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Search Results - sanjaya+sanjaya
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Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 3/23/2026
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Updated: 3/23/2026
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Inventor(s):
Alex McGhee
,
Kelvin Pond
,
A Departmental Work
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Sensors and Detection
,
Technology Classifications > Engineering & Physical Sciences > Photonics
,
Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
,
Technology Classifications > Life Sciences > Diagnostics
,
Technology Classifications > Research Tools > Screening assays
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026
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Updated: 2/9/2026
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Inventor(s):
A Departmental Work
,
Michael Brown
Keywords(s):
Category(s):
Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
,
Technology Classifications > Research Tools
Analysis of Immune Repertoire with Fluorogenic Probes
Rapid analysis of T cells for the diagnosis of diseases in which the T cell repertoire is altered. Cells are distributed in aqueous droplets and their T cell receptor mRNAs are amplified in presence of “sloppy” molecular beacons. The melt profiles of molecular beacons in thousands of droplets reveals the T cell repertoire of...
Published: 3/16/2026
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Updated: 2/9/2026
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Inventor(s):
Sanjay Tyagi
,
Fred Kramer
,
Salvatore Marras
,
Ryan Dikdan
,
Stan Kwang
Keywords(s):
Category(s):
Technology Classifications > Diagnostics
Thin-film freeze-dried antibiotic powders for fixed-dose pulmonary delivery
Background Pulmonary diseases such as nontuberculous mycobacterial infections and chronic obstructive pulmonary disease (COPD) remain major global health challenges, often requiring long-term antibiotic therapy delivered directly to the lungs to achieve effective pathogen clearance. Inhaled drug delivery provides a promising approach to increase local...
Published: 1/30/2026
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Updated: 1/30/2026
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Inventor(s):
Zhengrong Cui
,
Reem Zaki
,
Michael Sandoval
,
Robert Williams
,
Jay Peters
Keywords(s):
Category(s):
Life sciences > Therapeutics > Formulation
,
Life sciences > Therapeutics > Drug delivery
Non-invasive quantitative monitor of depth of anesthesia and sedation
PAGE TITLE Overview PAGE SUMMARY Drexel researchers have developed a non-invasive device for quantitative, real-time monitoring of the depth of anesthesia both during general anesthesia in surgery and sedation in endoscopy and colonoscopy procedures. The device uses functional near-infrared (fNIR) spectroscopy to measure physiological parameters...
Published: 2/12/2026
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Updated: 9/4/2025
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Inventor(s):
Kambiz Pourrezaei
,
Kurtulus Izzetoglu
,
Banu Onaral
,
Jay Horrow
,
Scott Bunce
,
Meltem Izzetoglu
Keywords(s):
NIR - near infrared
Category(s):
Medical Devices, Diagnostics & Biosensors
Ampule-Based Synthesis of Sulfur-Porous Carbon Composites for Lithium-Sulfur Batteries
Background Lithium/sulfur (Li/S) batteries are garnering significant attention as a promising solution for next-generation electrochemical energy storage. Their potential to revolutionize the battery industry stems from several key advantages that address the limitations of current lithium-ion (Li-ion) technology. These advantages include an exceptionally...
Published: 2/26/2026
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Updated: 8/21/2025
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Inventor(s):
Yoon Hwa
,
David Wright
,
Yuhui An
Keywords(s):
Chemicals
,
Energy storage
,
Engineering
,
Materials
,
Nanomaterials
,
Synthesis
Category(s):
Energy & Power
,
Physical Science
,
Advanced Materials/Nanotechnology
,
Semiconductors, Materials & Processes
Compositions and Methods for Producing Dendritic Cell-based Vaccines with Enhanced Efficacy
Summary: The National Cancer Institute (NCI) is seeking research co-development partners and/or licensees for NCI’s compositions and methods to enhance the efficacy of dendritic cell (DC)-based cancer vaccines. Description of Technology: Current dendritic cell (DC)-based cancer vaccines are limited by impaired DC function due to cancer-driven...
Published: 8/21/2025
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Updated: 7/15/2025
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Inventor(s):
Jay Berzofsky
,
Shweta Tiwary
Keywords(s):
Category(s):
TherapeuticArea > Oncology
,
TherapeuticArea > Immunology
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Application > Therapeutics
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
Water Immersion Multi-Slit Portable In Vivo Confocal Ophthalmoscope
This technology is a low-cost, portable, scan-less in vivo confocal ophthalmoscope (PICO) that uses a water-immersion objective lens in combination with a multi-slit illumination and detection system. It enables high-resolution, non-invasive imaging of the anterior segment and external structures of the eye at the cellular and subcellular level. The...
Published: 7/22/2025
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Updated: 6/18/2025
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Inventor(s):
Dongkyun Kang
,
Kenneth Marcelino
,
Momoka Sugimura
,
Jaya Chidambaram
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Displays
,
Technology Classifications > Imaging & Optics > Lens & System Design
,
Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
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Technology Classifications > Imaging & Optics > Sensors and Detection
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Technology Classifications > Imaging & Optics > Ophthalmology
,
Technology Classifications > Healthcare Portfolios > Ophthalmology
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Technology Classifications > Medical Devices > Diagnostic
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025
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Updated: 5/27/2025
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Inventor(s):
Stephen Liggett
,
Donghwa Kim
,
Yu Chen
,
Jesper Madsen
,
Steven An
Keywords(s):
Pharmaceuticals
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
Ophthalmoscopic Device and Method for Capturing Images using the Same
The invention is a low-cost, portable in-vivo confocal ophthalmoscope (PICO) designed to capture microscopic images of the anterior segment of the eye and external eye structures without direct contact. The device is compact, lightweight, and capable of providing high-resolution imaging for real-time diagnostics. This ophthalmoscope can attach to standard...
Published: 7/22/2025
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Updated: 4/14/2025
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Inventor(s):
Dongkyun Kang
,
Kenneth Marcelino
,
Momoka Sugimura
,
Jaya Chidambaram
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Lens & System Design
,
Technology Classifications > Medical Devices > Diagnostic
,
Technology Classifications > Imaging & Optics > Ophthalmology
,
Technology Classifications > Healthcare Portfolios > Ophthalmology
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