richard Kollmar, Jason Lazar
Keywords(s): Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Healthcare IT, Technology Classifications > Medical Devices
Curative Locoregional Therapy Using Ablation or Catheter-Based Embolization of Targeted Hepatocellular Carcinoma by Delivering Supercharged NK Cells and CAR-NK or CAR-T Cells (UCLA Case No. 2023-115)
UCLA researchers in the School of Dentistry and Interventional Radiology have developed a groundbreaking curative treatment for hepatocellular carcinoma that combines locoregional therapy, such as ablation or catheter-based embolization, with targeted delivery of supercharged NK cells and CAR-NK or CAR-T cells, offering a highly effective approach that...
Published: 10/31/2025   |   Inventor(s): Anahid Jewett, Steven Raman, Jason Chiang
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy
High-Throughput Cell Screening With Interferometric Cytometry (Case No. 2007-720)
Summary The combined technology platform encompasses optical cytometry via interferometric membrane probing and cell mechanical / membrane property characterization, using reflective microparticles and interferometric imaging to measure deformation and viscoelastic response of live cells. The approach links physical membrane dynamics to cellular state,...
Published: 9/25/2025   |   Inventor(s): Michael Teitell, James Gimzewski, Jason Reed
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems
Molecular Regulation of Stroke-Resistant Neurons (UCLA Case No. 2020-937)
Researchers in the Department of Neurology at UCLA have identified pharmacologic compounds capable of crossing the blood brain barrier that dramatically promote neurite outgrowth after stroke, thereby promoting recovery. Background: A stroke occurs when the blood supply of oxygen is interrupted to the brain, preventing brain tissue from receiving oxygen...
Published: 10/8/2025   |   Inventor(s): Jason Hinman
Keywords(s):  
Category(s): Therapeutics > CNS and Neurology
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