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Search Results - edward+seto
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A Novel Selective HDAC11 Inhibitor with Broad Anti-Cancer Efficacy
HDAC11 is a Histone Deacetylase (HDAC) enzyme. However, HDAC11 has a high defatty-acylase activity while its deacetylation activity is virtually nonexistent, which is linked to poor prognosis in multiple cancers. This suggests that inhibition of HDAC11 can be used to treat cancers by modulating protein function. No potent and selective inhibitors for...
Published: 4/29/2025
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Inventor(s):
Edward Seto
,
Hening Lin
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Small Molecules