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LNP-Enabled Intracellular Delivery of Recombinant bioPROTACs
Recombinant fusion bioPROTACs are combined with cationic delivery agents and lipid formulations to enable cytosolic entry and on-demand intracellular degradation of target proteins. Tech Title: Technology: Technology: The core construct is a recombinant fusion protein comprising an E3 ubiquitin ligase domain, a small protein binding scaffold, and an...
Published: 6/9/2026   |   Updated: 5/29/2026   |   Inventor(s): Andrew Tsourkas, Alexander Chan
Keywords(s): Protein/Peptide (Non-Antibody), Soft Materials
Category(s): Technology Classifications > Therapeutics