Search Results - ning+he

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This invention is a reference-free snapshot wavefront camera that can be used to measure both amplitude and phase of the wavefront. The camera uses a two-dimensional diffraction grating to split the incoming wavefront into multiple copies which then travel through a lens that focuses them onto a sensor in a camera array. The resulting wavefront information...

Published: 7/2/2025 | Inventor(s): David Brady, Ni Chen, Shengtai Zhu, Gregory Nero

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Imaging & Optics > Ophthalmology

Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay

Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...

Published: 1/20/2026 | Inventor(s): Yong Zeng, He Yan

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics

Novel Kinase Inhibitory Thiazines

Summary The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a class of novel aplithianine-derived small molecule analogs that compete with ATP for binding on a range of clinically relevant kinases including: Oncogenic gene fusion DNAJB1-PRKACA (PKADJ) Wild type protein kinase A (PKA) Protein kinase...

Published: 10/28/2025 | Inventor(s): Barry O'Keefe, Lin Du, Brice Wilson, Ping Zhang, William Moore, Dongdong Wang, Juliana Martinez Fiesco, Ning Li

Keywords(s):

Category(s): Application, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, TherapeuticArea > Rare/Neglected Diseases

Reverse Thiazine Kinase Inhibitors

Published: 10/28/2025 | Inventor(s): Barry O'Keefe, Lin Du, Brice Wilson, Ping Zhang, William Moore, Dongdong Wang, Juliana Martinez Fiesco, Ning Li

Keywords(s):

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, TherapeuticArea > Rare/Neglected Diseases

Novel Kinase Inhibitory Aplithianines

Published: 10/28/2025 | Inventor(s): Barry O'Keefe, Lin Du, Brice Wilson, Ping Zhang, William Moore, Dongdong Wang, Juliana Martinez Fiesco, Ning Li

Keywords(s):

Category(s): Application > Therapeutics, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Rare/Neglected Diseases

Affinity measurement and sequencing of T cell receptor

The technology enables the measurement of T cell receptor (TCR) affinity and sequencing of antigen-specific T cells using a micropipette adhesion assay and single-cell paired TCRα/TCRβ sequencing. The method isolates antigen-specific T cells, measures TCR affinity, and determines TCR sequences for applications in immunotherapy and monitoring...

Published: 1/13/2026 | Inventor(s): Ning Jiang, Shuqi Zhang, Keyue Ma, Chenfeng He

Keywords(s):

Category(s): Life sciences > Immunology, Life sciences > Research tools > Tool/assay/screening platform

High-throughput sequencing technology for T-cell receptor specificity

TetTCR-seq is a method for high-throughput pairing of T cell receptor (TCR) sequences with their specific antigens using DNA-barcoded pMHC tetramers, enabling rapid, cost-effective immune profiling, disease diagnosis, and therapeutic development. Background The identification of antigen-specific T-cell receptors (TCRs) is crucial for understanding...

Published: 1/13/2026 | Inventor(s): Ning Jiang, Shuqi Zhang, Chenfeng He, Keyue Ma, Alexandra Schonnesen

Keywords(s):

Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Immunology

Identification of a Novel Parvovirus for Vaccine Development and Use as a Diagnostic Tool

This technology includes a procedure for novel virus identification in a variety of human specimens by solexa high-throughput sequencing, which allows for the screening a large number of clinical specimens for novel virus discovery in a highly efficient and relatively economical method. By using this technique, we have successfully identified a novel...

Published: 9/5/2024 | Inventor(s): Ning Zhi, Neal Young, Baoyan Xu, Keji Zhao, Gangqing Hu

Keywords(s):

Category(s): Application > Diagnostics, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease

Micro-Trenches That Retain Trapped Gas Under High-Speed Water Flows (UCLA Case No. 2023-204)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a design of microstructured surfaces capable of retaining air pockets under water at flow speeds above 10 knots so that watercraft can travel with a reduced drag. Background: A major challenge limiting efficiency and speed of watercraft is the friction...

Published: 7/17/2025 | Inventor(s): CJ Kim, Ning Yu

Keywords(s): boats, Drag (Physics), drag reduction, fluid mechanics, friction reduction, fuel efficiency, hull, Hydrophobic, liquid-air interface, marine applications, maritime, microtrenches, navy, planing hull, Seawater, ships, Superhydrophobic, water sports, watercraft

Category(s): Mechanical, Materials

Parvovirus B19 Vaccine

Parvovirus B19 (B19V) infection causes fifth disease, a disease characterized by rashes to the face and other parts of the body that primarily affects children. However, adults can also develop fifth disease and it can lead to more severe conditions. Patients that are immunocompromised, such as those who are HIV infected, organ transplant recipients,...

Published: 10/28/2024 | Inventor(s): Neal Young, Sachiko Kajigaya, Takashi Shimada, Ning Zhi

Keywords(s): Admin Lic Spec Review Mar-09 Active Determina, AgainstB19V, B19, B19V, BBXXXX, CAPSID, Capsids, CODON, CRADA, DA4BXX, DA4XXX, DAXXXX, DC5BXX, DC5XXX, DCXXXX, diagnostic, DNA-based, DXXXXX, GENES, Infection, Non-pennissive, PARTICLE, PARVOVIRUS, Patent Category - Biotechnology, SACGHS DNA Patent Initial Set, UA1XXX, VACCCINE, vaccines, VIRUS-LIKE, VLP-and

Category(s): Collaboration Sought > Collaboration, Application > Vaccines, TherapeuticArea > Infectious Disease, Application > Diagnostics, TherapeuticArea > Rare/Neglected Diseases

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