Search Results - an+nguyen

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A New Method for Dual Detection of Magnetic and Dielectric Signals from Core/Shell Nanoparticles for Advanced Biodetection and Diagnostics
Advantages Simultaneously detects magnetic and dielectric signals from core/shell nanoparticles with high sensitivity. Provides rapid, real-time biodetection in microfluidic systems using minimal sample volumes. Accurately differentiates healthy and cancer cells through enhanced signal responsiveness. Easily integrates into scalable biomedical...
Published: 12/1/2025   |   Inventor(s): Manh-Huong Phan, Kee Young Hwang, T. Lee, Minh Nguyen, Supawitch Hoijang, Dakota Brown
Keywords(s): Biomarker, Nanotechnology, Sensors
Category(s): Technology Classifications > Electronics > Nanotechnology
Method and Apparatus for Improving the Signal-To-Noise Ratio in Multi-Dimensional Magnetic Resonance Imaging Data (Case No. 2025-204)
Summary: UCLA researchers have developed a software-based denoising method that makes cardiac MRI images clearer and more reliable, enabling more accurate heart function measurements without requiring longer scan times. Background: Cardiac MRI is a powerful imaging tool for assessing heart health because it can provide detailed pictures of how the...
Published: 11/13/2025   |   Inventor(s): Xiaodong Zhong, Shu-Fu Shih, Holden Wu, Kim-Lien Nguyen
Keywords(s): 2D ultrasound imaging, 3D tissue imaging, 3D ultrasound imaging, AI-guided medical imaging, AI-guided medical intervention, bioimaging, Biologic Medical Product, Biomedical Engineering, Cardiac Magnetic Resonance Imaging, Image Analysis, Imaging, Magnetic Resonance Imaging, Magnetic Resonance Imaging Carotid Artery Stenosis, Magnetic Resonance Imaging Hypoxia (Medical), Magnetic Resonance Imaging Medical Physics, Magnetic Resonance Imaging Microangiopathy, Magnetic Resonance Imaging Pathology, Magnetic Resonance Imaging Spin Polarization, Magnetic Resonance Imaging Unmanned Aerial Vehicle, Medical artificial intelligence (AI), Medical Device, medical device cardiac monitoring, Medical Devices and Materials, Medical diagnostics, Medical Imaging
Category(s): Medical Devices > Cardiac, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Software & Algorithms > Image Processing, Software & Algorithms
Multiomic Approaches to Pediatric Inflammatory Bowel Disease
Invention Description Pediatric Inflammatory Bowel Disease (IBD), encompassing Crohn’s Disease and Ulcerative Colitis, presents significant clinical challenges due to its complex and heterogeneous nature, often leading to lifelong health complications. Current diagnostic and therapeutic strategies are limited by an incomplete understanding of...
Published: 11/12/2025   |   Inventor(s): Todd Sandrin, Peter Jurutka, Haiwei Gu, Brad Pasternak
Keywords(s):  
Category(s): Applied Technologies, Diagnostic Assays/Devices, Life Science (All LS Techs), Pharmaceuticals, Proteomic Assays/Reagents/Tools
Scalable Magneto-Optical Trap and Gravimeter
​ (a) Side-view schematic of dual-MOT. (b) Mounted mirrors. (c) MOT mirror. (d) Incident laser beam. (e) Passing through laser beam after the 1st mirror. (f) Passing-through laser beam after the 2nd mirror. Invention Summary: Cold-atom-sensors such as atomic gravimeters have been used in geological surveys and navigation. The complexities involved...
Published: 10/31/2025   |   Inventor(s): Xuejian Wu, Timothy Nguyen, Mariam Mchedlidze
Keywords(s):  
Category(s): Technology Classifications > Sensors, Technology Classifications > Physical Sciences & Engineering
Scalable Magneto-Optical Trap and Gravimeter
​ (a) Side-view schematic of dual-MOT. (b) Mounted mirrors. (c) MOT mirror. (d) Incident laser beam. (e) Passing through laser beam after the 1st mirror. (f) Passing-through laser beam after the 2nd mirror. Invention Summary: Cold-atom-sensors such as atomic gravimeters have been used in geological surveys and navigation. The complexities involved...
Published: 10/31/2025   |   Inventor(s): Xuejian Wu, Timothy Nguyen, Mariam Mchedlidze, Guanghui Su
Keywords(s): Machines & Instruments
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Sensors
A Potent HIV Treatment with Low Toxicity
A small-molecule class that binds to HIV particles to improve immune response and block viral entry into cells. Problem: 37 million people worldwide currently live with HIV and an estimated 2-3 million new infections occur annually. While antiretroviral therapies do exist for those with the disease, therapy interruption leads to the re-emergence of...
Published: 11/11/2025   |   Inventor(s): Amos Smith, Xuchen Zhao, Tyler Higgins, Andres Finzi, Shilei Ding, Daniel Lee, Marzena Pazgier, Dung Nguyen, William Tolbert
Keywords(s): Drug Target, HIV/AIDS, Small Molecule, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics
Tumor-pH–Triggered Doxorubicin Prodrug with On-Demand Shelf-Stable Precursor
This invention introduces a small-molecule doxorubicin prodrug that remains inert in blood and rapidly activates in the mildly acidic tumor microenvironment. Featuring a shelf-stable maleimide pre-prodrug that converts on demand to the ultra-acid-labile DMA form, it enables targeted chemotherapy with improved selectivity, scalable synthesis, and reduced...
Published: 11/12/2025   |   Inventor(s): Ming An, Lan Yao, Vladyslav Nazarenko
Keywords(s): Technologies
Category(s): Campus > Binghamton University
Efficient Genome Editing Tool Using CODE Systems for Precise Modifications
Complements Existing Prime Editors to Expand Toolbox for Genome Manipulations This precision-driven genome editing tool uses chimeric oligonucleotide-directed editing (CODE) to replace, insert, or delete specific genes with exceptional accuracy. The genome editing market, valued at nearly $10 billion in 2024 and anticipated to grow to $25 billion by...
Published: 10/9/2025   |   Inventor(s): Piyush Jain, Noah Rakestraw, Briana Pizzano, Cameron Myhrvold, Long Nguyen
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Microfluidic Device Design for Point-of-Care Devices
Implementing liquid-based assays, such as PCR and LAMP, is difficult in POC microfluidic devices, due to bubble formation. To mitigate this, auxiliary metering systems or actuators are required to regulate consistent flow rates. This can make the microfluidic device more complicated to operate, increases cost, and limits rapid prototyping, ultimately...
Published: 9/29/2025   |   Inventor(s): Vi Nguyen, Jennifer Blain Christen
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Medical Diagnostics/Sensors, Genomic Assays/Reagents/Tools
CBLs as a biomarker of and target to treat systemic lupus erythematosus (SLE)
SLE DIAGNOSTIC TOOL CBL protein levels used as a molecular diagnostic marker to diagnose and assess severity of Systemic Lupus Erythematosus (SLE) Systemic Lupus Erythematosus patient (photo: NCRD) UNMET NEED Systemic Lupus Erythematosus (SLE) is an autoimmune disease, especially prevalent in women, and without curative treatment. In addition,...
Published: 12/3/2025   |   Inventor(s): Xin Li, Zhe-Xiong Lian, Hua Gu
Keywords(s): Innovation
Category(s): Applications > Soins et santé > Diagnostic, English Applications > Health and care > Diagnostic-ENG, Secteurs > Sciences de la vie, Sectors > Life sciences, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sustainable Development Goals > Goal 03: Good Health and Well-Being
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