Search Results - sanjaya+sanjaya

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S100A4 Monoclonal Antibody for Therapeutic and Diagnostic Use
Cancer metastasis are responsible for ~90% of cancer associated deaths. Recent studies suggest that immune cells play critical roles in promoting metastasis, especially myeloid cells from the bone marrow. UTHealth researchers, with researchers from The Methodist Hospital, observed a highly conserved expression of S100A4 in immune suppressive myeloid...
Published: 10/21/2024   |   Inventor(s): Zhiqiang An, Ningyan Zhang
Keywords(s):  
Category(s): Neurology/Neurosurgery, Oncology, Therapeutics
LILRB2 Monoclonal Antibody for Therapeutic and Diagnostic Uses of Neurodegenerative Diseases
Triggering Receptor Expressed on Myeloid cells 2 (TREM2) plays a key regulatory role in Alzheimer’s disease (AD) by controlling microglia activation and metabolic activities in brain tissues. TREM2 signaling inhibition is mediated by leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2). UTHealth inventors created and engineered...
Published: 10/21/2024   |   Inventor(s): Zhiqiang An, Ningyan Zhang
Keywords(s):  
Category(s): Neurology/Neurosurgery, Therapeutics
Novel cermet composite for nuclear waste immobilization
​ 1.5-inch diameter cermet synthesized using hot uniaxial sintering Invention Summary: Nuclear power generates ~10% of electricity globally and ~20% in developed economies. High-level waste, expected to be produced at the back end of advanced reactor fuel cycles, includes metals, oxides, halide salts, and carbon/graphite...
Published: 10/9/2024   |   Inventor(s): Ashutosh Goel, John Vienna, John McCloy, S Sundaram, Aditya Kumar, Hans-Conrad zur Loye, Jake Amoroso
Keywords(s):  
Category(s): Technology Classifications > Energy & Battery, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
Food Demonstration Guide
The Food Demonstration Guide is a comprehensive resource developed to enhance the quality and safety of food demonstrations conducted under the Arizona Department of Health Services' Supplemental Nutrition Assistance Program Education (SNAP-Ed) and Women, Infants, and Children (WIC) programs. This guide aims to train SNAP-Ed and WIC staff on best...
Published: 10/9/2024   |   Inventor(s): Jennifer Parlin, A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Creative Works, Technology Classifications > Agriculture & Horticulture > Food Science & Nutrition
SuperSelective PCR Primers
​ Structure of a SuperSelective primer for the detection and quantitation of rare mutant sequences in the presence of 1,000,000 wild-type sequences; and a demonstration that the number of amplification cycles required to generate a signal above background is inversely linearly proportional to the logarithm of the number of mutant molecules in the original...
Published: 10/9/2024   |   Inventor(s): Salvatore Marras, Diana Vargas-Gold, Sanjay Tyagi, Fred Kramer
Keywords(s): Anti-cancer, Sensors & Probes
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Diagnostics
Oxynitidine Derivatives Useful as Inhibitors of Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) for Treating Cancer
Summary: The National Cancer Institute (NCI) is actively seeking potential licensees and/or co-development research collaboration partners interested in advancing oxynitidine derivatives as novel inhibitors of topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 (TDP1) for cancer treatment. These TOPI and TDP1 inhibitors, when administered...
Published: 9/18/2024   |   Inventor(s): Yves Pommier, Lin-kun An, Keli Agama, Evgeny Kiselev, Azhar Ravji
Keywords(s): Benzophenanthridine Derivatives, Benzophenanthridinone, Camptothecin, Dihydrobenzophenanthridine, IRINOTECAN, Oxynitidine, Pommier, Tdp1, TOP1, Topoisomerase 1B, Topotecan, Tyrosyl-DNA Phosphodiesterase 1
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Therapeutics
Combination therapy for the treatment of triple negative breast cancer
Summary Researchers at OHSU have discovered a novel combination therapy for triple negative breast cancer, which increases immune responses, causes tumor regression and improves survival in animal models. Technology Overview Triple negative breast cancer (TNBC) represents one of the most aggressive forms of all breast cancer subtypes with a very...
Published: 9/17/2024   |   Inventor(s): Sanjay Malhotra, Lisa Coussens, Dhanir Tailor, Sushil Kumar, Arpit Dheeraj
Keywords(s): Therapeutics, Therapeutics - Cancer
Category(s): Therapeutics
System and Methods for Fluidic Control in Ophthalmic Procedures (Case No. 2024-229)
Summary: Researchers in the Mechanical Engineering Department at UCLA developed an innovative mechatronic system that can perform fast and accurate pressure regulation during cataract surgeries. Background: Despite being generally safe and successful, cataract surgery has a complication rate of about 6%, which is concerning given the high volume...
Published: 10/31/2024   |   Inventor(s): Tsu-Chin Tsao, Yu-Ting (Kevin) Lai, Aya Barzelay
Keywords(s): biomedical sensors, Intraocular Lens , Ophthalmology, Robotic Surgery
Category(s): Mechanical > Instrumentation, Medical Devices > Hospital Systems, Medical Devices > Surgical Tools, Medical Devices > Monitoring And Recording Systems, Therapeutics > Ophthalmology
In the Americas Season 10
In the Americas with David Yetman is an HDTV series that takes an in depth look at the heartland of Arizona, New Mexico, Sonora, and Chihuahua, and its peripheries and brings the region into the spotlight for the general audience. This show undertakes a new approach to travel and adventure with a focus on the western continents and islands. Season 10...
Published: 7/29/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Creative Works
An amino acid hybrid of aCGRP to treat cardiovascular disease
Reference #: 01645 The University of South Carolina is offering licensing opportunities for An Amino Acid Hybrid of a CGRP to Treat Cardiovascular Disease. Background: Heart failure is a chronic condition affecting millions of people worldwide, often leading to reduced lifespan and poor quality of life. The American Heart Association (AHA) estimates...
Published: 8/29/2024   |   Inventor(s): Jay Potts, Ambrish Kumar, Donald Dipette
Keywords(s):  
Category(s): Biomedical and Life Sciences, Health Sciences
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