Search Results - hening+lin

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Summary The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a class of novel aplithianine-derived small molecule analogs that compete with ATP for binding on a range of clinically relevant kinases including: Oncogenic gene fusion DNAJB1-PRKACA (PKADJ) Wild type protein kinase A (PKA) Protein kinase...

Published: 11/4/2024 | Inventor(s): Barry O'Keefe, Lin Du, Brice Wilson, Ping Zhang, William Moore, Dongdong Wang, Juliana Martinez Fiesco, Ning Li

Keywords(s):

Category(s): Application, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Rare / Neglected Diseases, TherapeuticArea > Infectious Disease

Reverse Thiazine Kinase Inhibitors

Published: 10/30/2024 | Inventor(s): Barry O'Keefe, Lin Du, Brice Wilson, Ping Zhang, William Moore, Dongdong Wang, Juliana Martinez Fiesco, Ning Li

Keywords(s):

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, TherapeuticArea > Rare / Neglected Diseases

Novel Kinase Inhibitory Aplithianines

Published: 10/30/2024 | Inventor(s): Barry O'Keefe, Lin Du, Brice Wilson, Ping Zhang, William Moore, Dongdong Wang, Juliana Martinez Fiesco, Ning Li

Keywords(s):

Category(s): Application > Therapeutics, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, TherapeuticArea > Rare / Neglected Diseases, Collaboration Sought > Collaboration

A Small Molecule Inhibitor Selective for HDAC11

HDAC11 is an enzyme which belongs to the Histone Deacetylase (HDAC) class of enzymes. However, HDAC11 has a high defatty-acylase activity while its deacetylation activity is virtually nonexistent. The defatty-acylase activity of HDAC11 is linked to increased interferon I signaling, suggesting that inhibition of HDAC11 can be used to treat diseases...

Published: 8/6/2024 | Inventor(s): Edward Seto, Hening Lin, Thanh Ho

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Small Molecules

Self-neutralizing air-breathing thruster and method of neutralization

An ion-engine is the cutting edge for atmospheric air-breathing engines. The technology depends on ionizing and neutralizing atmospheric air particles which create thrust. This unique possibility makes it an ideal choice for very-low-orbit satellites. Very- low-orbit satellite capabilities have benefits such as higher resolution for images, weight...

Published: 7/30/2024 | Inventor(s): Michael Keidar, Anmol Taploo, Li Lin

Keywords(s):

Category(s): Technology Classifications > Computers Electronics & Software, Technology Classifications > Computers Electronics & Software > Aviation, Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment, Technology Classifications > Industrial or Consumer Tech > Industrial Manufacturing

Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors

Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...

Published: 7/30/2024 | Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Cold atmospheric plasma-stimulated media for treating cancers

For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...

Published: 7/30/2024 | Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics

New Nanoink Formulation of Copper-based Nanowires with Dendrite-Like Decoration for Room-Temperature Sintering to Produce Conductive Traces on Flexible Polymeric Substrates

An air-stable and low-cost copper-based nanowire ink formulation for manufacturing wearable electronics and sensors on flexible polymer or paper substrates. Technology Overview: This new technology features an air-stable and low-cost copper-based nanowire ink formulation for manufacturing wearable electronics and sensors on flexible polymer or...

Published: 5/20/2024 | Inventor(s): Chuan Jian Zhong, Shan Yan, Ning He

Keywords(s): #SUNYresearch, CleanTech, Technologies, XCEED

Category(s): Technology Classifications > Clean Energy, Technology Classifications > Electronics, Campus > Binghamton University

Physics-based Machine-learning Approach for Tropical Cyclone Risk Analysis

Generating synthetic tropical cyclones is a general approach for assessing tropical cyclone hazards and risk applied by the government, wind engineering consultant labs, catastrophic modeling companies, and insurance companies. However, most methods currently in use can generate only storms under the observed climate conditions, as these models are...

Published: 11/14/2023 | Inventor(s): Ning Lin, Renzhi Jing, Dazhi Xi

Keywords(s):

Category(s): Computer Science and Information Technology

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