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Search Results - can+korman
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Reliable Liquid Metal Composites for Soft Robotics, Electronics, and Thermal Management
This invention introduces oxide-flake-stabilized liquid metal powders that suppress supercooling, enabling reliable phase transitions for tunable stiffness, thermal management, and adaptive devices. Background: Liquid metal (LM)-based composites are promising for tunable stiffness, shape memory, and thermal management applications in robotics, electronics,...
Published: 9/9/2025
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Inventor(s):
Pu Zhang
,
Jiexian Ma
Keywords(s):
CleanTech
Category(s):
Campus > Binghamton University
,
Technology Classifications > Engineering
LNP + Squeeze: Enhancing Chimeric Antigen Receptor T-Cell Generation via Mechanoporation and Lipid Nanoparticles
Synergistic combination of mechanoporation and lipid nanoparticle (LNP) based transfection for an efficient, non-viral method of gene transfer to generate CAR-T cell therapies. Problem: Chimeric antigen receptor (CAR)-T cell therapy has transformed cancer treatment by engineering patients' T cells to precisely target and eradicate cancer cells....
Published: 8/28/2025
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Inventor(s):
Jina Ko
,
Jianhua Lim
Keywords(s):
Bioengineering
,
Cell Therapy
,
Gene Editing
,
Immunology
,
Immunoncology
,
Microfluidics
,
Nanotechnology
Category(s):
Technology Classifications > Research Tools & Reagents
,
Technology Classifications > Therapeutics
,
Technology Classifications > Chemical Processes and Synthesis
Ampule-Based Synthesis of Sulfur-Porous Carbon Composites for Lithium-Sulfur Batteries
Background Lithium/sulfur (Li/S) batteries are garnering significant attention as a promising solution for next-generation electrochemical energy storage. Their potential to revolutionize the battery industry stems from several key advantages that address the limitations of current lithium-ion (Li-ion) technology. These advantages include an exceptionally...
Published: 8/21/2025
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Inventor(s):
Yoon Hwa
,
David Wright
,
Yuhui An
Keywords(s):
Chemicals
,
Energy storage
,
Engineering
,
Materials
,
Nanomaterials
,
Synthesis
Category(s):
Energy & Power
,
Physical Science
,
Advanced Materials/Nanotechnology
,
Semiconductors, Materials & Processes
A conserved viral peptide for use in cancer immunotherapy
Summary: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for viral peptide (CE1)-based therapeutics for HCC prevention and treatment. Description of Technology: Hepatocellular carcinoma (HCC) is a common and aggressive primary liver cancer. It develops mainly from at-risk individuals with underlying chronic...
Published: 8/21/2025
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Inventor(s):
Xin Wei Wang
,
Lichun Ma
,
Man Hsin Hung
Keywords(s):
Category(s):
TherapeuticArea > Oncology
,
Application > Therapeutics
,
Collaboration Sought > Licensing
,
Collaboration Sought > Collaboration
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025
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Inventor(s):
Stephen Liggett
,
Donghwa Kim
,
Yu Chen
,
Jesper Madsen
,
Steven An
Keywords(s):
Pharmaceuticals
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
A novel approach to the treatment of EGFR mutant non-small cell lung cancer (NSCLC)
Background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for ~85% of all lung cancer cases. NSCLC is slow growing and often diagnosed at later stages when it has already spread, making treatment difficult. Resistance to therapy is a major challenge in effectively treating patients with NSCLC. 10-30% of...
Published: 8/14/2025
|
Inventor(s):
Jack Elias
,
Suchitra Kamle
,
Chun Geun Lee
,
Bing Ma
Keywords(s):
Category(s):
Oncology
Functional Hierarchical Porous Organic Polymers for Water Purification
Advantages: High absorption capacity Fast and controllable kinetics Facile regeneration and recyclability Stable under a wide range of conditions High density of chelating sites Summary: Water and energy purification are important factors in minimizing the harsh impact of technology on the environment. Coal-powered fuel stations and waste...
Published: 3/4/2025
|
Inventor(s):
Shengqian Ma
,
Qi Sun
,
Briana Aguila
Keywords(s):
Category(s):
Technology Classifications > Energy & Environment
Gaseous Crosslinker for Binder Jetting of Strong Green Parts
Background Due to the current climate crisis, the US has deployed a financial incentive of $130-180 per ton of CO2 removed using direct air capture (DAC) technology. DAC is a form of CO2 removal from the air. There are many different methods of creating materials for DAC. Binder jetting is a 3D printing manufacturing process capable of producing...
Published: 2/20/2025
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Inventor(s):
Chao Ma
Keywords(s):
Category(s):
Advanced Materials/Nanotechnology
,
Physical Science
,
Manufacturing/Construction/Mechanical
Crosslinker for Binder Jetting of Strong Green Parts
Background Due to the current climate crisis, the US has deployed a financial incentive of $130-180 per ton of CO2 removed using direct air capture (DAC) technology. DAC is a form of CO2 removal from the air. There are many different methods of creating sorbents for DAC. Binder jetting is a 3D printing manufacturing process capable of producing...
Published: 2/20/2025
|
Inventor(s):
Chao Ma
Keywords(s):
Category(s):
Physical Science
,
Manufacturing/Construction/Mechanical
,
Advanced Materials/Nanotechnology
Chemical Grafting Agent for Binder Jetting of Strong Green Parts
Background Due to the current climate crisis, the US has deployed a financial incentive of $130-180 per ton of CO2 removed using direct air capture (DAC) technology. DAC is a form of CO2 removal from the air. There are many different methods of creating sorbents for DAC. Binder jetting is a 3D printing manufacturing process capable of producing...
Published: 2/20/2025
|
Inventor(s):
Chao Ma
Keywords(s):
Category(s):
Advanced Materials/Nanotechnology
,
Physical Science
,
Manufacturing/Construction/Mechanical
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