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Scalable Van Der Waals Superlattices for Absorbers and Emitters (Case No. 2021-318)
Summary UCLA researchers have developed scalable Van der Waals superlattice materials designed as absorbers and emitters with tunable optical/electronic properties, enabling better control over thermal radiation or photonic emission across a range of wavelengths. Background Existing absorber and emitter materials for photonic and thermal applications...
Published: 9/11/2025
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Inventor(s):
Artur Davoyan
,
Deep Jariwala
,
Jason Lynch
,
Pawan Kumar
,
Francisco Barrera
Keywords(s):
Category(s):
Materials
,
Electrical
,
Electrical > Signal Processing
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Materials > Semiconducting Materials
Novel MARK4 Inhibitors for Neurodegenerative Disorders (UCLA Case No. 2021-321)
UCLA researchers in the Department of Neurology have developed highly selective inhibitors of MARK4, aiming to revolutionize the treatment landscape for cancer and neurodegenerative disease through precise molecular targeting. BACKGROUND: MARK4 (Microtubule Affinity-Regulating Kinase 4) is a serine/threonine kinase from the AMP-activated protein...
Published: 9/10/2025
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Inventor(s):
Varghese John
,
Jason Hinman
,
Jesus Campagna
Keywords(s):
Category(s):
Therapeutics > CNS and Neurology
Liver Organoids with Multi-Lineage Cellular Repertoire
This invention is a human liver organoid model derived from induced pluripotent stem cells (iPSCs) that replicates the cellular complexity of the human liver. The system is designed to include multiple liver cell types, without genetic manipulation or animal derived matrices, enabling more accurate modeling of liver diseases such as Metabolic Dysfunction-Associated...
Published: 8/19/2025
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Inventor(s):
Jason Wertheim
,
Ekta Minocha
,
Ashwani Gupta
,
John Purdy
,
Nate Schmidt
,
Richard Green
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity
,
Technology Classifications > Life Sciences
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Technology Classifications > Research Tools > Cell Lines
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Technology Classifications > Research Tools > Simulators and Modeling Tools
Dual-Function Green Solvents and Monomers for Utilizing Waste Plastics in 3D Printing
The Problem: The increasing generation of plastic waste, such as polystyrene (PS), polymethyl methacrylate (PMMA), and polyvinyl chloride (PVC), poses an environmental challenge. Traditional methods for managing plastic waste (e.g. landfilling and incineration), have drawbacks such as environmental pollution and limited resource recovery. Mechanical...
Published: 8/8/2025
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Inventor(s):
Jason Bara
,
Zahra Sekhavat Pour
,
Sourav Chatterjee
Keywords(s):
Category(s):
Technology Classifications
,
Technology Classifications > Manufacturing
,
Technology Classifications > Materials
Ionizable and Cationic Lipids with Components Derived From Glycerol
The Problem: The field of nucleic acid therapeutics depends critically on effective delivery systems to protect and transport the therapeutic into the target cells. Ionizable lipids are the key components in the state-of-the-art delivery systems for RNA. However, current major limitations include poor biodegradability, low thermostability, limited...
Published: 8/4/2025
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Inventor(s):
Jason Bara
,
Talia Shmool
Keywords(s):
Category(s):
Technology Classifications > Healthcare
,
Technology Classifications > Manufacturing
OPG153-based vaccine for targeted mpox immunization
Background The global re-emergence of monkeypox virus (MPXV) has created a critical need for effective and well-tolerated vaccines to prevent infection, limit disease severity, and reduce transmission. As an orthopoxvirus related to smallpox, mpox presents a unique public health challenge, especially for immunocompromised populations. Current...
Published: 7/31/2025
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Inventor(s):
Jason McLellan
,
Ling Zhou
,
Emily Rundlet
,
Emanuele Andreano
,
Rino Rappuoli
,
Ida Paciello
,
Giulia Realini
,
Federica Perrone
Keywords(s):
Category(s):
Life sciences > Therapeutics > Vaccines
Production of Spin-Polarized Molecular Beams via Microwave or Infrared Rotational Excitation
Achieving high nuclear spin polarization in molecules is critical for enhancing the efficiency of nuclear fusion reactors and significantly boosting signals in nuclear magnetic resonance (NMR) and medical imaging. However, existing methods face substantial limitations in meeting the demand for large quantities of highly polarized molecules. Conventional...
Published: 7/29/2025
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Inventor(s):
Ahmed Diallo
,
Jason Parisi
,
Theodore Rakitzis
,
Chrysovalantis Kannis
Keywords(s):
fusion
Category(s):
Plasma/Fusion
Spin-Polarized Fuels for Enhanced Tritium Burn Efficiency in Fusion Energy Systems
Magnetic confinement fusion power plants face a fundamental challenge in efficiently utilizing tritium fuel, a critical and limited resource. While increasing tritium burn efficiency (TBE)—the fraction of injected tritium that fuses—is desirable for fuel self-sufficiency and reducing inventory, existing approaches encounter an inherent trade-off:...
Published: 7/28/2025
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Inventor(s):
Jason Parisi
,
Ahmed Diallo
,
Jacob Schwartz
Keywords(s):
fusion
Category(s):
Plasma/Fusion
Multi-Breath Nitrogen Washout Model for Lung Function Determination
The Lung Clearance Index (LCI) is a lung function parameter derived from the multi-breath washout (MBW) test. Although recent technological advances in equipment design have re-popularized this test, current analysis methods remain empirical and are dependent on the patient being able to breath regularly and deeply. This novel MBW data analysis method...
Published: 5/21/2025
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Inventor(s):
Jason Bates
Keywords(s):
Category(s):
Technology Classifications > Biomedical
Augmenting Vaccine Viral Production Using Late Domain Manipulation
Vaccines against infectious disease have dramatically decrease mortality and morbidity in the western hemisphere and have led to the eradication of small pox globally. Background: In order to expand this impact, the industry needs increased and improved vaccine development methods. Reduced production time and costs would significantly alter and impact...
Published: 6/27/2025
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Inventor(s):
Jason Botten
,
Emily Bruce
,
Christopher Ziegler
Keywords(s):
Category(s):
Technology Classifications > Biomedical
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