Search Results - swen+besselink

13 Results

Sort By:

Researchers at UC Berkeley have developed novel strategies for the delivery of CRISPR gene editing components. While CRISPR-based gene editing holds great promise for treating genetic diseases, it often involves DNA breaks or base changes that can cause off-target effects, cell damage, or unpredictable outcomes. Additionally, these changes are often...

Published: 10/23/2025 | Inventor(s): James Nunez, Da Xu, Swen Besselink

Keywords(s): CRISPR, Epigenetics

Category(s): Technology Classifications > Biology

Bioplatform to Identify and Characterize Pathogens and Therapies against Tuberculosis and Other Granulomatous Diseases.

Treatment for human tuberculosis (TB) and other granulomatous diseases would benefit from high- throughput screening (HTS)-compatible platform replicating physiological conditions in hallmark granuloma lesions. However, currently available screening platforms and 2-D and 3-D cell culture systems lack throughput and key features, and relevant microenvironments...

Published: 5/9/2025 | Inventor(s): Suraj Sable, James Posey, Wen Li, Allison Kline

Keywords(s):

Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Heavy Metal Sensing

VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...

Published: 10/21/2025 | Inventor(s): Wen Li, Hasan Banna, James Siegenthaler, Mohammad Kafi Kangi, Tumi Olason

Keywords(s):

Category(s): Agriculture, Analytical Instruments, Environment, Test and Measurement

Self-neutralizing air-breathing thruster and method of neutralization

An ion-engine is the cutting edge for atmospheric air-breathing engines. The technology depends on ionizing and neutralizing atmospheric air particles which create thrust. This unique possibility makes it an ideal choice for very-low-orbit satellites. Very- low-orbit satellite capabilities have benefits such as higher resolution for images, weight...

Published: 9/12/2025 | Inventor(s): Michael Keidar, Anmol Taploo, Li Lin

Keywords(s):

Category(s): Technology Classifications > Computers Electronics & Software, Technology Classifications > Computers Electronics & Software > Aviation, Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment, Technology Classifications > Industrial or Consumer Tech > Industrial Manufacturing

Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors

Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...

Published: 9/12/2025 | Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 9/12/2025 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Cold atmospheric plasma-stimulated media for treating cancers

For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...

Published: 9/12/2025 | Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics

Implantable Neural Microelectrodes and Fabrication Method

Executive SummaryMicroelectrodes have become vital in the current-day attempt to map and understand the human brain, as well as delivering unique therapeutic solutions. These microelectrodes are able to work as biosensors, picking up changes in potential and electrophysiology. In particular, extracellular sensors can record data on neurotransmitter...

Published: 2/17/2023 | Inventor(s): Wen Li, Yue Guo, Thomas Schuelke, Michael Becker, Robert Rechenberg, Cory Rusinek

Keywords(s):

Category(s): Advanced Materials, Biotechnology, Devices

Flexible Hybrid Diamond Biosensor

Executive SummaryA unique fabrication method creates a new flexible and implantable thin film sensor for the biochemical, medical and neural engineering fields. This diamond-polymer hybrid demonstrates improved biocompatibility, durability and chemical sensing capabilities. Description of TechnologyThe rigidness and attachment incompatibilities of...

Published: 6/8/2021 | Inventor(s): Wen Li, Bin Fan, Michael Becker, Robert Rechenberg

Keywords(s):

Category(s): Advanced Materials, Devices

Wireless Intraocular Pressure Sensor to Monitor Glaucoma Patients

Executive SummaryGlaucoma is a leading cause of blindness that affects up to 3 million people in American. It can remain undetected until permanent vision loss is present. Measuring eye pressure during an office visit is a standard diagnostic tool. However, this measurement can only report on pressure during a brief time sample. Patients with variable...

Published: 6/15/2023 | Inventor(s): Wen Li, Arthur Weber, Mohammad Hossein Kouhani

Keywords(s):

Category(s): Medical, Biotechnology, Test and Measurement

1 2