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Search Results - sanjaya+sanjaya
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Tumor-pH–Triggered Doxorubicin Prodrug with On-Demand Shelf-Stable Precursor
This invention introduces a small-molecule doxorubicin prodrug that remains inert in blood and rapidly activates in the mildly acidic tumor microenvironment. Featuring a shelf-stable maleimide pre-prodrug that converts on demand to the ultra-acid-labile DMA form, it enables targeted chemotherapy with improved selectivity, scalable synthesis, and reduced...
Published: 10/10/2025
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Inventor(s):
Ming An
,
Lan Yao
,
Vladyslav Nazarenko
Keywords(s):
Technologies
Category(s):
Campus > Binghamton University
Non-invasive quantitative monitor of depth of anesthesia and sedation
PAGE TITLE Overview PAGE SUMMARY Drexel researchers have developed a non-invasive device for quantitative, real-time monitoring of the depth of anesthesia both during general anesthesia in surgery and sedation in endoscopy and colonoscopy procedures. The device uses functional near-infrared (fNIR) spectroscopy to measure physiological parameters...
Published: 9/4/2025
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Inventor(s):
Kambiz Pourrezaei
,
Kurtulus Izzetoglu
,
Banu Onaral
,
Jay Horrow
,
Scott Bunce
,
Meltem Izzetoglu
Keywords(s):
NIR - near infrared
Category(s):
Medical Devices, Diagnostics & Biosensors
Ampule-Based Synthesis of Sulfur-Porous Carbon Composites for Lithium-Sulfur Batteries
Background Lithium/sulfur (Li/S) batteries are garnering significant attention as a promising solution for next-generation electrochemical energy storage. Their potential to revolutionize the battery industry stems from several key advantages that address the limitations of current lithium-ion (Li-ion) technology. These advantages include an exceptionally...
Published: 10/30/2025
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Inventor(s):
Yoon Hwa
,
David Wright
,
Yuhui An
Keywords(s):
Chemicals
,
Energy storage
,
Engineering
,
Materials
,
Nanomaterials
,
Synthesis
Category(s):
Energy & Power
,
Physical Science
,
Advanced Materials/Nanotechnology
,
Semiconductors, Materials & Processes
Compositions and Methods for Producing Dendritic Cell-based Vaccines with Enhanced Efficacy
Summary: The National Cancer Institute (NCI) is seeking research co-development partners and/or licensees for NCI’s compositions and methods to enhance the efficacy of dendritic cell (DC)-based cancer vaccines. Description of Technology: Current dendritic cell (DC)-based cancer vaccines are limited by impaired DC function due to cancer-driven...
Published: 8/21/2025
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Inventor(s):
Jay Berzofsky
,
Shweta Tiwary
Keywords(s):
Category(s):
TherapeuticArea > Oncology
,
TherapeuticArea > Immunology
,
Application > Therapeutics
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
Water Immersion Multi-Slit Portable In Vivo Confocal Ophthalmoscope
This technology is a low-cost, portable, scan-less in vivo confocal ophthalmoscope (PICO) that uses a water-immersion objective lens in combination with a multi-slit illumination and detection system. It enables high-resolution, non-invasive imaging of the anterior segment and external structures of the eye at the cellular and subcellular level. The...
Published: 7/22/2025
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Inventor(s):
Dongkyun Kang
,
Kenneth Marcelino
,
Momoka Sugimura
,
Jaya Chidambaram
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Displays
,
Technology Classifications > Imaging & Optics > Lens & System Design
,
Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
,
Technology Classifications > Imaging & Optics > Sensors and Detection
,
Technology Classifications > Imaging & Optics > Ophthalmology
,
Technology Classifications > Healthcare Portfolios > Ophthalmology
,
Technology Classifications > Medical Devices > Diagnostic
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025
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Inventor(s):
Stephen Liggett
,
Donghwa Kim
,
Yu Chen
,
Jesper Madsen
,
Steven An
Keywords(s):
Pharmaceuticals
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
Ophthalmoscopic Device and Method for Capturing Images using the Same
The invention is a low-cost, portable in-vivo confocal ophthalmoscope (PICO) designed to capture microscopic images of the anterior segment of the eye and external eye structures without direct contact. The device is compact, lightweight, and capable of providing high-resolution imaging for real-time diagnostics. This ophthalmoscope can attach to standard...
Published: 7/22/2025
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Inventor(s):
Dongkyun Kang
,
Kenneth Marcelino
,
Momoka Sugimura
,
Jaya Chidambaram
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Lens & System Design
,
Technology Classifications > Medical Devices > Diagnostic
,
Technology Classifications > Imaging & Optics > Ophthalmology
,
Technology Classifications > Healthcare Portfolios > Ophthalmology
Acquisition – Software to Control Acquisition of Images for Near-Earth Object Survey Operations
The Acquisition subsystem in the Catalina Sky Survey (CSS) software suite manages the operation of telescopes and instruments to capture data on asteroids and Near-Earth Objects (NEOs). Once areas of the sky are selected for observation, Acquisition takes over, accepting the input from the Planner subsystem and coordinating the telescope, camera, and...
Published: 12/9/2024
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Inventor(s):
A Departmental Work
Keywords(s):
Category(s):
Technology Classifications > Software & Information Technology > Open Source
,
Technology Classifications > Software & Information Technology
Planner – Planning Software for Near-Earth Object Survey Operations
The Planner subsystem in the Catalina Sky Survey (CSS) software suite is designed to help observers efficiently plan nightly asteroid and Near-Earth Object (NEO) observations. By displaying a virtual map of the sky, it helps ensure that areas previously searched, or areas unlikely to be productive, are avoided. The map shows the telescope’s current...
Published: 12/9/2024
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Inventor(s):
A Departmental Work
Keywords(s):
Category(s):
Technology Classifications > Software & Information Technology > Open Source
,
Technology Classifications > Software & Information Technology
Processing – Software to Process and Analyze Images for NEO Survey
The Processing subsystem in the Catalina Sky Survey (CSS) software suite is a streamlined pipeline designed to handle raw images captured by telescopes during asteroid and Near-Earth Object (NEO) surveys. This pipeline processes the images through multiple stages, such as calibrating for optical distortions, extracting star or asteroid positions, and...
Published: 12/9/2024
|
Inventor(s):
A Departmental Work
Keywords(s):
Category(s):
Technology Classifications > Software & Information Technology > Open Source
,
Technology Classifications > Software & Information Technology
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