Search Results - jin-xiong+she

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Controlled Tunnel Gap Device for Sequencing Polymers
To reduce costs and increase the availability of personalized genomics new approaches to DNA sequencing are required. Nanopore sequencing is one proposed technique. In nanopore sequencing, DNA molecules are forced through a tiny aperture by electrophoresis. As the individual bases transit the nanopore, their identity can be determined, in theory, by...
Published: 8/22/2024   |   Inventor(s): Stuart Lindsay, Shuai Chang, Jin He, Peiming Zhang, Shuo Huang
Keywords(s): Bio-Technology
Category(s): Life Science (All LS Techs)
DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules
The US Government’s pursuit of the “Thousand Dollar Genome” and the “X Prize” goal of even lower cost DNA sequencing are striking examples of the importance being assigned to advances in methods for the DNA sequencing of the human genome. The first technology that finally allows for truly routine genome sequencing will...
Published: 8/22/2024   |   Inventor(s): Stuart Lindsay, Colin Nuckolls, Jinyao Tang, Jin He, Peiming Zhang, Kevin Reinhart
Keywords(s):  
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Proteomic Assays/Reagents/Tools
DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules
The US Government's pursuit of the "Thousand Dollar Genome" and the "X Prize" goal of even lower cost DNA sequencing are striking examples of the importance being assigned to advances in methods for the DNA sequencing of the human genome. The first technology that finally allows for truly routine genome sequencing will open a new...
Published: 8/22/2024   |   Inventor(s): Stuart Lindsay, Jin He, Peiming Zhang, Kevin Reinhart
Keywords(s):  
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools
A Transcriptomic Classifier of Gliomas
The current state of the art:Gliomas account for about 27% of all brain tumors and about 80% of the malignant tumors. Currently, Glioma is classified by histology and the gene mutation test (isocitrate dehydrogenase, IDH) defined by the world health organization (WHO).The problems with the current art:However, there is a big discrepancy between histology...
Published: 4/7/2023   |   Inventor(s): Jin-Xiong She, Paul Tran
Keywords(s):  
Category(s): Diagnostics
A Novel SUMO-like Gene for Type 1 Diabetes Susceptibility
Current State of the Art: Type 1 diabetes is an organ-specific autoimmune disease with aberrant immune responses to specific β-cell autoantigens. Prevention is important because diabetes interrupts normal development in children and carries the threat of severe complications in the most active period of life. Both environmental and genetic...
Published: 4/28/2020   |   Inventor(s): Jin-Xiong She, Cong-Yi Wang
Keywords(s): Diabetes II, Genomics
Category(s): Diagnostics
Stat5b transgenic lymphoma mouse model and therapeutic strategies
Current State of the Art:Based on the age of the patient and the stage of lymphoma different regimens of radiation and chemotherapy are employed. In regard to drugs, most patients with early stage lymphoma are treated with a cocktail called "ABVD" chemotherapy, which contains the drugs Adriamycin (doxorubicin), bleomycin, vinblastine and dacarbazine....
Published: 8/13/2019   |   Inventor(s): Jin-Xiong She, Bo Chen
Keywords(s):  
Category(s): Therapeutics
Novel synergistic combinations for cancer therapy
AU researchers have discovered several drug resistance genes that can be potentially used as therapeutic targets for cancer treatment. We also describe synergistic combinations between these genes and a large number of anticancer drugs that have been approved by the FDA for clinical use or clinical trials. Therefore, these genes alone or in combination...
Published: 11/12/2021   |   Inventor(s): Jin-Xiong She, Robert Schleifer, Shuchun Li
Keywords(s):  
Category(s): Therapeutics