Search Results - vascular

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Mouse Model of Hutchinson-Gilford Progeria Syndrome (HGPS) and Vascular Abnormalities (G608G) mutated form of human LNMA) for Therapeutic Development
Children with Hutchinson-Gilford progeria syndrome (HGPS) suffer from acceleration of certain aging symptoms, mainly cardiovascular disease that generally leads to death from myocardial infarction and/or stroke. The cause of HGPS has been discovered to be a de novo point mutation in lamin A (LNMA) gene. NHGRI Scientist have generated a transgenic...
Published: 10/28/2024   |   Inventor(s): Francis Collins, Maria Eriksson, Renee Varga, Michael Erdos
Keywords(s): Abnormalities, HGPS, Hutchinson-Gilford, Listed LPM Maddox as of 4/15/2015, Model, Mouse, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Progeria, RXXXXX, Syndrome, vascular, VEXXXX, VPXXXX, XEXXXX
Category(s): Application > Research Materials, TherapeuticArea > Infectious Disease, Application > Therapeutics, TherapeuticArea > Endocrinology, TherapeuticArea > Ophthalmology, TherapeuticArea > Dental, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Neurology
Device for Vascular Dilation
The invention is an enhanced vascular dilator that eliminates the vascular injury caused by the size mismatch between vascular introducer sheaths and vascular dilators, as the two are advanced into a blood vessel. The invention provides a “shoulder” to match the diameter of the introducer sheath so that there is a smooth transition, without size mismatch,...
Published: 10/28/2024   |   Inventor(s): Ozgur Kocaturk, Adam Greenbaum, Robert Lederman
Keywords(s): AA2XXX, AA4CXX, AAXXXX, AXXXXX, Dilator, Segmented, vascular, YFXXXX
Category(s): Collaboration Sought > Collaboration
Method for the Diagnosis and Treatment of Vascular Disease
Cardiovascular disease is a major health risk throughout the industrialized world. Atherosclerosis, the most prevalent of cardiovascular diseases, is the principal cause of heart attack, stroke, and gangrene of the extremities. It is also the principal cause of death in the United States. This invention portrays a method for diagnosing decreased vascular...
Published: 10/28/2024   |   Inventor(s): Arshed Quyyumi, Jonathan Hill, Toren Finkel
Keywords(s): Cells, Diagnosis, Disease, Endothelial, IAXXXX, IXXXXX, Listed LPM Nguyen-Antczak as of 4/15/2015, Method, Patent Category - Biotechnology, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Progenitor, treatment, vascular
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics
Electrochemical Pressure Sensor
Pressure/force sensors and transducers have wide utility in mechanical, medical and industrial applications, with each industry striving for increased performance. Three key features determine how successful a pressure sensor may be: sensitivity, durability, and cost. Because of their robust and inexpensive nature, transformative electrochemical pressure/force...
Published: 2/23/2023   |   Inventor(s): Jeffrey LaBelle, Austin Feldman, Mary Siuba, Ross Carlton, Jeffrey Andrade
Keywords(s): Automotive, Bio-Technology, Brain and Machine Interface, Detection, Device, Flexible electronics, Sensors, Transplantation, Vascular
Category(s): Chemical/Biological Sensors, Life Science (All LS Techs), Medical Devices