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Random and Safe (RaS) Cache Architecture to Defeat Cache Timing Attacks

Random and Safe (RaS) Cache Architecture to Defeat Cache Timing Attacks Princeton Docket # 25-4192-1 Princeton University researchers have developed an innovative hardware solution known as Random and Safe (RaS) caches to address critical security vulnerabilities in modern computer systems. This technology significantly enhances security by effectively...

Published: 12/11/2024 | Inventor(s): Ruby Lee, Guangyuan Hu

Keywords(s):

Category(s): Mechanical/Electrical Engineering

Rare-Earth-Element Free Yellow Phosphors for White Light-Emitting Diodes

Yellow phosphor emits white light when excited with the 460 nm blue lighting. The blue LED (left half; top) when coated with dispersed yellow phosphor (right half; top) emits white light. Invention Summary: Despite their low energy consumption and higher efficiency, white light-emitting diodes made of blue chip coupled with yellow phosphor...

Published: 12/4/2024 | Inventor(s): Jing Li, Zhichao Hu, Qihan Gong

Keywords(s): Electronics, LEDs

Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Electronics/Semiconductor

S100A4 Monoclonal Antibody for Therapeutic and Diagnostic Use

Cancer metastasis are responsible for ~90% of cancer associated deaths. Recent studies suggest that immune cells play critical roles in promoting metastasis, especially myeloid cells from the bone marrow. UTHealth researchers, with researchers from The Methodist Hospital, observed a highly conserved expression of S100A4 in immune suppressive myeloid...

Published: 10/21/2024 | Inventor(s): Zhiqiang An, Ningyan Zhang

Keywords(s):

Category(s): Neurology/Neurosurgery, Oncology, Therapeutics

LILRB2 Monoclonal Antibody for Therapeutic and Diagnostic Uses of Neurodegenerative Diseases

Triggering Receptor Expressed on Myeloid cells 2 (TREM2) plays a key regulatory role in Alzheimer’s disease (AD) by controlling microglia activation and metabolic activities in brain tissues. TREM2 signaling inhibition is mediated by leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2). UTHealth inventors created and engineered...

Published: 10/21/2024 | Inventor(s): Zhiqiang An, Ningyan Zhang

Keywords(s):

Category(s): Neurology/Neurosurgery, Therapeutics

Oxynitidine Derivatives Useful as Inhibitors of Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) for Treating Cancer

Summary: The National Cancer Institute (NCI) is actively seeking potential licensees and/or co-development research collaboration partners interested in advancing oxynitidine derivatives as novel inhibitors of topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 (TDP1) for cancer treatment. These TOPI and TDP1 inhibitors, when administered...

Published: 9/18/2024 | Inventor(s): Yves Pommier, Lin-kun An, Keli Agama, Evgeny Kiselev, Azhar Ravji

Keywords(s): Benzophenanthridine Derivatives, Benzophenanthridinone, Camptothecin, Dihydrobenzophenanthridine, IRINOTECAN, Oxynitidine, Pommier, Tdp1, TOP1, Topoisomerase 1B, Topotecan, Tyrosyl-DNA Phosphodiesterase 1

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Therapeutics

Comprehensive and Individualized Menopause Care Delivery Protocol With Technological Decision Support Aid (Case No. 2024-193)

Summary: Researchers in the UCLA Department of Obstetrics and Gynecology have developed a new clinical decision support system for improved menopause care. Background: Each year, approximately 1.3 million women in the United States enter menopause. This is often accompanied by symptoms such as hot flashes, mood changes, and sleep issues. In addition,...

Published: 10/2/2024 | Inventor(s): Rajita Patil, Erica Oberman, Brittany Davis, Rhonda Voskuhl, Kathleen Van Dyk, Ravi Aysola, Louise Dixon De Silva, Karol Watson, Lua Jafari, Julie Bernthal, Rashmi Mullur, Albert Shieh, Elizabeth Ko, Katie Hu, Aashini Master, Kelly Mccann, Kelsey Collins, Katherine Unverferth, Tamara Grisales, Amy Rosenman, Andrea Rapkin

Keywords(s): clinical care methodology, clinical decision support, EHR, EHR integration, electronic health records (EHR), FemTech, femtech medical device, lab results analysis, medical bias reduction, Menopause, menopause management, patient questionnaire, period, personalized medicine, predictive analytics, specialist referral, women’s health

Category(s): Software & Algorithms, Software & Algorithms > Programs, Software & Algorithms > Digital Health, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices, Medical Devices > FemTech

New Drugs for the Prevention of Kidney Stones

In vivo efficacy study of an LH prodrug expressed as days CaOx crystals were detected in mouse urine/mouse/week Invention Summary: Hyperoxaluria is a condition characterized by excessive urinary excretion of oxalate. It can result from inherited genetic mutations, intestinal diseases, or a diet high in oxalate. This often leads to calcium...

