Search Results - raghav+shroff

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Human enzyme-mediated depletion of serine in cancer
Engineered human serine dehydratase enzymes are designed to efficiently degrade serine, an amino acid crucial to cancer cell metabolism, and inhibit cancer growth. These enzymes, with improved stability, activity, and bio­availability, offer a targeted cancer treatment option with fewer adverse effects. Background Traditional chemotherapeutic...
Published: 8/29/2024   |   Inventor(s): Everett Stone, Ebru Cayir, Daniel Diaz, Raghav Shroff
Keywords(s):  
Category(s): Life sciences > Therapeutics > Small molecule, Life sciences > Research tools
Bacterial reagents: stable, low-cost, readily available reagents with no purification requirements
Problem Most molecular biology techniques commonly used in research, biotechnology, healthcare, and education rely heavily on purified functional protein reagents. However, purification of these protein reagents requires substantial investment of time, expertise, equipment, and infrastructure. As a result, this significantly limits the availability...
Published: 11/1/2023   |   Inventor(s): Andrew Ellington, Sanchita Bhadra, Arti Pothukuchy, Michelle Byrom, Raghav Shroff, Jared Ellefson, Jimmy Gollihar
Keywords(s): Diagnostics, Isothermal amplification, Nucleic acid amplification, Point-of-need
Category(s): Life sciences > Research tools > Reagent, Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Therapeutics > Synthetic biology