Search Results - jason+so

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Curative Locoregional Therapy Using Ablation or Catheter-Based Embolization of Targeted Hepatocellular Carcinoma by Delivering Supercharged NK Cells and CAR-NK or CAR-T Cells (UCLA Case No. 2023-115)
UCLA researchers in the School of Dentistry and Interventional Radiology have developed a groundbreaking curative treatment for hepatocellular carcinoma that combines locoregional therapy, such as ablation or catheter-based embolization, with targeted delivery of supercharged NK cells and CAR-NK or CAR-T cells, offering a highly effective approach that...
Published: 10/23/2025   |   Inventor(s): Anahid Jewett, Steven Raman, Jason Chiang
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy
High-Throughput Cell Screening With Interferometric Cytometry (Case No. 2007-720)
Summary The combined technology platform encompasses optical cytometry via interferometric membrane probing and cell mechanical / membrane property characterization, using reflective microparticles and interferometric imaging to measure deformation and viscoelastic response of live cells. The approach links physical membrane dynamics to cellular state,...
Published: 9/25/2025   |   Inventor(s): Michael Teitell, James Gimzewski, Jason Reed
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems
Molecular Regulation of Stroke-Resistant Neurons (UCLA Case No. 2020-937)
Researchers in the Department of Neurology at UCLA have identified pharmacologic compounds capable of crossing the blood brain barrier that dramatically promote neurite outgrowth after stroke, thereby promoting recovery. Background: A stroke occurs when the blood supply of oxygen is interrupted to the brain, preventing brain tissue from receiving oxygen...
Published: 10/8/2025   |   Inventor(s): Jason Hinman
Keywords(s):  
Category(s): Therapeutics > CNS and Neurology
Scalable Van Der Waals Superlattices for Absorbers and Emitters (Case No. 2021-318)
Summary UCLA researchers have developed scalable Van der Waals superlattice materials designed as absorbers and emitters with tunable optical/electronic properties, enabling better control over thermal radiation or photonic emission across a range of wavelengths. Background Existing absorber and emitter materials for photonic and thermal applications...
Published: 10/1/2025   |   Inventor(s): Artur Davoyan, Deep Jariwala, Jason Lynch, Pawan Kumar, Francisco Barrera
Keywords(s):  
Category(s): Materials, Electrical, Electrical > Signal Processing, Materials > Semiconducting Materials
Novel MARK4 Inhibitors for Neurodegenerative Disorders (UCLA Case No. 2021-321)
UCLA researchers in the Department of Neurology have developed highly selective inhibitors of MARK4, aiming to revolutionize the treatment landscape for cancer and neurodegenerative disease through precise molecular targeting. BACKGROUND: MARK4 (Microtubule Affinity-Regulating Kinase 4) is a serine/threonine kinase from the AMP-activated protein...
Published: 9/10/2025   |   Inventor(s): Varghese John, Jason Hinman, Jesus Campagna
Keywords(s):  
Category(s): Therapeutics > CNS and Neurology
Liver Organoids with Multi-Lineage Cellular Repertoire
This invention is a human liver organoid model derived from induced pluripotent stem cells (iPSCs) that replicates the cellular complexity of the human liver. The system is designed to include multiple liver cell types, without genetic manipulation or animal derived matrices, enabling more accurate modeling of liver diseases such as Metabolic Dysfunction-Associated...
Published: 8/19/2025   |   Inventor(s): Jason Wertheim, Ekta Minocha, Ashwani Gupta, John Purdy, Nate Schmidt, Richard Green
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Life Sciences, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Simulators and Modeling Tools
Dual-Function Green Solvents and Monomers for Utilizing Waste Plastics in 3D Printing
The Problem: The increasing generation of plastic waste, such as polystyrene (PS), polymethyl methacrylate (PMMA), and polyvinyl chloride (PVC), poses an environmental challenge. Traditional methods for managing plastic waste (e.g. landfilling and incineration), have drawbacks such as environmental pollution and limited resource recovery. Mechanical...
Published: 8/8/2025   |   Inventor(s): Jason Bara, Zahra Sekhavat Pour, Sourav Chatterjee
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Manufacturing, Technology Classifications > Materials
Ionizable and Cationic Lipids with Components Derived From Glycerol
The Problem: The field of nucleic acid therapeutics depends critically on effective delivery systems to protect and transport the therapeutic into the target cells. Ionizable lipids are the key components in the state-of-the-art delivery systems for RNA. However, current major limitations include poor biodegradability, low thermostability, limited...
Published: 8/4/2025   |   Inventor(s): Jason Bara, Talia Shmool
Keywords(s):  
Category(s): Technology Classifications > Healthcare, Technology Classifications > Manufacturing
OPG153-based vaccine for targeted mpox immunization
Background The global re-emergence of monkeypox virus (MPXV) has created a critical need for effective and well-tolerated vaccines to prevent infection, limit disease severity, and reduce transmission. As an orthopoxvirus related to smallpox, mpox presents a unique public health challenge, especially for immuno­compromised populations. Current...
Published: 7/31/2025   |   Inventor(s): Jason McLellan, Ling Zhou, Emily Rundlet, Emanuele Andreano, Rino Rappuoli, Ida Paciello, Giulia Realini, Federica Perrone
Keywords(s):  
Category(s): Life sciences > Therapeutics > Vaccines
Production of Spin-Polarized Molecular Beams via Microwave or Infrared Rotational Excitation
Achieving high nuclear spin polarization in molecules is critical for enhancing the efficiency of nuclear fusion reactors and significantly boosting signals in nuclear magnetic resonance (NMR) and medical imaging. However, existing methods face substantial limitations in meeting the demand for large quantities of highly polarized molecules. Conventional...
Published: 7/29/2025   |   Inventor(s): Ahmed Diallo, Jason Parisi, Theodore Rakitzis, Chrysovalantis Kannis
Keywords(s): fusion
Category(s): Plasma/Fusion
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