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Dual-target defense: bispecific antibodies revolutionize pertussis toxin neutralization
­Bispecific antibodies target two epitopes on the pertussis toxin protein, enhancing toxin neutralization. Engineered using “knobs-into-holes” tech­nology, they form stable heterodimers, offering similar efficacy to antibody mixtures but with streamlined manufacturing and regulatory benefits. Background Pertussis, or whooping cough,...
Published: 9/6/2024   |   Inventor(s): Jennifer Maynard, Ellen Wagner
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Category(s): Life sciences > Therapeutics > Gene therapy, Life sciences > Immunology