Search Results - andrew+horton

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Engineered hantavirus glycoprotein complexes for enhanced vaccines, antibody discovery, and diagnostic applications
This technology uses engineered hantavirus glycoproteins stabilized in their prefusion form to create more effective vaccines, antibody therapies, and diagnostic tools, improving immune response, production efficiency, and shelf life for hantavirus prevention and detection. Background Hantaviruses are a group of zoonotic viruses that cause severe...
Published: 6/5/2026   |   Updated: 6/5/2026   |   Inventor(s): Jason McLellan, Elizabeth McFadden, Luqiang Guo, Yuna Shin, Jimmy Gollihar, Raghav Shroff, Thomas Segall-Shapiro, Shaunak Kar, Daniel Boutz, Andrew Horton
Keywords(s):  
Category(s): Life sciences > Therapeutics > Vaccines
Engineered prefusion-stabilized RSV fusion proteins and nucleic acids for enhanced vaccines and diagnostics
This technology uses engineered RSV prefusion proteins with specific mutations to boost stability, expression, and shelf life, enabling more effective and affordable RSV vaccines, treatments, and diagnostics in both protein and nucleic acid (e.g., mRNA) formats. Background Respiratory Syncytial Virus (RSV) is a leading cause of severe respiratory...
Published: 1/27/2026   |   Updated: 1/27/2026   |   Inventor(s): Jason McLellan, Ajit Ramamohan, Jimmy Gollihar, Raghav Shroff, Thomas Segall-Shapiro, Shaunak Kar, Daniel Boutz, Andrew Horton, Nasim Abdi, Daniel Diaz
Keywords(s):  
Category(s): Life sciences > Therapeutics > Vaccines