Search Results - jason+so

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High-Throughput Cell Screening With Interferometric Cytometry (Case No. 2007-720)
Summary The combined technology platform encompasses optical cytometry via interferometric membrane probing and cell mechanical / membrane property characterization, using reflective microparticles and interferometric imaging to measure deformation and viscoelastic response of live cells. The approach links physical membrane dynamics to cellular state,...
Published: 7/23/2026   |   Updated: 7/23/2026   |   Inventor(s): Michael Teitell, James Gimzewski, Jason Reed
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems
Mithramycin prodrug nanoformulations for improved disease treatment
This technology introduces a novel nano-formulation of Mithramycin A designed to improve cancer treatment effectiveness while significantly reducing associated liver toxicity. Background: Mithramycin A (MithA) is a potent inhibitor of RNA synthesis that binds to DNA and has demonstrated effectiveness against a specific oncogene found in Ewing sarcoma,...
Published: 6/22/2026   |   Updated: 6/21/2026   |   Inventor(s): Juntao Luo, Jason Horton, Dandan Guo, Mei Yun Lin
Keywords(s): cancer therapy, nanomedicine, targeted drug delivery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Design and Synthesis
High-yield prefusion stabilized hPIV3 antigens for vaccine and diagnostic development
This technology uses novel amino acid substitutions to stabilize the human parainfluenza virus 3 fusion protein, enabling its use as a more effective vaccine antigen and diagnostic reagent by improving protein stability and expression. Background Human parainfluenza virus 3 (hPIV3) is a prevalent respiratory pathogen causing severe illness...
Published: 7/13/2026   |   Updated: 6/5/2026   |   Inventor(s): Jason McLellan, Patrick Byrne, Ching-Lin Hsieh, Elizabeth Blade
Keywords(s):  
Category(s): Life sciences > Diagnostic, Life sciences > Therapeutics > Vaccines
Engineered hantavirus glycoprotein complexes for enhanced vaccines, antibody discovery, and diagnostic applications
This technology uses engineered hantavirus glycoproteins stabilized in their prefusion form to create more effective vaccines, antibody therapies, and diagnostic tools, improving immune response, production efficiency, and shelf life for hantavirus prevention and detection. Background Hantaviruses are a group of zoonotic viruses that cause severe...
Published: 6/5/2026   |   Updated: 6/5/2026   |   Inventor(s): Jason McLellan, Elizabeth McFadden, Luqiang Guo, Yuna Shin, Jimmy Gollihar, Raghav Shroff, Thomas Segall-Shapiro, Shaunak Kar, Daniel Boutz, Andrew Horton
Keywords(s):  
Category(s): Life sciences > Therapeutics > Vaccines
Portable Perfusion Apparatus for Ex Vivo Tissue
A portable perfusion apparatus that cycles perfusate through ex vivo vertebrate tissues, enabling field deployment for preservation and training. Problem: Amputated extremities can lose viability before reattachment, especially in remote or traumatic settings. Existing perfusion machines may be too large for rapid deployment and are often limited to...
Published: 4/6/2026   |   Updated: 4/6/2026   |   Inventor(s): Edward Cantu, Rikesh Gandhi, Lawrence Levin, Jason Wink, Matthew Winterton
Keywords(s): Orthopedics, Surgery
Category(s): Technology Classifications > Medical Devices
Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 6/17/2026   |   Updated: 3/23/2026   |   Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays
Bubble‑Free Cell Culture System for Simulated Microgravity Research
CellPod is a disposable, bubble‑free cell culture container that makes simulated‑microgravity experiments reliable, repeatable, and far easier to run in everyday research labs. Advantages Prevents air bubble formation, improving experimental reliability and reproducibility Integrated accelerometer enables real-time validation of simulated microgravity...
Published: 6/22/2026   |   Updated: 3/9/2026   |   Inventor(s): Begum Mathyk, Stephanie Carey, Matthew Anderson, John Templeton, Jason Caouette
Keywords(s): 3D Printing, Laboratory Devices, Space and Exploration
Category(s): Technology Classifications > Engineering > Additive Manufacturing, Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications > Medical > Medical Devices, Technology Classifications > Engineering > Mechanical Engineering, Technology Classifications > Electronics > Electronics Sensors
APMBR (Anaerobic-Phototrophic Membrane Bioreactor)
Advantages High carbon removal efficiency (up to ~95% TOC and ~98% COD under nominal operation) Integrated biological and membrane filtration system with automated controls Produces nutrient-rich permeate suitable for hydroponic plant growth Compact, small-footprint design with low consumable requirements Demonstrated stable operation with resilience...
Published: 7/19/2026   |   Updated: 3/2/2026   |   Inventor(s): Daniel Yeh, Luke Roberson, Daniella Saetta, Jason Fischer, Lawrence Koss
Keywords(s): Water / Waste Treatment
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Energy & Environment > Energy Engineering, Technology Classifications > Energy & Environment
Fermentation Membrane Bioreactor for Biomanufacturing
Advantages Enables continuous, high-yield biomanufacturing beyond batch limitations Delivers real-time product extraction without interrupting fermentation Lowers operating costs by using waste-derived and alternative feedstocks Scales easily with automated control, ensuring consistent product quality Summary Traditional fermentation systems...
Published: 6/22/2026   |   Updated: 2/19/2026   |   Inventor(s): Daniel Yeh, Luke Roberson, Jason Fischer, Daniella Saetta, Alexandra Smith
Keywords(s): Biotechnology, Chemistry and Chemical Engineering, Energy Engineering, Renewable Energy
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Engineering > Chemical Engineering, Technology Classifications > Engineering > Manufacturing, Technology Classifications > Energy & Environment
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 6/17/2026   |   Updated: 2/9/2026   |   Inventor(s): A Departmental Work, Michael Brown
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
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