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Search Results - fred+kramer
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Analysis of Immune Repertoire with Fluorogenic Probes
Rapid analysis of T cells for the diagnosis of diseases in which the T cell repertoire is altered. Cells are distributed in aqueous droplets and their T cell receptor mRNAs are amplified in presence of “sloppy” molecular beacons. The melt profiles of molecular beacons in thousands of droplets reveals the T cell repertoire of...
Published: 3/16/2026
|
Inventor(s):
Sanjay Tyagi
,
Fred Kramer
,
Salvatore Marras
,
Ryan Dikdan
,
Stan Kwang
Keywords(s):
Category(s):
Technology Classifications > Diagnostics
SuperSelective PCR Primers
Structure of a SuperSelective primer for the detection and quantitation of rare mutant sequences in the presence of 1,000,000 wild-type sequences; and a demonstration that the number of amplification cycles required to generate a signal above background is inversely linearly proportional to the logarithm of the number of mutant molecules in the original...
Published: 2/20/2026
|
Inventor(s):
Salvatore Marras
,
Diana Vargas-Gold
,
Sanjay Tyagi
,
Fred Kramer
Keywords(s):
Anti-cancer
,
Sensors & Probes
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Research Tools
,
Technology Classifications > Diagnostics