Search Results - optical+imaging

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Coumarin Luciferins and Mutant Luciferases for Bioluminescence Imaging
Abstract: Bioluminescence imaging with luciferin-luciferase pairs is a well-established technique for tracking cells and other biological features in animal models. Bioluminescent is a chemical process which does not require an external input for excitation. Bioluminescent imaging is often limited to monitoring single processes in vivo due to the lack...
Published: 4/8/2024   |   Inventor(s): Martin Schnermann, Donald Caldwell, Jennifer Prescher, Zi Wei Yao, Anna Love
Keywords(s): CouLuc, Luciferases, Luciferins, Near-infrared, NIR, Optical Imaging, Schnermann
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Application > Therapeutics
­METHODS AND SYSTEM FOR SPECTRAL IMAGING OF DENSITY, ANISTROPY, AND ORIENTATION
­METHODS AND SYSTEM FOR SPECTRAL IMAGING OF DENSITY, ANISTROPY, AND ORIENTATION Researchers at the Chan Zuckerberg Biohub have developed an imaging module and computational algorithms for high-speed spectral quantitative imaging of density and anisotropy in fluorescence and label-free contrasts. Microscopy is central to biological research and...
Published: 3/17/2023   |   Inventor(s): Shalin Mehta, Ivan Ivanov, Li-Hao Yeh
Keywords(s): Anisotropy, Biomolecules, Density, Microscopy, Optical Imaging, Polarization
Category(s): Technology Classifications > Engineering
­METHOD AND SYSTEM FOR QUANTITATIVE THREE-DIMENSIONAL MEASUREMENT OF DENSITY, ANISOTROPY, AND ORIENTATION WITHOUT LABEL
­METHOD AND SYSTEM FOR QUANTITATIVE THREE-DIMENSIONAL MEASUREMENT OF DENSITY, ANISOTROPY, AND ORIENTATION WITHOUT LABEL Researchers at the Chan Zuckerberg Biohub have developed a label-free computational imaging method for measuring optical properties of a specimen. Biological architecture is intrinsically tensorial. The permittivity tensor (PT)...
Published: 3/17/2023   |   Inventor(s): Shalin Mehta, Ivan Ivanov, Li-Hao Yeh
Keywords(s): Anisotropy, Biomolecules, Density, Microscopy, Optical Imaging, Polarization
Category(s): Technology Classifications > Engineering
Full-Angle OCT Probe for 360-Degree View in Endoscopic Scanning
Broadens Scanning Angle to Capture Full Circumferential Optical Scan in One Insertion of the Probe, Reducing Patient DiscomfortThis optical coherence tomography (OCT) probe uses an electrothermal microelectromechanical systems (MEMS) mirror kept in liquid to increase the optical scan range and shock resistance of OCT probes. OCT is a medical imaging...
Published: 6/27/2021   |   Inventor(s): Huikai Xie, Xiaoyang Zhang, Sanjeev Koppal, Can Duan, Liang Zhou
Keywords(s): Endoscopy, MEMS Mirror, Optical Coherence Tomography (OCT), Optical Imaging
Category(s): Technology Classifications > Engineering > Instrumentation-Sensors-Photonics, Technology Classifications > Medical Devices > Others