Published: 11/20/2024 | Inventor(s): Longqin Hu, Yiling Wang

Keywords(s): Drug Discovery/Screening

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics

Bioinformatics-powered CRISPR-transposon systems for enhanced gene editing and horizontal gene transfer

CRISPR-associated transposons (CASTs) use nuclease-deficient CRISPR-Cas systems for RNA-guided gene insertion, enhancing the gene-editing toolkit by enabling precise DNA integration. Background CRISPR-associated transposons (CASTs) represent a significant advancement in gene-editing technology, originating from the fusion of CRISPR-Cas systems with...

Published: 8/8/2024 | Inventor(s): Ilya Finkelstein, James Rybarski, Kuang Hu, Alexis Hill, Claus Wilke

Keywords(s):

Category(s): Life sciences > Research tools > Reagent

Ultra-Fast, Continuous COVID-19 Inactivation and Outbreak Control by Flexible Spray-on Coating (Case No. 2021-247)

Intro Sentence: UCLA researchers from the Department of Mechanical and Aerospace Engineering have developed a novel antibacterial and antiviral spray-on coating. Background: Smart materials present an important method of protecting public health from emerging infectious diseases such as COVID-19, severe acute respiratory syndrome (SARS), avian...

Published: 7/19/2024 | Inventor(s): Yongjie Hu, Yuan Shi, Ying Cui

Keywords(s): antimicrobial coatings, antimicrobial materials, antiviral coatings, Antiviral Drug, antivirals, continuous antiviral function, environmental disease transmission, environmental transmission, light-to-heat conversion, Microbiology, pandemic control, photothermal materials, polypyrrole, safety protocols, solar irradiation, Viral Delivery Systems

Category(s): Energy & Environment, Chemical, Chemical > Coatings, Adhesives & Inks, Medical Devices, Medical Devices > Hospital Systems

Electrically Gated Solid-State Molecular Thermal Transistor (Case No. 2024-099)

Summary: UCLA researchers have introduced a solid-state thermal transistor that achieves groundbreaking performance and facilitates improved heat flow manipulation. Background: The forefront of thermal management is marked by the exploration of molecular thermal transistors, driven by the quest for more efficient electronic devices. Researchers are...

Published: 10/23/2024 | Inventor(s): Yongjie Hu, Paul Weiss, Man Li

Keywords(s): ; self-assembled molecule, Composite Material, Doping (Semiconductor), Elastic Modulus Thermal Grease, Electronics & Semiconductors, field-effect transistors (FETs), Functional Materials, heat control, heat controlling devices, infrared thermal imaging, Microelectronics Semiconductor Device Fabrication, molecular design, molecular engineering, molecular junction, Nanomaterials, Optoelectronic materials, Optomechanical Thermal Imaging Transducer, organic field effect transistors, Organic Semiconductor, phase change materials, Rechargeable Battery Thermal Conductivity, self-assembled molecule, Semiconductor, semiconductor chip foundries, Semiconductor Device, Semiconductor Device Fabrication, Semiconductor Ohmic Contact, Semiconductor Risk Assessment, Semiconductor Sapphire, Semiconductors, solid-state thermal transistor, strength-thermal stability, switching reversibility, thermal circuit, thermal compression bonding, thermal conductance, Thermal Energy Storage, thermal fusion, thermal imaging, thermal management systems, thermal stability, thermal switching speed, thermal switching speeds, thermal transistor, Thin-Film Transistor, Transistor, transistors, zzsemiconducting materials

Category(s): Electrical, Electrical > Electronics & Semiconductors, Energy & Environment, Energy & Environment > Energy Generation, Energy & Environment > Energy Storage, Energy & Environment > Energy Transmission, Energy & Environment > Thermal, Electrical > Instrumentation, Materials, Materials > Nanotechnology

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