Search Results - daniel+bliss

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Vital Signs Monitoring using Depth Cameras
Cardiovascular disease is responsible for an estimated 17.9 million deaths each year, making it the leading cause of death worldwide. Continuous heart health monitoring way is the best preventative for heart failure. However, standard monitoring devices, including ECG and PPG, require direct physical contact, which can be difficult for certain patient...
Published: 9/24/2024   |   Inventor(s): Yu Rong, Daniel Bliss
Keywords(s):  
Category(s): Computing & Information Technology, Medical Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Medical Imaging
UAV System with Vital Sign Sensing, Communications, and Positioning Estimation
When searching for missing persons, especially during emergency situations, such as catastrophic weather and infrastructure or geologic events, aerial reconnaissance can be an invaluable tool, particularly if the area is large and/or unstable. Unmanned aerial vehicles (UAVs) with thermal imaging capabilities can help detect heat signatures from victims,...
Published: 7/11/2024   |   Inventor(s): Daniel Bliss, Alex Chiriyath, Arindam Dutta, Andrew Herschfelt, Yu Rong
Keywords(s):  
Category(s): Intelligence & Security, Computing & Information Technology, Imaging, Life Science (All LS Techs), Wireless & Networking
Hybrid In-Situ & Signal of Opportunity Calibration for Antenna Arrays
Modern day aircrafts rely on a plethora of communications and navigation systems to enable secure and reliable flight operations. These systems are designed in isolation and physically separated to prevent interference between services. These choices lead to stove-pipe designs that lack backward compatibility. As a direct consequence, exteriors of...
Published: 3/29/2024   |   Inventor(s): Sharanya Srinivas, Daniel Bliss
Keywords(s): Algorithm Development, Communication, Navigation and Surveillance (CNS), Communications Systems
Category(s): Physical Science, Computing & Information Technology
Vision Guided Radar System for Enhanced Vital Signs Detection
Vital signs, such as heart and respiratory rate, provide critical insight into a person’s health. Radar has been used to remotely analyze and detect human activity and vital signs for many years. Despite all the great features such as motion sensitivity, privacy preservation, penetrability, and more, radar has limited spatial degrees of freedom...
Published: 2/16/2024   |   Inventor(s): Yu Rong, Shuaifeng Jiang, Ahmed Alkhateeb, Daniel Bliss
Keywords(s):  
Category(s): Intelligence & Security, Life Science (All LS Techs), Wireless & Networking, Computing & Information Technology, Medical Devices
High Affinity Nanobodies Targeting B7-H3 (CD276) for Treating Solid Tumors
Abstract: CD276 (also called B7-H3) is a pan-cancer antigen expressed in multiple solid tumors and an emerging cancer target. CD276 protein is overexpressed in pancreatic cancer, prostate cancer, breast cancer, colon cancer, lung cancer, and brain tumors (such as neuroblastoma) – making it an ideal target for cancer therapy.  Investigators at the National...
Published: 5/21/2024   |   Inventor(s): Mitchell Ho, Brad St. Croix, Ruixue Wang, Dan Li
Keywords(s): ADC, Antibody-drug Conjugate, B7-H3, BREAST CANCER, CAR, CD276, chimeric antigen receptor, COLON CANCER, Glioma, HO, lung cancer, Nanobodies, Neuroblastoma, OVARIAN CANCER, Pancreatic Cancer, solid tumors
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology
Combination of recombinant IL-7 with Chimeric Antigen Receptor (CAR) T Cells Targeting Glypican-3 (GPC3) for the Treatment of Hepatocellular Carcinoma (HCC)
Abstract: Hepatocellular carcinoma (HCC) is the most common type of liver cancer. standard treatment for HCC is not suitable for a large proportion of liver cancer patients. As a result, alternative treatments are needed. Chimeric antigen receptor (CAR) T cell therapy is a promising alternative approach selectively targets targeting tumors via tumor-specific...
Published: 5/21/2024   |   Inventor(s): Mitchell Ho, Dan Li, Byung Ha Lee, Sara Ferrando-Martinez
Keywords(s): CAR, Chimeric Antigen Receptor T Cell Therapy, Glypican-3, GPC-3, HCC, hepatocellular carcinoma, HO, Interleukin-7, liver, Recombinant IL-7, Tumor Specific Antigen
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology, Application > Therapeutics
New Chimeric Antigen Receptor (CAR) Format for Developing Improved Adoptive Cell Therapies
Abstract: Adoptive cell therapy (ACT) is an attractive new therapeutic approach for treating various cancers. ACT has recently demonstrated a high degree of efficacy when treating patients with hematological malignancies. However, to date, no effective Chimeric Antigen Receptors (CAR) T cell therapy exists for solid tumors. Researchers in the National...
Published: 5/21/2024   |   Inventor(s): Mitchell Ho, Nan Li, Dan Li
Keywords(s): CANCER, chimeric antigen receptor (CAR), GPC2, GPC3, HO, MESOTHELIN, solid tumor, tumor antigen
Category(s): Application > Therapeutics, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology
Cross Species Single Domain Antibodies Targeting PD-L1 for Treating Solid Tumors
Abstract: Programed Death-Ligand 1 (PD-L1, also known as B7-H1 or CD274) is a cell surface protein that binds to Programmed Cell Death Protein 1 (PD-1, also known as CD279). An imbalance in PD-1/PD-L1 activity contributes to cancer immune escape.  PD-1 is expressed on the surface of antigen-stimulated T cells. The interaction between PD-L1 and PD-1...
Published: 4/8/2024   |   Inventor(s): Mitchell Ho, Glenn Merlino, Dan Li, Hejiao English, Chi-Ping Day
Keywords(s): adoptive cell therapy, Chimeric Antigen Receptor T Cells, HO, ICI, Immune Checkpoint Inhibitor, Immunotherapy, NANOBODY, PD-L1, phage display, Programed Death-Ligand, Single Domain Antibody
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, Collaboration Sought > Licensing, TherapeuticArea > Oncology
Joint Positioning-Communications: Constant Information Ranging for Dynamic Spectrum Access
­Spectral congestion limits the opportunities and performance of radio frequency (RF) systems. Every RF device must share limited spectral resources, which becomes increasingly challenging as more devices are introduced into congested environments. Modern RF technologies must be supported by efficient resource management strategies and cooperation...
Published: 2/23/2023   |   Inventor(s): Sharanya Srinivas, Daniel Bliss
Keywords(s): Communication, Navigation and Surveillance (CNS), Communications Systems, Positioning, Positioning, Navigation and Timing (PNT), Vehicle-to-Vehicle
Category(s): Computing & Information Technology, Physical Science, Wireless & Networking
User-Space Emulation Framework for Domain-Specific Soc Design
This technology uses Linux-based emulation framework to provide an ecosystem for hardware-software co-design of Domain-specific SoCs (DSSoCs) and enable their rapid evaluation during the pre-silicon design phase. Background: As technology scaling becomes a challenge, System-on-chip architects are exploring DSSoCs to effectively balance performance...
Published: 8/1/2024   |   Inventor(s): Umit Ogras, Radu Marculescu, Ali Akoglu, Chaitali Chakrabarti, Daniel Bliss, Samet Egemen Arda, Anderson Luiz Sartor, Nirmal Kumbhare, Anish Krishnakumar, Joshua Mack, Ahmet Alper Goksoy, Sumit Kumar Mandal
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Computer-Aided Design & Engineering
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