Search Results - dan+wheeler+patterson

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Immunotherapy That Converts Glioblastoma Cells Into Immune Cells to Attack Cancerous Tumors
Converts Cancer Cells to Immune Cells that Recruit Body’s Own Immune System to Target Brain Tumors This immunotherapy directly reprograms cancer cells into immune cells, specifically dendritic cells, making the reprogrammed cancer cells a therapy for the rest of the tumor. Glioblastoma (GBM) is the most common and lethal brain cancer in adults....
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Human Health Care > Gene Therapy
Structures and Methods for Design Automation of Radiation Hardened Triple Mode Redundant Digital Circuits
Protecting high performance integrated circuits (ICs) from ionizing radiation induced upset is a key issue in the design of microcircuits for applications such as spacecraft, high altitude aircraft, and around nuclear accidents or nuclear warfare. A radiation induced soft error occurs in a semiconductor device when a high-energy particle travels...
Published: 2/23/2023   |   Inventor(s): Lawrence Clark, Nathan Hindman, Dan Wheeler Patterson
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Physical Science
Liquid Biopsy Screening for Early Detection of Cancers in Patients
Highly Sensitive, Specific and Low Cost Method of Detecting Cancer in Bodily Fluids by Analyzing the Accessibility and Expression of Cancer Master Gene RegulatorsThis non-invasive method of liquid biopsy screening much more sensitively and specifically detects cancer in patients, including those with rare or novel mutations with cost in the order of...
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics
Adaptive System that Records Cellular Lineage, Cellular Clock, and Cellular Memory Simultaneously
Diary Reveals a Comprehensive History of a Cell that Aids Research, Diagnostics, and TherapeuticsThis molecular cell diary system is capable of creating a detailed understanding of a cell’s history and current state, including its cellular lineage, cellular clock, and cellular memory. The molecular diagnostics market in 2014 was globally worth...
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s): cellular barometer, cellular clock, cellular events tracking, cellular memory, lineage tracing, mutational history
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Research Tools > Diagnostics, Technology Classifications > Research Tools > Others, Technology Classifications > Research Tools > Vectors, Technology Classifications > Software > Others
Algorithm for Ranking Master Regulators in Gene Networks
Bioinformatics Program Quantifies Influence by Assigning Importance Scores to Nodes in NetworksThis network ranking system uses a computational algorithm based on a set of parameters to generate an importance score for each node in a network, thereby establishing the means to rank and identify master regulators, in particularly transcription factors,...
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s): computational biology, master regulator ranking, node scoring, random network generation, Software
Category(s): Technology Classifications > Software > Others
Glioblastoma Stem Cell Regulators with Therapeutic Potential
Targets Crucial Cancer Stem Cell Factors to Inhibit Glioblastoma Growth This combination of cancer master regulators enables targeting glioblastoma (GBM) stem cells to inhibit their growth. According to the National Brain Tumor Society, only 5.5 percent of patients suffering from GBM survive five or more years after diagnosis, due to rapid cell growth...
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s): cancer drug targets, GBM, GBM stem cells, Glioblastoma, master regulators, stemness
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Human Health Care > Therapeutics
Design Automation of Radiation Hardened Mixed Single, Dual, and Triple Mode Redundant Digital Circuits
The fundamental building blocks of all computer electronics, integrated circuits (ICs) are the least expensive way to create the digital circuits needed for processing binary information. A soft error is when a binary switch within a digital circuit flips to its opposite state and causes an electronic device to malfunction. Modular redundancy is a method...
Published: 2/23/2023   |   Inventor(s): Lawrence Clark, Dan Wheeler Patterson, Chandarasekaran Ramamurthy, Srivatsan Chellappa
Keywords(s): Circuits, Integrated Circuits, Ionizing Radiation, Radiation Hardening
Category(s): Semiconductor Devices