Search Results - annalee+nguyen

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Monoclonal antibodies for the conserved feature of the coronavirus spike protein
The invention describes monoclonal antibodies targeting conserved epitopes on the S2 domain of coronavirus spike proteins, potentially useful for preventing or treating infections by inhibiting viral entry. These antibodies could aid in therapeutic formulations against coronaviruses like SARS-CoV-2, SARS-CoV, and MERS-CoV. Background The emergence...
Published: 10/16/2024   |   Inventor(s): Jennifer Maynard, Yimin Huang, Annalee Nguyen, Ching-Lin Hsieh, Jason McLellan, Eduardo Padlan
Keywords(s):  
Category(s): Life sciences > Immunology, Life sciences > Therapeutics > Vaccines
Innovative pH-selective antibody engineering for cancer therapy
Background Antibody-based cancer therapies have demonstrated impressive specificity but can lead to adverse effects by targeting antigens present on healthy cells. The acidic tumor microenvironment presents an opportunity for the development of anti­bodies with heightened tumor specificity through pH-dependent binding interactions. Technology...
Published: 5/3/2024   |   Inventor(s): Jennifer Maynard, Yutong Liu, Annalee Nguyen
Keywords(s):  
Category(s): Life sciences > Immunology
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit Endospores
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit EndosporesResearchers at Augusta University have invented skin-friendly compositions and methods for killing, inactivating, or otherwise reducing the bacterial endospores by using an effective amount of the green tea EGCG or its derivatives. EGCG research shows clear application for a hand sanitizer...
Published: 4/21/2023   |   Inventor(s): Stephen Hsu, Lee Lee, Tin-Chun Chu
Keywords(s):  
Category(s): Therapeutics
Ultrasound device and therapeutic methods
PAGE TITLE Overview PAGE SUMMARY The treatment of chronic wounds, including diabetic, venous, and decubitus ulcers has an annual cost of over $25 billion in the US alone. Over 2 million patients are treated for venous ulcers annually, contributing nearly $1 billion dollars toward that cost. Treatments for venous ulcers and their effectiveness...
Published: 6/24/2023   |   Inventor(s): Peter Lewin, Elisabeth Papazoglou, Youhan Sunny, Christopher Bawiec, An Nguyen, Joshua Samuels, Leonid Zubkov
Keywords(s):  
Category(s): Medical Devices & Diagnostics, Pharmaceuticals & Therapeutics, Medical Devices & Diagnostics > MDD: Therapeutic Devices, Pharmaceuticals & Therapeutics > Pharma: Drug Delivery