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Search Results - ahlam+qerqez
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Dual-target antibody toolkit for overcoming resistance in anti-angiogenic cancer therapy
Background Angiogenesis is a fundamental process in cancer progression, enabling tumors to grow and metastasize by forming new blood vessels. Vascular endothelial growth factor A (VEGFA) is a central driver of this process and a primary target for existing anti-angiogenic therapies. However, clinical resistance often develops through the compensatory...
Published: 1/27/2026
|
Inventor(s):
Jennifer Maynard
,
Samuel Blackman
,
Ahlam Qerqez
,
Nicole Johnson
,
Annalee Nguyen
,
Alison Lee
Keywords(s):
Category(s):
Life sciences > Immunology
,
Life sciences > Research tools > Reagent
Engineered antibodies for enhanced immune response
Recombinant antibodies with engineered human IgG1 Fc domains have been developed to resist viral Fc receptor capture, enhancing immune targeting of virus-infected cells. These antibodies maintain normal host receptor affinity, potentially improving therapeutic outcomes against HCMV and related viruses. Background Human cytomegalovirus (HCMV) infection...
Published: 1/13/2026
|
Inventor(s):
Jennifer Maynard
,
Ahlam Qerqez
,
Alison Lee
,
Sumit Pareek
Keywords(s):
Category(s):
Life sciences > Immunology