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Novel three-dimensional, conformal microelectrode arrays for interrogating and manipulating three-dimensional cell culture systems

A flexible, biocompatible microelectrode array wraps around 3D cell cultures such as organoids, enabling comprehensive electrical recording and stimulation for advanced research, drug testing, and personalized medicine, overcoming the limitations of traditional flat electrode arrays. Background: Three-dimensional (3D) cell culture systems, such as...

Published: 1/29/2026 | Inventor(s): Susan Sharfstein, Nathaniel Cady, Yubing Xie, Natalya Tokranova, Anthony Manning, Fernando Pesantez Torres

Keywords(s): 3D culture, 3D flexible microelectrode, electrophysiology, microelectrode array, microfabrication, neurodegeneration, organoid, polymer materials, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering

Pharmacological strategy to treat hydrocephalus

This technology offers a non-surgical treatment for hydrocephalus by using drugs to enhance the removal of harmful macromolecules from the brain’s ventricles, targeting specific cellular transport mechanisms to reduce fluid buildup and disease progression. Background: Hydrocephalus is a neurological disorder characterized by the abnormal accumulation...

Published: 1/29/2026 | Inventor(s): Satish Krishnamurthy, David Lehmann

Keywords(s): hydrocephalus, pharmacology, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare

Polyphasic Ultrasonic Power transfer for wireless charging of implants.

This technology uses multiple piezoelectric transducers with controlled phase shifts to create engineered ultrasonic waves, enabling efficient, wireless power transfer through tissue to implanted medical devices or sensors, overcoming limitations of traditional electromagnetic intra-body power transfer systems. Background: Wireless power transfer...

Published: 1/29/2026 | Inventor(s): Amit Sangwan, Dante Riccoboni

Keywords(s): bioelectronics, biomedical engineering, biotechnology, Medical Device, Technologies

Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare

“Smart” Electronic Rotating Hemostatic Valve and Tuohy-Borst Adapter with Integrated Activation and Force Sensors with Interface with Heads-Up Electronic Displays and Cloud-Based Data Analysis To Optimize Technical Safety, Display Live Quantified Operator Variables and Inform Individualized Procedural Technique

This technology measures, records, and displays force measurements exerted on catheters, providing valuable data to improve patient outcomes. Background: Rotating hemostatic valves (RHV) and Tuohy-Borst adapters (TBA) are used with catheter-based and other relevant procedures. Currently available RHVs and TBAs lack integrated sensors to provide feedback...

Published: 1/29/2026 | Inventor(s): Hesham Masoud, Andrew Decker

Keywords(s): Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare

Self-delivery USP10 siRNA to promote regenerative healing-new IP

This technology employs an engineered self-delivering siRNA to selectively reduce USP10 protein levels in tissues, thereby promoting regenerative healing and suppressing pathological scarring. Preclinical studies in the eye demonstrate a favorable safety profile and robust efficacy, supporting the potential of this approach for treating fibrotic disease...

Published: 1/29/2026 | Inventor(s): Audrey Bernstein, Sean McCauley, Alexey Wolfson, Tere Williams

Keywords(s): fibrosis, opthalmology, scarring, siRNA, skin diseases, Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Campus > Upstate Medical University

Rapid, robust, and near point-of-care saliva-based nucleic acid detection of dengue virus infections

This technology enables rapid, non-invasive detection and differentiation of all four dengue virus serotypes using saliva samples, with advanced qPCR and RT-LAMP assays, making dengue diagnosis easier, faster, and more accessible without the need for blood draws. Background: Dengue virus (DENV) is a major global health concern, with hundreds of millions...

Published: 1/29/2026 | Inventor(s): Frank Middleton, Stephen Thomas, Adam Waickman, Timothy Rooney

Keywords(s): diagnostics, disease diagnosis, isothermal amplification (LAMP), nucleic acid, PCR, RNA viruses, saliva, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Screens and Assays, Technology Classifications > Biomedical Science and Engineering

Sulfonium Lipid Nanoparticles for Intranasal mRNA Delivery to Lung Epithelial and Immune Cells

This technology uses specially designed sulfonium lipid nanoparticles to deliver mRNA directly to lung cells through the nose, offering a non-invasive, more effective and targeted treatment for pulmonary diseases like asthma and cystic fibrosis. Background: The field of pulmonary medicine faces significant challenges in the treatment of diseases...

Published: 1/29/2026 | Inventor(s): Yamin Li, Yuqin Men

Keywords(s): active pharmaceutical ingredient, chemicals, drug delivery, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery

Therapeutic backbone and scaffold modification in the physiological environment

This technology enables precise, water-based chemical modification of proteins at their C-terminus using a single, easily removable reagent, preserving protein structure and function and allowing attachment of diverse functional groups for therapeutic, research, and diagnostic applications. Background: Proteins and polypeptides play a central role...

Published: 1/29/2026 | Inventor(s): Qiang Zhang

Keywords(s): antibody therapy, GLP-1 secretion, Insulin, protein engineering, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering

Enhanced Fluorophore Discrimination in Fluorescence Microscopy Using Multi View Spectral Unmixing with Photobleaching Dynamics

This technology allows researchers to more easily distinguish hundreds of fluorescent labels in a single image, useful for a wide variety of biological applications. Background: There are hundreds to thousands of different cells or other structures that can be labeled with fluorescent reporters in a biological sample, and then imaged on a fluorescence...

Published: 1/29/2026 | Inventor(s): Alex Valm, Yunlong Feng, Ruogu Wang

Keywords(s): Technologies

RNA-aptamer-mediated Bacteriophage Purification

A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...

Published: 1/29/2026 | Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen

Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines

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