Search Results - an+nguyen

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Method for Non-invasive Assessment of Pressure and Cardiac Efficiency (Case No. 2024-258)
Summary: Researchers in the Department of Medicine and Radiological Sciences at UCLA have developed a novel computational model for estimating ventricular mechanical efficiency using routine clinical exam practices. Background: Congenital heart disease (CHD) involves complex heart defects that make it harder for the heart to pump blood effectively....
Published: 4/4/2025   |   Inventor(s): Kim-Lien Nguyen, Sanjib Gurung, John Finn
Keywords(s): acute myocardial infarction, Blood Pressure, Catheterization, heart disease mitigation, heart failure, heart support, hemodynamic monitoring, ventricular system
Category(s): Therapeutics > Cardiovascular, Therapeutics > Radiology, Medical Devices > Cardiac, Medical Devices > Monitoring And Recording Systems, Therapeutics > Inflammation And Inflammatory Diseases, Medical Devices > Medical Imaging, Software & Algorithms > Bioinformatics
Efficient Decoding Algorithms for Reed-Muller Codes, Recursive Projection-Aggregation and List-Decoding
Efficient Decoding Algorithms for Reed-Muller Codes, Recursive Projection-Aggregation and List-Decoding Princeton Docket # 19-3543-1 Reed-Muller (RM) codes are among the oldest families of error-correcting codes. Compared to polar codes, RM codes have the advantage of having a simple and universal code construction, though RM codes do not yet possess...
Published: 4/10/2025   |   Inventor(s): Min Ye, Emmanuel Abbe
Keywords(s):  
Category(s): Computer Science and Information Technology
An Adaptive Approach for Synthetic Microvascular Network Generation (Case No. 2024-259)
Summary: UCLA researchers from the Department of Medicine have developed a method for synthetic microvascular network generation for improved coronary disease monitoring. Background: Synthetic microvascular network modeling can be used in diagnosing and managing microvascular diseases such as coronary microvascular disease (CMD). CMD is traditionally...
Published: 4/4/2025   |   Inventor(s): Kim-Lien Nguyen, Mostafa Mahmoudi, Amirhosseini Arzani
Keywords(s):  
Category(s): Medical Devices, Medical Devices > Cardiac, Medical Devices > Hospital Systems, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Software & Algorithms, Software & Algorithms > Digital Health
3D Printed Glass Optical Elements with Controllable Local Transmission and Manufacturing Process
This invention is a method for fabricating complex 3D printed glass microstructures with controllable local transparency, targeting applications such as optical lens design and advanced optical components. It uses polymeric silsesquioxane (PSQ) and two-photon polymerization (TPP) to tune transparency levels by manipulating parameters like laser power,...
Published: 1/21/2025   |   Inventor(s): Rongguang Liang, Zhihan Hong, Piaoran Ye, Douglas Loy
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Materials & Fabrication, Technology Classifications > Imaging & Optics > Lens & System Design
Antibacterial Coagulating Gel Spray
Blood loss and infections are a major cause of concern and death for traumatic injuries and wounds. It is estimated that blood loss accounts for more than 35% of all prehospital deaths in trauma patients. Thus, it is imperative that bleeding is stopped quickly and at the point of care. While there are many products to staunch bleeding, including gauze...
Published: 3/11/2025   |   Inventor(s): Emily Byrne, Grace Billingsley, Tran Nguyen, Alfonso Gomez-De Leon, Oscar Voeller, Sarah Stabenfeldt, Jessica Weaver
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Biomaterials, Life Science (All LS Techs), Medical Devices
Selective Modulators of Ah-R to Treat Cancer
Synergistic compositions and method of using modulators of Ah-R activity and synergistic compounds to treat cancer Background Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor. When activated by the binding of a wide range of both endogenous and exogenous small molecules, AhR signaling influences cellular outcomes in different...
Published: 1/8/2025   |   Inventor(s): Siva Kolluri, Bach Nguyen, Daniel Elson
Keywords(s):  
Category(s): Therapeutics
A Dynamic and Adaptive Approach for Resolving Motion (Case No. 2024-250)
Summary: UCLA researchers in the Department of Radiology have developed a novel method to capture time-varying and irregular cardiac motion, producing high-precision, high-quality cine images. Background: Cine MRI is a specialized imaging technique that captures motion through a series of images, often used to evaluate cardiac function and morphology....
Published: 3/24/2025   |   Inventor(s): Zhengyang Ming, Dan Ruan, Anthony Christodoulou, Kim-Lien Nguyen
Keywords(s): arrhythmia, Biomonitoring, Cardiac Magnetic Resonance Imaging, cardiovascular diseases, cardiovascular monitoring, Image Resolution, Imaging, Magnetic Resonance Imaging, Medical Device, medical device cardiac monitoring, Medical Imaging, Monitoring And Recording Systems, MRI, non-invasive cardiac monitoring, optimization
Category(s): Medical Devices, Medical Devices > Cardiac, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Medical Devices > Monitoring And Recording Systems
Enhanced S10-3 Cell Line for Advanced Hepatitis E Virus Research and Therapeutic Development
The Huh-7 cell line underwent a detailed sub-cloning process to enhance its effectiveness for Hepatitis E Virus (HEV) infection studies. This involved diluting and culturing cells in 96-well plates until confluent monolayers formed, followed by selection and expansion of the most suitable cells. The sub-clone S10-3, derived from this process, was identified...
Published: 12/10/2024   |   Inventor(s): Suzanne Emerson, Hanh Nguyen, Udana Torian
Keywords(s):  
Category(s): Application > Research Materials, ResearchProducts, ResearchProducts > Human Cell Lines, TherapeuticArea > Infectious Disease
Enhanced fluorescence via DNA aptamer optimization
This invention improves the fluorescence of DNA-based aptamers by sub­stituting the original fluorophore with TO1-biotin and identifying a critical mutation that further enhances fluorescence. Background Fluorogenic DNA aptamers (FAPs) are a crucial tool in molecular biology, particularly for applications like live-cell imaging and highly specific...
Published: 12/6/2024   |   Inventor(s): Hsin-Chih (Tim) Yeh, Yuan-I Chen, Yu-An Kuo, Yujie He, Trung Nguyen, Soonwoo Hong, Anh-Thu Nguyen, Sohyun Kim, Saeed Seifi
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform
Enhanced fluorescence via DNA aptamer optimization
This invention improves the fluorescence of DNA-based aptamers by sub­stituting the original fluorophore with TO1-biotin and identifying a critical mutation that further enhances fluorescence. Background Fluorogenic DNA aptamers (FAPs) are a crucial tool in molecular biology, particularly for applications like live-cell imaging and highly specific...
Published: 12/6/2024   |   Inventor(s): Hsin-Chih (Tim) Yeh, Yuan-I Chen, Yu-An Kuo, Yujie He, Trung Nguyen, Soonwoo Hong, Anh-Thu Nguyen, Sohyun Kim, Saeed Seifi
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform
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