Search Results - benjamin+miller

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RNA-Targeted Small Molecules as Potential Antiviral Therapy (HIV, SARS etc)
Brief Description: A high error rate of HIV -I reverse transcriptase coupled with a fast replication cycle associated with HIV -1 favors rapid development and selection of drug resistant strains. Therefore, identification of small molecules capable of inhibiting viral components necessary for HIV -1 proliferation continues to be of great importance....
Published: 10/28/2024   |   Inventor(s): Benjamin Miller, Brian Mcnaughton, Peter Gareiss, Joseph Wedekind
Keywords(s): AIDS, HIV, Small Molecule, Therapy
Category(s): Therapeutic
Novel, Synthetic Peptides that Inhibit the Formation of Tight Junctions
Background Current methods of vaccination primarily rely on intramuscular, subcutaneous, and intradermal injection of antigens. These vaccination routes, while effective, require medical personnel to deliver, generate biohazards (sharps) requiring costly disposal, and cause patients pain and anxiety. This has fueled research efforts to identify “needle-free”...
Published: 5/7/2024   |   Inventor(s): Benjamin Miller, Lisa Beck, Matthew Brewer
Keywords(s):  
Category(s): Therapeutic
Carbohydrate-targeted Therapeutic Agents, Diagnostics, and Sensors
Applications:Carbohydrates represent a particularly enticing and important challenge to the organic chemist interested in molecular recognition. In addition to their role in addressing the fundamental problem of understanding binding and selectivity, novel carbohydrate receptors have significant potential as tools in the rapidly evolving field of glycomics,...
Published: 5/7/2024   |   Inventor(s): Benjamin Miller, Prakash Palde, Peter Gareiss
Keywords(s): Research Tool
Category(s): Research Tools
Modulating Melanin Expression
Compounds which can induce melanin expression to aid in certain clinical indications or for cosmetic purposes.Problem Solved by This TechnologyMelanin is important for disease prevention, because it absorbs ultraviolet light in the UVB and UVA spectrum. This protects keratinocytes from the mutagenic effects of sunlight. In addition, melanin has a social...
Published: 5/7/2024   |   Inventor(s): Benjamin Miller, Brian Mcnaughton, Peter Gareiss, Glynis Scott
Keywords(s): Cancer, Dermatology, Oncology, Small Molecule, Therapy
Category(s): Therapeutic