Search Results - andrew+tsourkas

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Dye-Loaded Micelles for Direct Visualization of Colorectal Cancer
A tissue-selective, biocompatible contrast agent enables the visual identification of tumors and tumor margins during procedures Problem: Dye-based chromoendoscopy (DBC) helps endoscopists visualize colorectal mucosa and identify inflammatory polyps that could progress toward colorectal cancer in patients with inflammatory bowel disease (IBD). However,...
Published: 8/2/2024   |   Inventor(s): Andrew Tsourkas, Ahmad Amirshaghaghi, Zhiliang Cheng, Karthik Sundaram, Yiran Tian
Keywords(s): Bioengineering, Imaging Agents, Nanotechnology, Oncology, Surgery
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Imaging, Technology Classifications > Materials
Coated Metallic Nanoclusters without Carrier Molecule
Nanocluster agents that enable imaging through cyanine dyes and/or photosensitizers without the need for additional carrier molecules. Problem: There is a need for visual inspection and feedback before and during surgery for removing tumors and cancerous cells from surrounding healthy tissue. Better visualization can lead to better prognosis because...
Published: 10/16/2023   |   Inventor(s): Andrew Tsourkas, Jayesh Thawani, Ahmad Amirshaghaghi, Lesan Yan, Zhiliang Cheng
Keywords(s): Antibody, Cell Therapy
Category(s): Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics, Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Imaging, Technology Classifications > Materials
Optical probes for real-time nucleic acid detection and gene expression analysis in living cells
Fluorescent ratiometric bimolecular beacons with spatiotemporal resolution Problem: Common gene expression analysis methods, including polymerase chain reaction, microarrays, and in situ hybridization rely on fixed or lysed cells, hindering their ability to provide spatiotemporal information. This led to the development of optical probes that enable...
Published: 10/16/2023   |   Inventor(s): Andrew Tsourkas
Keywords(s): Optics & Photonics 
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics, Technology Classifications > Imaging