Search Results - ellen+wagner

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Engineered T-cell receptor platforms for targeted detection and treatment of cytomegalovirus-infected cells
This technology uses highly engineered T-cell receptors to precisely detect and target cytomegalovirus-infected cells, offering improved therapies and diagnostics by enhancing binding strength, stability, and resistance to viral immune evasion. Background Cytomegalovirus (CMV) is a widespread herpesvirus that poses significant health risks, particularly...
Published: 2/26/2026   |   Inventor(s): Jennifer Maynard, Ellen Wagner, Ahlam Qerqez, Annalee Nguyen
Keywords(s):  
Category(s): Life sciences > Immunology, Life sciences > Therapeutics
Dual-target defense: bispecific antibodies revolutionize pertussis toxin neutralization
­Bispecific antibodies target two epitopes on the pertussis toxin protein, enhancing toxin neutralization. Engineered using “knobs-into-holes” tech­nology, they form stable heterodimers, offering similar efficacy to antibody mixtures but with streamlined manufacturing and regulatory benefits. Background Pertussis, or whooping cough,...
Published: 1/13/2026   |   Inventor(s): Jennifer Maynard, Ellen Wagner
Keywords(s):  
Category(s): Life sciences > Therapeutics > Gene therapy, Life sciences > Immunology