Search Results - ahlam+qerqez

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Engineered T-cell receptor platforms for targeted detection and treatment of cytomegalovirus-infected cells
This technology uses highly engineered T-cell receptors to precisely detect and target cytomegalovirus-infected cells, offering improved therapies and diagnostics by enhancing binding strength, stability, and resistance to viral immune evasion. Background Cytomegalovirus (CMV) is a widespread herpesvirus that poses significant health risks, particularly...
Published: 2/26/2026   |   Updated: 2/26/2026   |   Inventor(s): Jennifer Maynard, Ellen Wagner, Ahlam Qerqez, Annalee Nguyen
Keywords(s):  
Category(s): Life sciences > Immunology, Life sciences > Therapeutics
Dual-target antibody toolkit for overcoming resistance in anti-angiogenic cancer therapy
Background Angiogenesis is a fundamental process in cancer progression, enabling tumors to grow and metastasize by forming new blood vessels. Vascular endothelial growth factor A (VEGFA) is a central driver of this process and a primary target for existing anti-angiogenic therapies. However, clinical resistance often develops through the compensatory...
Published: 1/27/2026   |   Updated: 1/27/2026   |   Inventor(s): Jennifer Maynard, Samuel Blackman, Ahlam Qerqez, Nicole Johnson, Annalee Nguyen, Alison Lee
Keywords(s):  
Category(s): Life sciences > Immunology, Life sciences > Research tools > Reagent
Engineered antibodies for enhanced immune response
Recombinant antibodies with engineered human IgG1 Fc domains have been developed to resist viral Fc receptor capture, enhancing immune targeting of virus-infected cells. These antibodies maintain normal host receptor affinity, potentially improving therapeutic outcomes against HCMV and related viruses. Background Human cytomegalovirus (HCMV) infection...
Published: 1/13/2026   |   Updated: 10/21/2024   |   Inventor(s): Jennifer Maynard, Ahlam Qerqez, Alison Lee, Sumit Pareek
Keywords(s):  
Category(s): Life sciences > Immunology