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Search Results - xiangpeng+li
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SINGLE-CELL EPIGENOMIC PROFILING USING DROPLET FLUIDICS AND CHEMICALLY MODIFIED HYDROGELS
SINGLE-CELL EPIGENOMIC PROFILING USING DROPLET FLUIDICS AND CHEMICALLY MODIFIED HYDROGELS Researchers at UCSF have developed materials and methods for high throughput single cell epigenomic sequencing using a capture/profiling approach with hydrogel scaffolds, thus facilitating a scale and form of epigenomic profiling beyond what has been previously...
Published: 7/6/2023
|
Inventor(s):
Adam Abate
,
Xiangpeng Li
Keywords(s):
DNA Capture
,
Droplet
,
Epigenomic
,
High-Throughput
,
Hydrogel
,
Microfluidic
,
Single-Cell
Category(s):
Technology Classifications > Biology
PARTITIONING CELLS FOR HIGH-THROUGHPUT SINGLE-CELL SEQUENCING
PARTITIONING CELLS FOR HIGH-THROUGHPUT SINGLE-CELL SEQUENCING Researchers at UCSF have developed a method for high throughput single-cell multi-omic sequencing that is rapid, simple to operate, and offers key innovations over existing technologies. Single-cell sequencing technologies refer to the methods to obtain genomics, transcriptomics or multi-omics...
Published: 4/20/2023
|
Inventor(s):
Adam Abate
,
Xiangpeng Li
,
Benjamin Demaree
Keywords(s):
Genomic DNA
,
Hydrogel
,
Microfluidic
,
Partitioning
,
Sequencing
,
Single-Cell
,
Transcriptomics
Category(s):
Technology Classifications > Biology
Intelligent Multi-Beam Medium Access Control in Ku-Band for Mission-Oriented Mobile Mesh Networks
The Problem: There are existing similar technologies, but these technologies are not designed for mobile mission-oriented applications. The use of Ku-band frequency on two separate information transmission levels reduces interference common with current multi-beam antennas. Also, the Ku-band frequency is not the currently used frequency range...
Published: 2/27/2023
|
Inventor(s):
Fei Hu
,
xI Li
,
Sunil Kumar
Keywords(s):
Category(s):
Technology Classifications > Communication
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024
|
Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
POINT-OF-CARE AND IMPROVED DETECTION AND QUANTIFICATION OF BIOMOLECULES
POINT-OF-CARE AND IMPROVED DETECTION AND QUANTIFICATION OF BIOMOLECULES Researchers at UCSF and the Chan Zuckerberg Biohub have developed a workflow for accurate bulk quantitation of droplet digital PCR, which can be used in point-of-care clinical settings with minimal sample processing. The quantitation of nucleic acids is important for clinical...
Published: 10/26/2024
|
Inventor(s):
Adam Abate
,
Xiangpeng Li
Keywords(s):
Biomolecules
,
Diagnosis
,
Droplet Digital PCR
,
Fluorescence
,
High-Throughput
,
Microfluidics
,
SARS-CoV-2
Category(s):
Technology Classifications > Biology
SARS-CoV-2 Antibodies to Treat or Diagnose COVID-19
This invention includes multiple high affinity, human antibodies that selectively target the SARS-CoV-2 virus which is responsible for COVID-19. Each antibody was identified by screening an internally developed human single chain variable fragment (scFv) library against different components of the SARS-CoV-2 virus particle. Successful screening protocols...
Published: 5/6/2024
|
Inventor(s):
Xian Li
,
Xiaohua Lou
Keywords(s):
Category(s):
Clinical Area > Infectious Disease
,
Research Area > Infectious Diseases and Pathology
,
Technology Classifications > Research Tool > Antibodies
,
Technology Classifications > Therapeutic > Biologics
,
Technology Classifications > Therapeutic > Antibodies
IRF4-Targeted Therapies for Cancer, Transplant Rejection, and Autoimmune Disorders
This invention is a method of depleting or over-expressing the transcription factor, interferon regulatory factor 4 (IRF4), in T cells as therapeutic strategy for conditions which are highly regulated by the immune system. The inventors have established that IRF4 represses PD-1, Helios, and other molecules associated with T cell function, representing...
Published: 10/8/2024
|
Inventor(s):
Wenhao Chen
,
Xian Li
Keywords(s):
Category(s):
Technology Classifications > Therapeutic > Cell and Gene Therapies
,
Clinical Area > Transplantation
,
Clinical Area > Cancer
,
Clinical Area > Metabolic Disease, Inflammation, and Immunology
,
Research Area > Cancer
,
Research Area > Immunobiology and Inflammation
Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
|
Inventor(s):
Nasser Peyghambarian
,
Axel Schülzgen
,
Li Li
,
Jacques Albert
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Lasers & Other Sources
All-Fiber Multicore Fiber Laser Devices
Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...
Published: 4/3/2023
|
Inventor(s):
Nasser Peyghambarian
,
Axel Schülzgen
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Fiber Optics
,
Technology Classifications > Imaging & Optics > Lasers & Other Sources
Bioactive Coating
Available for: Licensing <h2>Summary</h2>{{start}}A novel method of creating an inter-locked (high bond strength) bioactive coating on metallic substrates for orthopaedic applications.{{end}}<h2>The Technology and its Advantages</h2>The lack of methodology for producing strongly-bonded bioactive coatings on metallic alloys is...
Published: 9/23/2024
|
Inventor(s):
Mohan Edirisinghe
,
Jie Huang
,
Xiang Li
,
William Bonfield
,
Minoo Esat
Keywords(s):
Chemicals & Materials
Category(s):
Medical Devices