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Peptide ligands for affinity capture of mRNA and methods of discovery thereof
RPI ID: 2022-060-301 Innovation Summary: This technology describes peptide ligands engineered for the affinity capture of nucleic acids, including DNA and RNA, in solution. These ligands are designed to bind selectively to nucleic acid targets, enabling efficient isolation and purification. The method includes synthesis and screening of peptide sequences...
Published: 3/10/2026
|
Inventor(s):
Pankaj Karande
,
Mengyang Hu
,
Georges Belfort
Keywords(s):
mRNA
,
Peptides
,
Purification
,
Vaccine
Category(s):
Biotechnology and the Life Sciences
A Selenium Buffer Method for Making Van Der Waals Contact on CDTE Wafers With High Surface Roughness (Case No. 2025-173)
Summary: UCLA researchers in the Department of Chemistry & Biochemistry have developed a novel method for implementation of Van der Waals contact on commercial CdTe wafers for improved photovoltaic and solar panel production. Background: Cadmium Telluride (CdTe) is a common absorber used for thin-film optoelectronics and photovoltaics, including...
Published: 1/28/2026
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Inventor(s):
Yu Huang
,
Xiangfeng Duan
,
Bangyao Hu
Keywords(s):
Category(s):
Electrical
,
Electrical > Electronics & Semiconductors
,
Electrical > Electronics & Semiconductors > Waferscale Computing
,
Chemical
,
Chemical > Chemical Processing & Manufacturing
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Chemical > Instrumentation & Analysis
,
Electrical > Sensors
,
Energy & Environment
,
Energy & Environment > Energy Efficiency
,
Energy & Environment > Energy Generation
,
Materials
,
Materials > Semiconducting Materials
Θ-Phase Tantalum Nitride for Thermal Management and Electronics Applications (Case No. 2026-180)
Summary: Researchers in UCLA’s Department of Mechanical and Aerospace Engineering have developed a novel transition metal compound that demonstrates what is thought to be the highest thermal conductivity reported among metallic materials. The material is synthesized as a single, defect-free crystal, enabling unprecedented efficiency in heat transport....
Published: 1/20/2026
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Inventor(s):
Yongjie Hu
Keywords(s):
advanced thermal control materials
,
Composite Material
,
Electronics & Semiconductors
,
energy-efficient
,
heat control
,
heat controlling devices
,
heat dissipation
,
Heat Transfer
,
high conductivity
,
material science
,
Materials
,
Metals
,
nanocrystalline metals
,
Power Electronics
,
temperature control
,
thermal control
,
thermal control materials
,
thermal management
,
thermal management systems
,
thermal metamaterials
Category(s):
Chemical
,
Chemical > Chemical Processing & Manufacturing
,
Chemical > Synthesis
,
Electrical
,
Electrical > Electronics & Semiconductors > Thermoelectrics
,
Energy & Environment > Thermal
,
Materials
,
Materials > Metals
,
Mechanical > Heat Transfer
Smart Electric Vehicle (EV) Charging and Grid Integration Apparatus and Methods (Case No. 2010-903)
Summary Researchers at UCLA have developed a smart EV charging and grid integration system that uses real-time control, state estimation, and bidirectional energy flows to manage EV charging and vehicle-to-grid (V2G) operations. The system optimizes charging schedules based on grid constraints, user preferences, and energy market signals while ensuring...
Published: 10/28/2025
|
Inventor(s):
Rajit Gadh
,
Siddhartha Mal
,
Brahmavar Prabhu
,
Chi Cheng Chu
Keywords(s):
Category(s):
Energy & Environment
,
Energy & Environment > Energy Efficiency
,
Energy & Environment > Energy Storage
,
Energy & Environment > Energy Storage > Batteries
Ampule-Based Synthesis of Sulfur-Porous Carbon Composites for Lithium-Sulfur Batteries
Background Lithium/sulfur (Li/S) batteries are garnering significant attention as a promising solution for next-generation electrochemical energy storage. Their potential to revolutionize the battery industry stems from several key advantages that address the limitations of current lithium-ion (Li-ion) technology. These advantages include an exceptionally...
Published: 2/26/2026
|
Inventor(s):
Yoon Hwa
,
David Wright
,
Yuhui An
Keywords(s):
Chemicals
,
Energy storage
,
Engineering
,
Materials
,
Nanomaterials
,
Synthesis
Category(s):
Energy & Power
,
Physical Science
,
Advanced Materials/Nanotechnology
,
Semiconductors, Materials & Processes
Machine Learning-Enhanced Aircraft Landing Schedule Algorithm
Background The civil aviation industry is losing air traffic control talents during a time when the need for maintaining daily operations is surging. This situation leads to increased operational costs, higher safety concerns, an elevated workload for air traffic controllers, and frequent flight delays. It is reported that 20% of the civil flights...
Published: 2/26/2026
|
Inventor(s):
Yongming Liu
,
Yutian Pang
,
Jueming Hu
Keywords(s):
Category(s):
Physical Science
,
Artificial Intelligence/Machine Learning
,
Applied Technologies
Artificial nitrogenase enzymes for ambient-condition, decentralized ammonia production
Background Ammonia synthesis is foundational to global agriculture and chemical manufacturing, providing the primary source of fixed nitrogen for fertilizers, polymers, and pharmaceuticals. Traditional ammonia production through the Haber-Bosch process, however, operates under extreme conditions—temperatures exceeding 400°C and pressures...
Published: 1/13/2026
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Inventor(s):
Yi Lu
,
Hirbod Heidari
,
Markus Ribbe
,
Yilin Hu
,
Chi Chung Lee
,
Evan Mirts
Keywords(s):
Category(s):
Life sciences > Therapeutics > Synthetic biology
,
Life sciences > Metabolic engineering
Discovery of potent and selective D3 antagonist with alleviated hERG liability and optimized pharmacokinetic properties
One of the most challenging hurdles in creating safe and effective new medicines for many diseases is finding drugs that are effective without causing off-target cardiac issues, such as cardiac arrythmias. In collaboration with NIDA, scientists at NCATS have developed a series of novel and highly specific dopamine D3 receptor agonists and antagonists...
Published: 11/14/2025
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Inventor(s):
Khalida Shamim
,
Wenwei Huang
,
Wei Zheng
,
Catherine Chen
,
Xiuli Huang
,
Xin Hu
,
Xin Xu
,
Pranav Shah
,
Elias Padilha
,
Philip Sanderson
,
Amy Newman
Keywords(s):
Category(s):
Application > Therapeutics
,
Collaboration Sought > Licensing
,
Collaboration Sought > Materials Available
,
TherapeuticArea > Neurology
,
TherapeuticArea > Psychiatry/Mental Health
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025
|
Inventor(s):
Stephen Liggett
,
Donghwa Kim
,
Yu Chen
,
Jesper Madsen
,
Steven An
Keywords(s):
Pharmaceuticals
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
Automatic Detection and Quantification of Marine Macroalgae from Satellite Imagery
Advantages: Automates seaweed detection and quantification using satellite imagery Combines physics-based models and machine learning for accurate results Generates actionable seaweed maps at various spatial and temporal resolutions Applicable globally works on both Sargassum and Ulva blooms across different regions Summary: Massive seaweed...
Published: 6/10/2025
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Inventor(s):
Chuanmin Hu
,
Mengqiu Wang
Keywords(s):
Category(s):
Technology Classifications > Electronics > Electronics Laser
,
Technology Classifications > Data/AI > D/AI Imaging
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