Search Results - sanjaya+sanjaya

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High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025   |   Inventor(s): Stephen Liggett, Donghwa Kim, Yu Chen, Jesper Madsen, Steven An
Keywords(s): Pharmaceuticals, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals
Ophthalmoscopic Device and Method for Capturing Images using the Same
The invention is a low-cost, portable in-vivo confocal ophthalmoscope (PICO) designed to capture microscopic images of the anterior segment of the eye and external eye structures without direct contact. The device is compact, lightweight, and capable of providing high-resolution imaging for real-time diagnostics. This ophthalmoscope can attach to standard...
Published: 4/14/2025   |   Inventor(s): Dongkyun Kang, Kenneth Marcelino, Momoka Sugimura, Jaya Chidambaram
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Imaging & Optics > Ophthalmology, Technology Classifications > Healthcare Portfolios > Ophthalmology
Acquisition – Software to Control Acquisition of Images for Near-Earth Object Survey Operations
The Acquisition subsystem in the Catalina Sky Survey (CSS) software suite manages the operation of telescopes and instruments to capture data on asteroids and Near-Earth Objects (NEOs). Once areas of the sky are selected for observation, Acquisition takes over, accepting the input from the Planner subsystem and coordinating the telescope, camera, and...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Planner – Planning Software for Near-Earth Object Survey Operations
The Planner subsystem in the Catalina Sky Survey (CSS) software suite is designed to help observers efficiently plan nightly asteroid and Near-Earth Object (NEO) observations. By displaying a virtual map of the sky, it helps ensure that areas previously searched, or areas unlikely to be productive, are avoided. The map shows the telescope’s current...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Processing – Software to Process and Analyze Images for NEO Survey
The Processing subsystem in the Catalina Sky Survey (CSS) software suite is a streamlined pipeline designed to handle raw images captured by telescopes during asteroid and Near-Earth Object (NEO) surveys. This pipeline processes the images through multiple stages, such as calibrating for optical distortions, extracting star or asteroid positions, and...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Monitor – Software to Monitor Status of New and Recently Discovered Objects for NEO Survey
The Monitor subsystem in the Catalina Sky Survey (CSS) software suite is designed to help track the status of newly discovered and recently observed asteroids and Near-Earth Objects (NEOs). It gathers data from various public sources, such as the Minor Planet Center and other NEO survey programs, to provide a clear and prioritized summary of which objects...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Control - An Executive Program for Near-Earth Object Survey Operations
The Catalina Sky Survey (CSS) software suite is designed to detect and track Near-Earth Objects (NEOs), such as asteroids, that may pose a collision risk with Earth. By coordinating observations and data processing through multiple subsystems, the suite enables accurate tracking of these objects. The software manages telescope operations, image acquisition,...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology, Technology Classifications > Software & Information Technology > Open Source
S100A4 Monoclonal Antibody for Therapeutic and Diagnostic Use
Cancer metastasis are responsible for ~90% of cancer associated deaths. Recent studies suggest that immune cells play critical roles in promoting metastasis, especially myeloid cells from the bone marrow. UTHealth researchers, with researchers from Houston Methodist Hospital, observed a highly conserved expression of S100A4 in immune suppressive myeloid...
Published: 5/9/2025   |   Inventor(s): Zhiqiang An, Ningyan Zhang
Keywords(s):  
Category(s): Neurology/Neurosurgery, Oncology, Therapeutics
LILRB2 Monoclonal Antibody for Therapeutic and Diagnostic Uses of Neurodegenerative Diseases
Triggering Receptor Expressed on Myeloid cells 2 (TREM2) plays a key regulatory role in Alzheimer’s disease (AD) by controlling microglia activation and metabolic activities in brain tissues. TREM2 signaling inhibition is mediated by leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2). UTHealth inventors created and engineered...
Published: 10/21/2024   |   Inventor(s): Zhiqiang An, Ningyan Zhang
Keywords(s):  
Category(s): Neurology/Neurosurgery, Therapeutics
Novel cermet composite for nuclear waste immobilization
​ 1.5-inch diameter cermet synthesized using hot uniaxial sintering Invention Summary: Nuclear power generates ~10% of electricity globally and ~20% in developed economies. High-level waste, expected to be produced at the back end of advanced reactor fuel cycles, includes metals, oxides, halide salts, and carbon/graphite...
Published: 5/22/2025   |   Inventor(s): Ashutosh Goel, John Vienna, John McCloy, S Sundaram, Aditya Kumar, Hans-Conrad zur Loye, Jake Amoroso
Keywords(s):  
Category(s): Technology Classifications > Energy & Battery, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
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