Search Results - an+nguyen

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One-Step Controlled Synthesis of Size Tunable Toroidal Gold Particles Using Green Chemistry
This invention is a method to control the size and shape of nanoparticles. It is a one-step synthesis process capable of tuning gold nanoparticles from 350nm to 1.7 microns using a process that has significantly reduced preparation time; it reduces hours for multi-step fabrication to 30-45 minutes. These synthesized toroidal particles exhibit surface...
Published: 6/27/2025   |   Inventor(s): Tsu-Te Su, Phuong Diem Nguyen, Xuanru Zhang
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Electronics, Technology Classifications > Materials > Nanomaterials
CBLs as a biomarker of and target to treat systemic lupus erythematosus (SLE)
SLE DIAGNOSTIC TOOL CBL protein levels used as a molecular diagnostic marker to diagnose and assess severity of Systemic Lupus Erythematosus (SLE) Systemic Lupus Erythematosus patient (photo: NCRD) UNMET NEED Systemic Lupus Erythematosus (SLE) is an autoimmune disease, especially prevalent in women, and without curative treatment. In addition,...
Published: 7/7/2025   |   Inventor(s): Xin Li, Zhe-Xiong Lian, Hua Gu
Keywords(s): Innovation
Category(s): Applications > Soins et santé > Diagnostic, English Applications > Health and care > Diagnostic-ENG, Secteurs > Sciences de la vie, Sectors > Life sciences, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sustainable Development Goals > Goal 03: Good Health and Well-Being
Lab on a 3D Printer (Case No. 2025-094)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel device capable of performing automated liquid handling to a great degree of precision on a miniaturized scale and with customizable features equipped for any laboratory task. Background: Automated liquid handling is essential in pharmaceutical and biotechnology research...
Published: 7/2/2025   |   Inventor(s): Dino Di Carlo, Shun Ye, Zixin Guan, Artem Goncharov, Vivek Rajasenan, Charlotte Rose McDonough, Tristan Lovely
Keywords(s): 3D biofabrication, 3D Printing, Automation, bioimaging, biomanufacturing, Biomaterial 3D Printing, Biomonitoring, Biosensor, Biotechnology, Drug Discovery, fluid mechanics, graphical user interface, Liquid tracking, mechanical durability, Robotic liquid handling
Category(s): Life Science Research Tools, Medical Devices, Diagnostic Markers, Life Science Research Tools > Lab Equipment, Mechanical
Novel Antibiotic Inhibiting Elongation Factor Complex in Gram-Positive Bacteria
​ Invention Summary: Antibiotic resistance remains a global health challenge with millions of related deaths each year. Gram-positive bacterial infections, like those caused by Staphylococcus aureus, are likely to acquire and develop resistance to clinically available antibiotics. Therefore, it is crucial to identify and develop novel antibiotics...
Published: 6/5/2025   |   Inventor(s): Wlodek Mandecki, Emanuel Goldman, Maxim Chudaev, Mark Henderson, Juan Marugan, Wenjuan Ye, Kenneth Wilson, Dane Parker
Keywords(s): Antibacterial, Small molecules
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease, Technology Classifications > Therapeutics
SAMURI-Self-Administered Multiplex Universal Radiation Indicator
SAMURI is an innovative point-of-care biodosimetry screening kit designed to detect and measure specific proteins and transcripts within leukocytes that serve as radiation biomarkers. The kit utilizes a vertical flow immunoassay, integrating all the necessary components for sample collection, preparation, bioassay, detection, automated data analysis,...
Published: 6/4/2025   |   Inventor(s): Frederic Zenhausern, Jerome Lacombe, Sally Amundson, Jian Gu, Helen Turner, Igor Shuryak, Michael Price
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
First in class Small Molecule Agonists of the mammalian Relaxin family receptor 1 (RXFP1) and use in treatment of cancer, fibrotic, and vascular disorders (HHS Ref No. E-145-2024-0-US-02)
It is well documented in literature that activation of RXFP1 by relaxin induces: 1) up-regulation of the endothelin system which leads to vasodilation; 2) extracellular matrix remodeling through regulation of collagen deposition, cell invasiveness, proliferation, and overall tissue homeostasis; 3) a moderation of inflammation by reducing levels of inflammatory...
Published: 5/30/2025   |   Inventor(s): Juan Marugan, Mark Henderson, Kenneth Wilson, Wenwei Huang, Wenjuan Ye, Noel Southall, Jiankang Jiang, Khalida Shamim, Bing Li, Alexander Agoulnik, Abhijeet Kapoor, Joshua Hutcheson, Ana Cabrera, Irina Agoulnik
Keywords(s):  
Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Pulmonology, TherapeuticArea > Dermatology, TherapeuticArea > Reproductive Health, TherapeuticArea > Geriatrics
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025   |   Inventor(s): Stephen Liggett, Donghwa Kim, Yu Chen, Jesper Madsen, Steven An
Keywords(s): Pharmaceuticals, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals
Development of an Innovative AI-Enhanced Music-Based Magnetic Respiratory Therapy System
Advantages Uses magnetic sensors to monitor breathing without wires or chest straps AI adapts music in real time to regulate and stabilize respiration Designed for stress relief, respiratory therapy, and sleep quality improvement Comfortable, low-cost, and easy to use for home or clinical settings Summary Patients with respiratory issues whether...
Published: 5/20/2025   |   Inventor(s): Manh-Huong Phan, Dang Nguyen, Kee Young Hwang
Keywords(s): Therapeutics
Category(s): Technology Classifications > Medical > Therapeutics
Auto Hoist Stabilization System with Wireless Sync
THE CHALLENGE Modern helicopter rescue operations require hoist operations that are safe, fast, and stable—particularly when suspended payloads swing dangerously due to wind, rotor wash, or sudden movements. These swings not only pose serious safety risks but also slow down mission times and increase stress on crews. Existing systems often rely...
Published: 6/25/2025   |   Inventor(s): David Reineke, Kyle Nguyen, Luyi Tang, Walter Lacarbonara, Mary Lanzerotti, Rui Peng
Keywords(s):  
Category(s): Technology Classifications > Engineering, Technology Classifications > Architecture/Building, Technology Classifications > Mining and Recycling, Technology Classifications > Electronics
MDCare: AI-Based Real-Time Surgical Blood Loss Quantification System
Advantages Real-time and continuous blood loss estimation Automated and objective, minimizing human error Enhances surgical decision-making Seamlessly integrates into clinical workflows Mobile alerts for timely, remote monitoring Summary Inaccurate blood loss estimation during surgery remains a critical challenge, with traditional visual and...
Published: 7/9/2025   |   Inventor(s): Phat Huynh, Dang Nguyen, Trung Le, Aaron Muncey, Heath Rutledge-Jukes, Pallavi Jonnalagadda, Sammer Marzouk, Tram Le
Keywords(s): Artificial Intelligence, Medical Diagnostics, Sensors
Category(s): Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Medical Sensors, Technology Classifications > Medical > Surgery, Technology Classifications > Data/AI > D/AI Imaging
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