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Search Results - jason+so
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Multi-Breath Nitrogen Washout Model for Lung Function Determination
The Lung Clearance Index (LCI) is a lung function parameter derived from the multi-breath washout (MBW) test. Although recent technological advances in equipment design have re-popularized this test, current analysis methods remain empirical and are dependent on the patient being able to breath regularly and deeply. This novel MBW data analysis method...
Published: 5/21/2025
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Inventor(s):
Jason Bates
Keywords(s):
Category(s):
Technology Classifications > Biomedical
Augmenting Vaccine Viral Production Using Late Domain Manipulation
Vaccines against infectious disease have dramatically decrease mortality and morbidity in the western hemisphere and have led to the eradication of small pox globally. Background: In order to expand this impact, the industry needs increased and improved vaccine development methods. Reduced production time and costs would significantly alter and impact...
Published: 5/21/2025
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Inventor(s):
Jason Botten
,
Emily Bruce
,
Christopher Ziegler
Keywords(s):
Category(s):
Technology Classifications > Biomedical
Optimization of ARDS Ventilation with Real-Time Respiratory Mechanics Monitoring
Diagnostic tool that uses a new mode of mechanical ventilation (variable ventilation) to optimize the management of patients with ARDS Background: Currently there are no drugs available for acute respiratory distress syndrome (ARDS), an often fatal condition, and the only treatment consists of supportive therapies, mainly mechanical ventilation. A...
Published: 5/21/2025
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Inventor(s):
Jason Bates
,
Bradford Smith
Keywords(s):
Category(s):
Technology Classifications > Biomedical
Disposable Impedance Adapter (DIA) for Ventilator Assessment of Respiratory Function
Assessment of respiratory mechanical function in patients on mechanical ventilators is done using a measurement of impedance on ventilator pressure and flow, but when a patient is partially breathing for themselves, accurate respiratory function measurements cannot be determined using these parameters. The DIA solves this problem by providing a controlled...
Published: 5/21/2025
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Inventor(s):
Jason Bates
Keywords(s):
Category(s):
Technology Classifications > Biomedical
Breath Biofeedback Video Game
Breath training and awareness using interactive, breath-controlled video games, with both diagnostic and therapeutic benefit Background: Breathing, relaxation and awareness training significantly ameliorates respiratory symptoms and dysfunctional breathing. In spite of these benefits, consistent, safe and effective delivery of breath training is difficult...
Published: 5/21/2025
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Inventor(s):
Jason Bates
,
Peter Bingham
,
Charles Irvin
,
Lennart Lundblad
Keywords(s):
Category(s):
Technology Classifications > Biomedical
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Technology Classifications > Information Technology > Software & Data
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Technology Classifications > Medical Device
Cardiac Defibrillation with Vagus Nerve Stimulation
A safer technique for treatment of ventricular fibrillation that can be used without the need for a separate defibrillator device. Background: Defibrillators restore a normal heartbeat, when the body experiences defibrillation, a condition in which the electrical activity of the heart becomes disorganized, preventing the heart from pumping blood. Defibrillators...
Published: 5/13/2025
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Inventor(s):
Mark Stewart
,
Isaac Naggar
,
Jason Lazar
Keywords(s):
TAF
,
Technologies
Category(s):
Technology Classifications > Medical Devices
,
Campus > SUNY Downstate Health Sciences University
Solvent System for Temperature Efficient Extraction of Pure Water from Saline Brine
The Problem: Desalination of high-salinity brine solutions, a byproduct of various industrial processes and seawater desalination, poses challenges due to inefficiencies and high energy consumption of conventional methods. Reverse osmosis struggles with fouling and scaling due to the high concentration of dissolved solids. Distillation is energy-intensive...
Published: 4/24/2025
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Inventor(s):
Steven Weinman
,
Jason Bara
,
Heath Turner
,
Gabriel Barbosa
Keywords(s):
Category(s):
Technology Classifications
,
Technology Classifications > Manufacturing
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Technology Classifications > Healthcare
Glycoprotein engineering for hemorrhagic fever virus vaccines
Scientists stabilized the Crimean-Congo hemorrhagic fever virus glycoprotein complex to study its structure and develop a potential vaccine. This complex elicits an immune response and sheds light on the virus's entry mechanism. Background Crimean-Congo hemorrhagic fever virus (CCHFV) is a serious threat to human health, with mortality rates ranging...
Published: 3/3/2025
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Inventor(s):
Jason McLellan
,
Elizabeth McFadden
Keywords(s):
Category(s):
Life sciences > Therapeutics > Vaccines
Anticancer IgG Against Multiple Epitopes on Live Tumors Upon Disruption of ‘Self’ Signaling by CD47
A method to combine two or three monoclonal antibodies (mABs) into one treatment to successfully bind to multiple cancer cell surface epitopes and promote targeted degradation by phagocytosis. Problem: Phagocytosis of ‘self’ cells is generally inhibited by a key macrophage checkpoint interaction between SIRPα on the macrophage and...
Published: 2/27/2025
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Inventor(s):
Dennis Discher
,
Jason Andrechak
,
Lawrence Dooling
Keywords(s):
Antibody
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Bioengineering
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Cell Therapy
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Drug Target
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Immunology
,
Immunoncology
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Immunotherapy
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Oncology
,
Platform Technology
Category(s):
Technology Classifications > Therapeutics
Laser apparatus for micro-volume tissue excision
This technology uses a laser to remove tiny pieces of tissue for analysis. The laser is shaped into a ring and can be combined with cooling techniques to minimize damage. Background The traditional histopathology workflow, while considered the gold standard for tissue diagnosis, suffers from several limitations. These include the invasiveness of biopsies,...
Published: 4/16/2025
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Inventor(s):
Thomas Milner
,
James Tunnell
,
Jason King
,
Nitesh Katta
Keywords(s):
Category(s):
Life sciences > Medical technology > Medical devices
,
Life sciences > Medical technology
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